Výsledky vyhledávání - "Kwang-Hyun Choi"

Comparison of the Efficacy between First-Line Treatment Regimens for Patients with Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer

Autor: Kwang Hyun Choi, Chan Sub Park, Sang Hee Kim, Na Won Kim, Ju Hyeon Lee, Ji Yea Kim, In Chul Park, Min Ki Seong, Hyun-Ah Kim, Woo Chul Noh

Publikováno v: Journal of Breast Disease. 9:65-70

Purpose: Endocrine therapy is the first-line treatment recommended for patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer without visceral crisis. However, this recommendati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4298ac2cb81ebdc3f1cdad7b8f638a19
https://doi.org/10.14449/jbd.2021.9.2.65

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Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic

Autor: Ha Hee Jin, Jeewoo Lee, Timothy E. Esch, Ho Shin Kim, Noe A. Turcios, Kwang-Hyun Choi, Hee Kim, Larry V. Pearce, Minseok Kim, Shivaji A. Thorat, Peter M. Blumberg, Young Ho Kim, Jihyae Ann, Sun Wook Hwang

Publikováno v: Journal of Medicinal Chemistry. 63:418-424

Paradoxically, some TRPV1 agonists are, at the organismal level, both nonpungent and clinically useful as topical analgesics. Here, we describe the scaled-up synthesis and characterization in mouse models of a novel, nonpungent vanilloid. Potent anal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92d7ff93acb00695c9d8c15da9ca695
https://doi.org/10.1021/acs.jmedchem.9b01046

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Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a β-Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer’s Disease

Autor: Hyae Jung Hyun, Dong Wook Kang, Young Ho Kim, Jeewoo Lee, Jiyoun Lee, Joon Hwan Lee, Hyun-Seok Hong, Dong-Gyu Jo, Jin-Mi Kang, Kwang-Hyun Choi, Hee-Jin Ha, Hee Kim, Sae Hee Kim, Hyuk-Min Kim, Jihyae Ann

Publikováno v: Journal of Medicinal Chemistry. 61:396-402

We developed an orally active and blood-brain-barrier-permeable benzofuran analogue (8, MDR-1339) with potent antiaggregation activity. Compound 8 restored cellular viability from Aβ-induced cytotoxicity but also improved the learning and memory fun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a6f861e3cec0558933b6c9e180406e
https://doi.org/10.1021/acs.jmedchem.7b00844

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Self-Assembled Dendritic Pt Nanostructure with High-Index Facets as Highly Active and Durable Electrocatalyst for Oxygen Reduction

Autor: Dong Young Chung, Kwang-Hyun Choi, Youngjin Jang, Yung-Eun Sung, Ji Eun Lee, Namgee Jung

Publikováno v: ChemSusChem. 10:3063-3068

The durability issues of Pt catalyst should be resolved for the commercialization of proton exchange membrane fuel cells. Nanocrystal structures with high-index facets have been recently explored to solve the critical durability problem of fuel cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6cb5d7f8345f7a3a6c34f7e5460bb1
https://doi.org/10.1002/cssc.201700852

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Increased risk of comorbid rheumatic disorders in vitiligo patients: A nationwide population-based study

Autor: Chong Won Choi, Kwang Hyun Choi, Jung Min Bae, Sung Hye Eun

Publikováno v: The Journal of Dermatology. 44:909-913

Vitiligo is a common acquired depigmentation disorder. Previous studies have shown that vitiligo is associated with a variety of autoimmune disorders. However, a large-scale epidemiological study focused on comorbid rheumatic disorders has not been u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e4a67cdefe0d4c9856ef3f0a67147c
https://doi.org/10.1111/1346-8138.13846

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Inflammatory bowel disease is associated with an increased risk of inflammatory skin diseases: A population-based cross-sectional study

Autor: Young Bok Lee, Hyun Jeong Park, Miri Kim, Kwang Hyun Choi, Se Won Hwang, Jung Min Bae

Publikováno v: Journal of the American Academy of Dermatology. 76:40-48

Background Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract attributed to aberrant activity of the immune system. Increasing evidence suggests that patients with IBD are at an increased risk of inflammatory skin dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e9eebda747832752e525dfee1ba829
https://doi.org/10.1016/j.jaad.2016.08.022

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Hidden Pictures of Kaposi's Sarcoma in Psoriatic Lesions: A Diagnostic Challenge

Autor: Jisook Yoo, Kwang-Hyun Choi, Mihn-Sook Jue, Mingyul Jo, Hyang-Joon Park, Min-Soo Kim

Publikováno v: Annals of Dermatology

Kaposi's sarcoma is a multifocal proliferative vascular tumor involving the skin and other organ and psoriasis is a chronic cutaneous disease with papules and plaques with white scale. Development of Kaposi's sarcoma in psoriasis patients has been re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d4c4c63b7b6744b2a56ea90c11e9b7
http://europepmc.org/articles/PMC5125957

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