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Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
BackgroundObesity is known to increase the risk and severity of age-related macular degeneration (AMD). Increased inflamed metabolic activity of visceral adipose tissue (VAT) is considered as a crucial underlying mechanism for the harmful effects of
Externí odkaz:
https://doaj.org/article/d79ce09f47f64235a367abf9911898a9
Autor:
Seongkwang Cha, Kwang-Eon Choi, Jungryul Ahn, Minsu Yoo, Yurim Jeong, Seong-Woo Kim, Yong Sook Goo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Retinal prosthesis is regarded as the treatment for vision restoration in the blind with retinal degeneration (RD) due to the loss of photoreceptors. A strategy for retinal prosthesis is to electrically activate surviving neurons. The retina
Externí odkaz:
https://doaj.org/article/ad9403b056cd48a6ab702abe9ab27ed4
Autor:
Seongkwang Cha, Jungryul Ahn, Seong-Woo Kim, Kwang-Eon Choi, Yongseok Yoo, Heejong Eom, Donggwan Shin, Yong Sook Goo
Publikováno v:
Bioengineering, Vol 10, Iss 10, p 1135 (2023)
This study aims to investigate the efficacy of electrical stimulation by comparing network-mediated RGC responses in normal and degenerate retinas using a N-methyl-N-nitrosourea (MNU)-induced non-human primate (NHPs) retinitis pigmentosa (RP) model.
Externí odkaz:
https://doaj.org/article/3faee583bc1f4c4faa8a8ecaf45ce398
Autor:
Que Anh Vu, Hee Won Seo, Kwang-Eon Choi, Namju Kim, Yoo Na Kang, Jaemeun Lee, Sun-Hyun Park, Jee Taek Kim, Sohee Kim, Seong-Woo Kim
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The retinal structural changes after subretinal implantation of three-dimensional (3D) microelectrodes were investigated in a mini pig. Three types of electrode were implanted into the subretinal spaces of nine mini pigs: 75-μm-high 3D electrodes on
Externí odkaz:
https://doaj.org/article/a9ef8c2d2ab6455dacf37e4bf45428a7
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Retinal prostheses have shown some clinical success in patients with retinitis pigmentosa and age-related macular degeneration. However, even after the implantation of a retinal prosthesis, the patient’s visual acuity is at best less than 20/420. R
Externí odkaz:
https://doaj.org/article/2a8730d0fd684c1d89dde7ade94055b0
Autor:
Kwang-Eon Choi, Vu Thi Que Anh, Jee Taek Kim, Cheolmin Yun, Seongkwang Cha, Jungryul Ahn, Yong Sook Goo, Seong-Woo Kim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract We aimed to develop an outer retinal degeneration pig model induced by temporary intravitreal loading of N-methyl-N-nitrosourea (MNU) during vitrectomy. In a preliminary experiment involving 5 mini-pig cases to determine the appropriate conc
Externí odkaz:
https://doaj.org/article/07c28e1fa9984f568fb83ace3ef4960a
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract We aimed to investigate the clinical implication of suspended scattering particles in motion (SSPiM) using optical coherence tomography angiography (OCTA) among branch retinal vein occlusion disease (BRVO) cases with macular edema (ME). Medi
Externí odkaz:
https://doaj.org/article/b78823690f3947eaa470a79a251ad345
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract We aimed to evaluate the relationship between the capillary abnormalities including nonperfusion area (NPA) in optical coherence tomography angiography (OCTA) images and the recurrence of macular edema (ME) secondary to branch retinal vein o
Externí odkaz:
https://doaj.org/article/6cd05e7288a147e98987f896357769df