Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Kwang Woon Kim"'
Autor:
Rustin R. Lovewell, Junshik Hong, Subhadip Kundu, Carly M. Fielder, Qianni Hu, Kwang Woon Kim, Haley E. Ramsey, Agnieszka E. Gorska, Londa S. Fuller, Linjie Tian, Priyanka Kothari, Ana Paucarmayta, Emily F. Mason, Ingrid Meza, Yanira Manzanarez, Jason Bosiacki, Karla Maloveste, Ngan Mitchell, Emilia A. Barbu, Aaron Morawski, Sebastien Maloveste, Zac Cusumano, Shashank J. Patel, Michael R. Savona, Solomon Langermann, Han Myint, Dallas B. Flies, Tae Kon Kim
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
Effective eradication of leukemic stem cells (LSCs) remains the greatest challenge in treating acute myeloid leukemia (AML). The immune receptor LAIR-1 has been shown to regulate LSC survival; however, the therapeutic potential of this pathway remain
Externí odkaz:
https://doaj.org/article/4400206aba4d473a88839c90e119c65a
Autor:
Pritha Paul, Jingbo Qiao, Kwang Woon Kim, Carmelle Romain, Sora Lee, Natasha Volny, Bret Mobley, Hernan Correa, Dai H Chung
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72570 (2013)
We have previously demonstrated the role of gastrin-releasing peptide (GRP) as an autocrine growth factor for neuroblastoma. Here, we report that GRP silencing regulates cell signaling involved in the invasion-metastasis cascade. Using a doxycycline
Externí odkaz:
https://doaj.org/article/9036e26896e7452a82ee13e5efea0bc2
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2275 (2008)
Lung cancer remains the leading cause of cancer death worldwide. Radioresistance of lung cancer cells results in unacceptable rate of loco-regional failure. Although radiation is known to induce apoptosis, our recent study showed that knockdown of pr
Externí odkaz:
https://doaj.org/article/1e9ea9257eaf4e69ab7f6742f55b2186
Despite recent advances in the management of breast and lung cancer, novel treatment strategies are still needed to further improve patient outcome. The targeting of cell death pathways has therefore been proposed to enhance therapeutic ratio in canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299236ca3908ccbbdc0bf92fe007aff0
https://doi.org/10.1158/1535-7163.c.6532034
https://doi.org/10.1158/1535-7163.c.6532034
Supplementary Fig. S1 from Radiosensitization of solid tumors by Z-VAD, a pan-caspase inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177ec806b4e6ba517fe8518bdd24c8b8
https://doi.org/10.1158/1535-7163.22485632
https://doi.org/10.1158/1535-7163.22485632
Publikováno v:
Oncoscience
MicroRNA-145 (miR-145) plays a suppressive role in the process of tumorigenesis and an important role in induction of autophagy. However, the exact role of miR-145 in therapeutically resistant neuroblastoma cells remain elusive. Herein, we sought to
Autor:
Hernan Correa, Kwang Woon Kim, Rachael A. Clark, Julia Y. Kim, Dai H. Chung, Jingbo Qiao, Camille M. Powers
Publikováno v:
Oncotarget
Neuroblastoma remains one of the most difficult pediatric solid tumors to treat. In particular, the refractory and relapsing neuroblastomas are highly heterogeneous with diverse molecular profiles. We previously demonstrated that AKT2 plays critical
Autor:
Shashank Patel, Ana Paucarmayta, Junshik Hong, Ron Copeland, Karla Maloveste, Tae Kon Kim, Carly Hedgepath, Rustin Lovewell, Linda N. Liu, Han Myint, Linjie Tian, Kwang Woon Kim, Thomas O'Neill, Dallas B. Flies, Solomon Langermann
Publikováno v:
Blood. 138:3413-3413
Extensive research has led to recent approval of novel therapies such as mylotarg, venetoclax, glasdegib and CC486, and small molecule inhibitors against actionable mutations such as ivosidenib (IDH1), enasidenib (IDH2), gliteritinib and midostaurin
Autor:
Hyun Soo Kim, Kwang-Woon Kim
Publikováno v:
Journal of the Preventive Veterinary Medicine. 41:66-70
Autor:
Camille M. Powers, Jingbo Qiao, Dai H. Chung, Kwang Woon Kim, Sora Lee, Hernan Correa, Eric J. Rellinger
Publikováno v:
Oncotarget
The lost expression of α-catenin has been found in cancers, and reinstalling α-catenin inhibits tumor growth. Here we hypothesized that the α-N-catenin, a homologous member of α-catenin and neural-specific expressed, functions as a novel tumor su