Zobrazeno 1 - 10
of 630
pro vyhledávání: '"Kwang Sik Kim"'
Autor:
Taewoon Kim, Harshitha Kallubhavi Choodinatha, Kwang Sik Kim, Kyusoon Shin, Hyeon Ji Kim, Jee Yoon Park, Jong Wook Hong, Luke P. Lee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Preeclampsia is a hypertensive disorder of pregnancy that can lead to stillbirth and preterm birth if not treated promptly. Currently, the diagnosis of preeclampsia relies on clinical symptoms such as hypertension and proteinuria, along with
Externí odkaz:
https://doaj.org/article/fcc2478748fc4512968862591e50cbbf
Autor:
Hae Jin Park, Young Seok Kim, Young Hoon Lee, Sung Hwan Hong, Kwang Sik Kim, Young Koon Park, Ki Buem Kim
Publikováno v:
Journal of Materials Research and Technology, Vol 15, Iss , Pp 572-581 (2021)
The objective of the present study was to investigate some transition metal nitride to determine the relationship between microstructural evolution and mechanical properties such as hardness and adhesion strength of the hard coating. Results showed t
Externí odkaz:
https://doaj.org/article/29a30845523549109701edb0d6a07634
Autor:
Hao Sun, Xuehua Wan, Yu Fan, Peng Liu, Yajun Song, Ningyu Zhu, Zhifeng Duan, Qian Wang, Fang Chen, Changhong Zhou, Yangyang Zheng, Peng Ding, Fenxia Liu, Lu Feng, Kwang Sik Kim, Lei Wang
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111033- (2022)
Summary: The immune response of brain cells to invading bacteria in vivo and the mechanism used by pathogenic bacteria to escape brain immune surveillance remain largely unknown. It is believed that microglia eliminate bacteria by phagocytosis based
Externí odkaz:
https://doaj.org/article/d6543e4012054f5e89d893da503da0e1
Autor:
Noor Akbar, Ruqaiyyah Siddiqui, Mazhar Iqbal, Kuppusamy Sagathevan, Kwang Sik Kim, Fazal Habib, Naveed Ahmed Khan
Publikováno v:
ACS Omega, Vol 6, Iss 18, Pp 12261-12273 (2021)
Externí odkaz:
https://doaj.org/article/39f1cc8ca57241c6a52709890526c9a2
Autor:
Rui-Cheng Yang, Xin-Yi Qu, Si-Yu Xiao, Liang Li, Bo-Jie Xu, Ji-Yang Fu, Yu-Jin Lv, Nouman Amjad, Chen Tan, Kwang Sik Kim, Huan-Chun Chen, Xiang-Ru Wang
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Background Blood-brain barrier (BBB) disruption and neuroinflammation are considered key mechanisms of pathogenic Escherichia coli invasion of the brain. However, the specific molecules involved in meningitic E. coli-induced BBB breakdown an
Externí odkaz:
https://doaj.org/article/ce2f7ec3022b4a02971eeb191791e5a8
Autor:
Guan-Da Syu, Shih-Chin Wang, Guangzhong Ma, Shuang Liu, Donna Pearce, Atish Prakash, Brandon Henson, Lien-Chun Weng, Devlina Ghosh, Pedro Ramos, Daniel Eichinger, Ignacio Pino, Xinzhong Dong, Jie Xiao, Shaopeng Wang, Nongjian Tao, Kwang Sik Kim, Prashant J. Desai, Heng Zhu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
G protein-coupled receptors (GPCRs) are important targets for drug discovery. Here, the authors develop a Virion Display array of 315 functional non-odorant GPCRs, providing a platform for high-throughput, unbiased screening for small molecule drugs,
Externí odkaz:
https://doaj.org/article/7a853ae4a1c340a6a212e52e60b8d905
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Trypanosoma cruzi (T. cruzi), the etiological agent of Chagas Disease (CD), is transmitted to humans by infected kissing bugs, blood transfusion, organ transplantation, and from mother-to-child. Congenital transmission is now considered an important
Externí odkaz:
https://doaj.org/article/06ed48e144f64e0f8cdcc0f0af593218
Autor:
Ningyu Zhu, Chengxian Zhang, Atish Prakash, Zheng Hou, Wei Liu, Weifeng She, Andrew Morris, Kwang Sik Kim
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 3, Pp n/a-n/a (2021)
Abstract Group B Streptococcus (GBS) remains the most common Gram‐positive bacterium causing neonatal meningitis and GBS meningitis continues to be an important cause of mortality and morbidity. In this study, we showed that GBS penetration into th
Externí odkaz:
https://doaj.org/article/35a58a3fe62f43c8acac869a2c9514a6
Autor:
Hideyuki Takahashi, Naoshi Dohmae, Kwang Sik Kim, Ken Shimuta, Makoto Ohnishi, Shigeyuki Yokoyama, Tatsuo Yanagisawa
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237883 (2020)
Although whole-genome sequencing has provided novel insights into Neisseria meningitidis, many open reading frames have only been annotated as hypothetical proteins with unknown biological functions. Our previous genetic analyses revealed that the hy
Externí odkaz:
https://doaj.org/article/38bb7f8def9349f98e66b4b48f552806
Autor:
Wei-Dong Zhao, Dong-Xin Liu, Jia-Yi Wei, Zi-Wei Miao, Ke Zhang, Zheng-Kang Su, Xue-Wei Zhang, Qiang Li, Wen-Gang Fang, Xiao-Xue Qin, De-Shu Shang, Bo Li, Qing-Chang Li, Liu Cao, Kwang Sik Kim, Yu-Hua Chen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Penetration of the blood–brain barrier (BBB) is crucial for development of E. coli-caused meningitis. Here, the authors show that a host membrane protein, Caspr1, acts as a receptor for a bacterial virulence factor to facilitate BBB penetration and
Externí odkaz:
https://doaj.org/article/2284a8655d2b415395c6982bdf49525d