Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Kwang Bo Jung"'
Autor:
Eun-Jung Kang, Jae-Hoon Kim, Young Eun Kim, Hana Lee, Kwang Bo Jung, Dong-Ho Chang, Youngjin Lee, Shinhye Park, Eun-Young Lee, Eun-Ji Lee, Ho Bum Kang, Moon-Young Rhyoo, Seungwoo Seo, Sohee Park, Yubin Huh, Jun Go, Jung Hyeon Choi, Young-Keun Choi, In-Bok Lee, Dong-Hee Choi, Yun Jeong Seo, Jung-Ran Noh, Kyoung-Shim Kim, Jung Hwan Hwang, Ji-Seon Jeong, Ha-Jeong Kwon, Hee Min Yoo, Mi-Young Son, Yeon-Gu Kim, Dae-Hee Lee, Tae-Young Kim, Hyo-Jung Kwon, Myung Hee Kim, Byoung-Chan Kim, Yong-Hoon Kim, Dukjin Kang, Chul-Ho Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Akkermansia muciniphila has received great attention because of its beneficial roles in gut health by regulating gut immunity, promoting intestinal epithelial development, and improving barrier integrity. However, A. muciniphila-derived func
Externí odkaz:
https://doaj.org/article/561797eb415d4717ac55e900e1272c33
Autor:
Ohman Kwon, Hana Lee, Jaeeun Jung, Ye Seul Son, Sojeong Jeon, Won Dong Yoo, Naeun Son, Kwang Bo Jung, Eunho Choi, In-Chul Lee, Hyung-Jun Kwon, Chuna Kim, Mi-Ok Lee, Hyun-Soo Cho, Dae Soo Kim, Mi-Young Son
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Three-dimensional human intestinal organoids (hIO) are widely used as a platform for biological and biomedical research. However, reproducibility and challenges for large-scale expansion limit their applicability. Here, we establish a human
Externí odkaz:
https://doaj.org/article/6f5d70098bfd4eaabe1920746c0323fc
Autor:
Hana Lee, Kwang Bo Jung, Ohman Kwon, Ye Seul Son, Eunho Choi, Won Dong Yu, Naeun Son, Jun Hyoung Jeon, Hana Jo, Haneol Yang, Yeong Rak Son, Chan-Seok Yun, Hyun-Soo Cho, Sang Kyu Kim, Dae-Soo Kim, Doo-Sang Park, Mi-Young Son
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Little is known about the modulatory capacity of the microbiota in early intestinal development. We examined various intestinal models that respond to gut microbial metabolites based on human pluripotent stem cell-derived human intestinal organoids (
Externí odkaz:
https://doaj.org/article/bcedc8c3adae41f9bf2188ec7de1d48b
Autor:
Mi-Ok Lee, Su-gi Lee, Cho-Rok Jung, Ye Seul Son, Jae-Woon Ryu, Kwang Bo Jung, Jun-Ho Ahn, Jung-Hwa Oh, Hyang-Ae Lee, Jung Hwa Lim, Janghwan Kim, Insu Jang, Jinhyuk Choi, Jaeeun Jung, Kunhyang Park, Byungwook Lee, Dae-Soo Kim, Mi-Young Son, Hyun-Soo Cho
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Quantitative methods to assess the quality of hPSC-derived organoids have not been developed. Here they present a prediction algorithm to assess the transcriptomic similarity between hPSC-derived organoids and the corresponding human target organs an
Externí odkaz:
https://doaj.org/article/27708e935ee5482783e2d1c6359a3d60
Next-Generation Intestinal Toxicity Model of Human Embryonic Stem Cell-Derived Enterocyte-Like Cells
Autor:
Bokyeong Ryu, Mi-Young Son, Kwang Bo Jung, Ukjin Kim, Jin Kim, Ohman Kwon, Ye Seul Son, Cho-Rok Jung, Jae-Hak Park, C-Yoon Kim
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
The gastrointestinal tract is the most common exposure route of xenobiotics, and intestinal toxicity can result in systemic toxicity in most cases. It is important to develop intestinal toxicity assays mimicking the human system; thus, stem cells are
Externí odkaz:
https://doaj.org/article/2203e98e98fd415eac74a9e467ee6a44
Autor:
Minhyung Lee, Jeongmin Ha, Ye Seul Son, Hyunjun Ahn, Kwang Bo Jung, Mi-Young Son, Janghwan Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 7, Pp 1-12 (2019)
Stem cells: Cleaner generation by selective killing Using genetic engineering to convert cells into stem cells without leaving unwanted foreign DNA behind is made easier and more effective by a method that allows cells acquiring unwanted DNA to be se
Externí odkaz:
https://doaj.org/article/9e6fd6ce20d747c287f27d24bd04e418
Autor:
Mi-Ok Lee, Kwang Bo Jung, Seong-Jae Jo, Sung-Ae Hyun, Kyoung-Sik Moon, Joung-Wook Seo, Sang-Heon Kim, Mi-Young Son
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-17 (2019)
Abstract Background Cardiac fibrosis is the most common pathway of many cardiac diseases. To date, there has been no suitable in vitro cardiac fibrosis model that could sufficiently mimic the complex environment of the human heart. Here, a three-dime
Externí odkaz:
https://doaj.org/article/8b166fb48b1f48e3a935946d0fc701ed
Autor:
Kwang Bo Jung, Hana Lee, Ye Seul Son, Mi-Ok Lee, Young-Dae Kim, Soo Jin Oh, Ohman Kwon, Sunwha Cho, Hyun-Soo Cho, Dae-Soo Kim, Jung-Hwa Oh, Matthias Zilbauer, Jeong-Ki Min, Cho-Rok Jung, Janghwan Kim, Mi-Young Son
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Human pluripotent stem cell-derived intestinal organoids (hIOs) are a useful model with which to study intestinal development and disease, but they require in vivo maturation to resemble adult tissue. Here, the authors show that T lymphocyte-derived
Externí odkaz:
https://doaj.org/article/a475745ef0d7496ba465e8488bf0de6b
Autor:
Kwang Bo Jung, Ohman Kwon, Mi-Ok Lee, Hana Lee, Ye Seul Son, Omer Habib, Jung-Hwa Oh, Hyun-Soo Cho, Cho-Rok Jung, Janghwan Kim, Mi-Young Son
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 7, p 976 (2019)
Human intestinal organoids (hIOs), which resemble the human intestine structurally and physiologically, have emerged as a new modality for the study of the molecular and cellular biology of the intestine in vitro. We recently developed an in vitro ma
Externí odkaz:
https://doaj.org/article/bba33a4d7fac4edda70f67f16b2510aa
Publikováno v:
International Journal of Stem Cells. 15:104-111
Many of early findings regarding intestinal stem cells (ISCs) and their niche in the human intestine have relied on colorectal cancer cell lines and labor-intensive and time-consuming mouse models. However, these models cannot accurately recapitulate