Zobrazeno 1 - 10
of 522
pro vyhledávání: '"Kwan-Kyu Park"'
Autor:
Mi-Gyeong Gwon, Jaechan Leem, Hyun-Jin An, Hyemin Gu, Seongjae Bae, Jong Hyun Kim, Kwan-Kyu Park
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102036- (2023)
Atopic dermatitis (AD) is a common inflammatory skin disease caused by an immune disorder. Mast cells are known to be activated and granulated to maintain an allergic reaction, including rhinitis, asthma, and AD. Although hypoxia-inducible factor-1 a
Externí odkaz:
https://doaj.org/article/8fa66ff47c004a729309793f16b22a9f
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 1, Pp 337-352 (2023)
Obstructive uropathy is a clinical condition that can lead to chronic kidney disease. However, treatments that can prevent the progression of renal injury and fibrosis are limited. Farrerol (FA) is a natural flavone with potent antioxidant and anti-i
Externí odkaz:
https://doaj.org/article/d4f0dc0ae1454a38bb1d4e7e07748b16
Autor:
Hye Jin Choi, Young-Ah Kim, Junghwa Ryu, Kwan-Kyu Park, Sun-Jae Lee, Byung Seok Kim, Jeong-En Song, Joo Dong Kim
Publikováno v:
Molecules, Vol 29, Iss 3, p 593 (2024)
Liver damage caused by various factors results in fibrosis and inflammation, leading to cirrhosis and cancer. Fibrosis results in the accumulation of extracellular matrix components. The role of STAT proteins in mediating liver inflammation and fibro
Externí odkaz:
https://doaj.org/article/266c0b0d04ab4695a9cd66b24aca7501
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1858 (2022)
Acne vulgaris has a pathogenesis that involves increased sebum production and perifollicular inflammation. Sterol regulatory element-binding protein-1 (SREBP-1) and peroxisome proliferator activated receptor-γ (PPAR-γ) are transcription factors tha
Externí odkaz:
https://doaj.org/article/24a9c69aa50f4a47996dc71be469acba
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15255 (2022)
Parkinson’s disease (PD), a neurodegenerative disorder, is characterized by the loss of dopaminergic (DA) neurons. The pathogenesis of PD is associated with several factors including oxidative stress, inflammation, and mitochondrial dysfunction. Ca
Externí odkaz:
https://doaj.org/article/494813637f764fa4af4a7f59da9a69e7
Autor:
Seongjae Bae, Hyemin Gu, Mi-Gyeong Gwon, Hyun-Jin An, Sang-Mi Han, Sun-Jae Lee, Jaechan Leem, Kwan-Kyu Park
Publikováno v:
Toxins, Vol 14, Iss 10, p 663 (2022)
Streptococcus pyogenes (S. pyogenes) bacteria cause almost all primary skin infections in humans. Bee venom (BV) and melittin (Mel) have multiple effects, including antibacterial and anti-inflammatory activities. This study aims to demonstrate their
Externí odkaz:
https://doaj.org/article/e84adb4d7e59401da64ad134b7bf3436
Autor:
Young-Ah Kim, Hyemin Gu, Mi-Gyeong Gwon, Hyun-Jin An, Seongjae Bae, Jaechan Leem, Hyun Jin Jung, Kwan-Kyu Park, Sun-Jae Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11365 (2022)
The global burden of chronic kidney disease is increasing, and the majority of these diseases are progressive. Special site-targeted drugs are emerging as alternatives to traditional drugs. Oligonucleotides (ODNs) have been proposed as effective ther
Externí odkaz:
https://doaj.org/article/6821ef10c52b4c9cb800b257ed44a13c
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8138 (2022)
Despite emerging evidence suggesting that autophagy occurs during renal interstitial fibrosis, the role of autophagy activation in fibrosis and the mechanism by which autophagy influences fibrosis remain controversial. Transcription factor EB (TFEB)
Externí odkaz:
https://doaj.org/article/1f9edb164889488db0656820e3688941
Autor:
Hyemin Gu, Hyun-Jin An, Mi-Gyeong Gwon, Seongjae Bae, Jaechan Leem, Sun-Jae Lee, Sang-Mi Han, Christos C. Zouboulis, Kwan-Kyu Park
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3152 (2022)
Acne vulgaris is the most common disease of the pilosebaceous unit. The pathogenesis of this disease is complex, involving increased sebum production and perifollicular inflammation. Understanding the factors that regulate sebum production is importa
Externí odkaz:
https://doaj.org/article/9c506e36dc8c430b9cd3714897f61e93
Autor:
Hyun Jin Jung, Hyun-Jin An, Mi-Gyeong Gwon, Hyemin Gu, Seongjae Bae, Sun-Jae Lee, Young-Ah Kim, Jaechan Leem, Kwan-Kyu Park
Publikováno v:
Molecules, Vol 27, Iss 3, p 766 (2022)
Renal fibrosis is a common process of various kidney diseases. Autophagy is an important cell biology process to maintain cellular homeostasis. In addition, autophagy is involved in the pathogenesis of various renal disease, including acute kidney in
Externí odkaz:
https://doaj.org/article/0779417623ac4fab90d73ff59372b3ee