Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kwan-Hyun Kim"'
Autor:
Abbas Raza, Wei Xie, Kwan-Hyun Kim, Venkateshwara Rao Dronamraju, Jessica Williams, Robert Vince, Swati S. More
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1075 (2022)
Supplementation of glutathione (GSH) levels through varying formulations or precursors has thus far appeared to be a tenable strategy to ameliorate disease-associated oxidative stress. Metabolic liability of GSH and its precursors, i.e., hydrolysis b
Externí odkaz:
https://doaj.org/article/54b235de56224df7a0b4e8cc4ea57df8
Autor:
Sung-Soo Park, Jong Cheol Lee, Ja Min Byun, Gyucheol Choi, Kwan Hyun Kim, Sungwon Lim, David Dingli, Young-Woo Jeon, Seung-Ah Yahng, Seung-Hwan Shin, Chang-Ki Min, Jamin Koo
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Optimal first-line treatment that enables deeper and longer remission is crucially important for newly diagnosed multiple myeloma (NDMM). In this study, we developed the machine learning (ML) models predicting overall survival (OS) or respon
Externí odkaz:
https://doaj.org/article/2ad20115060f407b9e25380cf01c93b5
Autor:
Ariel Caride, Jin Sung Jang, Geng-Xian Shi, Sam Lenz, Jian Zhong, Kwan Hyun Kim, Mariet Allen, Keith D. Robertson, Gianrico Farrugia, Tamas Ordog, Nilüfer Ertekin-Taner, Jeong-Heon Lee
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Chromatin immunoprecipitation (ChIP) is an antibody-based approach that is frequently utilized in chromatin biology and epigenetics. The challenge in experimental variability by unpredictable nature of usable input amounts from samples and u
Externí odkaz:
https://doaj.org/article/233f4c97b89d44f49f48f10054c79ef8
Autor:
Leticia Sandoval, Wazim Mohammed Ismail, Amelia Mazzone, Mihai Dumbrava, Jenna Fernandez, Amik Munankarmy, Terra Lasho, Moritz Binder, Vernadette Simon, Kwan Hyun Kim, Nicholas Chia, Jeong-Heon Lee, S. John Weroha, Mrinal Patnaik, Alexandre Gaspar-Maia
Publikováno v:
Genes, Vol 14, Iss 6, p 1245 (2023)
The snATAC + snRNA platform allows epigenomic profiling of open chromatin and gene expression with single-cell resolution. The most critical assay step is to isolate high-quality nuclei to proceed with droplet-base single nuclei isolation and barcodi
Externí odkaz:
https://doaj.org/article/4a694eda71f04129943ec65ea0e8441e
Autor:
Gaspar-Maia, Leticia Sandoval, Wazim Mohammed Ismail, Amelia Mazzone, Mihai Dumbrava, Jenna Fernandez, Amik Munankarmy, Terra Lasho, Moritz Binder, Vernadette Simon, Kwan Hyun Kim, Nicholas Chia, Jeong-Heon Lee, S. John Weroha, Mrinal Patnaik, Alexandre
Publikováno v:
Genes; Volume 14; Issue 6; Pages: 1245
The snATAC + snRNA platform allows epigenomic profiling of open chromatin and gene expression with single-cell resolution. The most critical assay step is to isolate high-quality nuclei to proceed with droplet-base single nuclei isolation and barcodi
Autor:
Sung-Hoon Kim, Junxuan Lü, Shi Yong Ryu, Kwang-Seok Ahn, Eun-Ok Lee, Hyo-Jung Lee, Hyunsoo Bae, Kyoo-Seok Ahn, Kwan-Hyun Kim, Hyo-Jeong Lee, Yoonji Lee, Sun Choi, Jae-Ho Lee
Supplementary Figures 1-4 from Herbal Compound Farnesiferol C Exerts Antiangiogenic and Antitumor Activity and Targets Multiple Aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) Signaling Cascades
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0020baaf4e25b540cf8db80aa4bf1234
https://doi.org/10.1158/1535-7163.22486013.v1
https://doi.org/10.1158/1535-7163.22486013.v1
Autor:
Sung-Hoon Kim, Junxuan Lü, Shi Yong Ryu, Kwang-Seok Ahn, Eun-Ok Lee, Hyo-Jung Lee, Hyunsoo Bae, Kyoo-Seok Ahn, Kwan-Hyun Kim, Hyo-Jeong Lee, Yoonji Lee, Sun Choi, Jae-Ho Lee
Farnesiferol C (FC) is one of the major compounds isolated from Ferula assafoetida, an Asian herbal spice used for cancer treatment as a folk remedy. Here, we examined the hypothesis that novel antiangiogenic activities of FC contribute to anticancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cf8eda086a13677ee6ca13c6332cb6
https://doi.org/10.1158/1535-7163.c.6532187.v1
https://doi.org/10.1158/1535-7163.c.6532187.v1
Autor:
Moritz Binder, Terra L. Lasho, Wazim Mohammed Ismail, Nana A. Ben-Crentsil, Jenna A. Fernandez, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Susan M. Schwager, Jonathan J. Harington, Melissa R. Snyder, Nathalie M. Droin, Eric Solary, Keith D. Robertson, Eric D. Wieben, Eric Padron, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik
Coronavirus disease 2019 (COVID-19) is associated with significant morbidity and mortality, albeit with considerable heterogeneity among affected individuals. It remains unclear which factors determine severity of illness and long-term outcomes. Emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ea8e91a2ed17849d0a3de97470e93e1
https://doi.org/10.1101/2022.08.25.505316
https://doi.org/10.1101/2022.08.25.505316
Autor:
Moritz Binder, Terra L. Lasho, Wazim Mohammed Ismail, Nana A. Ben-Crentsil, Jenna A. Fernandez, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Susan M. Schwager, Jonathan J. Harrington, Melissa R. Snyder, Nathalie M. Droin, Eric Solary, Keith D. Robertson, Eric D. Wieben, Eric Padron, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik
Publikováno v:
Cancer Research. 83:806-806
Background: COVID-19 causes significant morbidity and mortality, albeit with considerable heterogeneity among affected individuals. It remains unclear which host factors determine disease severity and survival. Given the propensity of clonal hematopo
Publikováno v:
Chemical Research in Toxicology. 34:1355-1366
Diacetyl (DA), a food flavorant, is linked with occupational lung disease. Our in vitro experiments described the formation of a covalent adduct by DA with Arg5 of the Aβ1-42 peptide, which resulted in only a transient increase in neurotoxicity in S