Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kwan Ho Jung"'
Autor:
Baoxing Shen, Kwan Ho Jung, Songtao Ye, Conner A. Hoelzel, Charles H. Wolstenholme, He Huang, Yu Liu, Xin Zhang
Publikováno v:
Aggregate, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Aberrant protein aggregation leads to various human diseases, but little is known about the physical chemical properties of these aggregated proteins in cells. Herein, we developed a boron‐dipyrromethene (BODIPY)‐based HaloTag probe, who
Externí odkaz:
https://doaj.org/article/6465ea4efcff4be4a9c326a188a023b3
Publikováno v:
bioRxiv
RNA-binding proteins (RBPs) containing intrinsically disordered domains undergo liquid-liquid phase separation to form nuclear bodies under stress conditions. This process is also connected to the misfolding and aggregation of RBPs, which are associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da4eb6859a8540f86fec9e911402c54
https://europepmc.org/articles/PMC10153235/
https://europepmc.org/articles/PMC10153235/
Autor:
Baoxing Shen, Kwan Ho Jung, Songtao Ye, Conner A. Hoelzel, Charles H. Wolstenholme, He Huang, Yu Liu, Xin Zhang
Publikováno v:
Aggregate.
Autor:
Conner A. Hoelzel, Hang Hu, Charles H. Wolstenholme, Basel A. Karim, Kyle T. Munson, Kwan Ho Jung, Han Zhang, Yu Liu, Hemant P. Yennawar, John B. Asbury, Xiaosong Li, Xin Zhang
Publikováno v:
Angewandte Chemie. 132:4815-4822
Autor:
Hang Hu, Yu Liu, Charles H. Wolstenholme, Basel A. Karim, Kyle T. Munson, Conner A. Hoelzel, Hemant P. Yennawar, Han Zhang, Xin Zhang, Xiaosong Li, John B. Asbury, Kwan Ho Jung
Publikováno v:
Angewandte Chemie International Edition. 59:4785-4792
While organic donor-acceptor (D-A) molecules are widely employed in multiple areas, the application of more D-A molecules could be limited because of an inherent polarity sensitivity that inhibits photochemical processes. Presented here is a facile c
Autor:
Kwan Ho, Jung, Xin, Zhang
Publikováno v:
Methods in enzymology. 639
Protein aggregation is a process that occurs through the self-assembly of misfolded proteins to form soluble oligomers and insoluble aggregates. While there has been significant interest in protein aggregation for neurodegenerative diseases, progress
Autor:
Kwan Ho Jung, Xin Zhang
Protein aggregation is a process that occurs through the self-assembly of misfolded proteins to form soluble oligomers and insoluble aggregates. While there has been significant interest in protein aggregation for neurodegenerative diseases, progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::140db3f98d414915c7c7bfa97380d012
https://doi.org/10.1016/bs.mie.2020.04.006
https://doi.org/10.1016/bs.mie.2020.04.006
Publikováno v:
New Journal of Chemistry. 42:18143-18151
It is still a significant challenge to synthesize ratiometric fluorescent probes for Cd2+ ions in aqueous solutions and biosamples. In the present study, we synthesized a fluorescent peptidyl probe (1, pyrene-Cys-Gly-Pro-Cys-OH) based on a Cd2+-trigg
Publikováno v:
Chembiochem : a European journal of chemical biology. 20(8)
Protein aggregation involves the assembly of partially misfolded proteins into oligomeric and higher-order structures that have been associated with several neurodegenerative diseases. However, numerous questions relating to protein aggregation remai
Autor:
Leeann S. Grainger, Charles H. Wolstenholme, Xin Zhang, Anna Hou, Yu Liu, Matthew Fares, Kwan Ho Jung
Publikováno v:
Organicbiomolecular chemistry. 17(7)
Self-labelling protein tags with fluorogenic probes serve as great fluorescence imaging tools to understand key questions of protein dynamics and functions in living cells. In the present study, we report a SNAP-tag fluorogenic probe 4c mimicking the