Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kwan E. Kim"'
Publikováno v:
American Journal of Hypertension. 15:A178
Autor:
Kwan E. Kim, Charles Swartz
Publikováno v:
American Journal of Hypertension. 13:S300
Autor:
Kurosh Sharif, David T. Lowenthal, Alan Meyer, Bonita Falkner, Kwan E. Kim, Melton B. Affrime
Publikováno v:
Chest. 83:386-390
Previous studies have reported a therapeutic window of 0.8 to 2.0 ng/ml within which clonidine exerts its antihypertensive effect. This study was designed to investigate whether there was any loss of blood pressure control when plasma clonidine conce
Long-Term Clinical Effects, Bioavailability, and Kinetics of Minoxidil in Relation to Renal Function
Autor:
Gaddo Onesti, David T. Lowenthal, Eduardo W. Martinez, Jane Shirk, Kwan E. Kim, Patricia Busby, Robert Mutterperl, Melton Apfrime, Charles Swartz
Publikováno v:
The Journal of Clinical Pharmacology. 18:500-508
Minoxidil was used to treat 26 patients (17 to 67 years old) with severe hypertension and varying degrees of renal function. Our object was to assess long-term clinical efficacy, kinetics (acute and chronic), and bioavailability of minoxidil in chron
Autor:
Charles Swartz, David T. Lowenthal, Kwan E. Kim, Patricia Busby, Gaddo Onesti, John J. Schrogie, Melton B. Affrime
Publikováno v:
The Journal of Clinical Pharmacology. 18:414-424
A phase I dose-response study of 2-aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol HCl (MK-447) was performed with the following oral doses: 6.25, 12.5, 25, 50, and 100 mg. Each volunteer served as his own control. The study was carried out in double-
Publikováno v:
Postgraduate Medicine. 40:327-336
The patterns of renal function in renal parenchymal and renovascular hypertension are considered. In hypertension due to polycystic kidney disease the pattern indicates a proportional decrease of renal blood flow and of glomerular filtration rate. In
Autor:
Saul Mendelssohn, Kwan E. Kim, Albert N. Brest, Charles Swartz, Jose L. Cangiano, Robert H. Seller
Publikováno v:
American Heart Journal. 79:57-68
Four patients with digitalis toxicity were found to be hypomagnesemic and normokalemic. A significantly lower mean serum magnesium was noted in a group of digitalized heart failure patients (1.40 mEq./L.) than in matched normal subjects (1.93 mEq./L.
Autor:
Charles Swartz, Robert H. Seller, Martin S. Neff, Kwan E. Kim, Saul Mendelssohn, Stanley Banach
Publikováno v:
The American Journal of Cardiology. 29:377-382
This study was undertaken to evaluate the mechanism of the antiarrhythmic effect of magnesium sulfate in digitalis toxicity. The egress of potassium from the myocardium after the administration of 1 mg of acetyl strophanthidin into the right atrium w
Publikováno v:
BMJ. 4:11-14
To determine the validity of endogenous creatinine clearance as a measure of glomerular filtration rate in patients with renal disease 308 simultaneous determinations of inulin clearance and endogenous creatinine clearance were reviewed and analysed.
Autor:
Charles Swartz, Patricia Busby, Joseph M. Pitone, John Nancarrow, Kwan E. Kim, Melton B. Affrime, Gaddo Onesti, Jane Shirk, David T. Lowenthal
Publikováno v:
Clinical pharmacology and therapeutics. 23(5)
A single-dose kinetic study of oral timolol, 20 mg, was undertaken in 3 groups of volunteers with varying degrees of renal function--(1) 10 normal subjects (N); (2) 9 patients with moderate chronic renal insufficiency (MCRI; C cr, 20 to 50 ml/min); (