Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kwame Amaning"'
Autor:
Jidong Zhang, Christine Lair, Christine Roubert, Kwame Amaning, María Belén Barrio, Yannick Benedetti, Zhicheng Cui, Zhongliang Xing, Xiaojun Li, Scott G. Franzblau, Nicolas Baurin, Florence Bordon-Pallier, Cathy Cantalloube, Stephanie Sans, Sandra Silve, Isabelle Blanc, Laurent Fraisse, Alexey Rak, Lasse B. Jenner, Gulnara Yusupova, Marat Yusupov, Junjie Zhang, Takushi Kaneko, T.J. Yang, Nader Fotouhi, Eric Nuermberger, Sandeep Tyagi, Fabrice Betoudji, Anna Upton, James C. Sacchettini, Sophie Lagrange
Publikováno v:
Cell. 186:1013-1025.e24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e45831acf54d672d5d43fbfea84a5e9
https://doi.org/10.1016/j.cell.2023.01.043
https://doi.org/10.1016/j.cell.2023.01.043
Autor:
François Vallée, Philipp Baaske, Melanie Maschberger, Valerie Steier, Kwame Amaning, Pawel Linke, Stefan Duhr, Alexey Rak, Dennis Breitsprecher
Publikováno v:
Journal of Biomolecular Screening
Fragment-based lead discovery has proved to be an effective alternative to high-throughput screenings in identifying chemical matter that can be developed into robust lead compounds. The search for optimal combinations of biophysical techniques that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccda5276ff3c3bca4802dc0c481fac35
https://doi.org/10.1177/1087057115618347
https://doi.org/10.1177/1087057115618347
Autor:
Gary Mccort, Sylvie Llopart, Cyrielle Andouche, François Vallée, Cécile Delorme, Frédéric Foucalt, Maryse Lowinski, Nathalie Derimay, Kwame Amaning, Nis Halland, Antonio Ugolini, Valerie Steier, Alexey Rak, Christophe Marcireau, Stephanie Vougier
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(12)
We report the analysis of an in-house fragment screening campaign for the oncology target MEK1. The application of virtual screening (VS) as a primary fragment screening approach, followed by biophysical validation using differential screening fluori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f721fd74acc7605759c2ba6c5e697493
https://pubmed.ncbi.nlm.nih.gov/23648182
https://pubmed.ncbi.nlm.nih.gov/23648182
Autor:
Mathieu, Magali, Steier, Valérie, Fassy, Florence, Delorme, Cécile, Papin, David, Genet, Bruno, Duffieux, Francis, Bertrand, Thomas, Delarbre, Laure, Le-Borgne, Hélène, Parent, Annick, Didier, Patrick, Marquette, Jean-Pierre, Lowinski, Maryse, Houtmann, Jacques, Lamberton, Annabelle, Debussche, Laurent, Alexey, Rak
Publikováno v:
Small GTPases; Jan2022, Vol. 13 Issue 1, p225-238, 14p
Publikováno v:
ChemMedChem; 6/5/2019, Vol. 14 Issue 11, p1115-1127, 13p
Autor:
Linke, Pawel, Amaning, Kwame, Maschberger, Melanie, Vallee, Francois, Steier, Valerie, Baaske, Philipp, Duhr, Stefan, Breitsprecher, Dennis, Rak, Alexey
Publikováno v:
Journal of Biomolecular Screening; Apr2016, Vol. 21 Issue 4, p414-421, 8p
Autor:
Mark Wigglesworth
High Throughput Screening (HTS) is one of several hit identification approaches that are part of a developing and evolving toolbox for the discovery of pharmaceutical start points. HTS remains one of the most successful approaches, and therefore an i
