Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kwai Fung Hui"'
Autor:
Weitao Lin, Yim Ling Yip, Lin Jia, Wen Deng, Hong Zheng, Wei Dai, Josephine Mun Yee Ko, Kwok Wai Lo, Grace Tin Yun Chung, Kevin Y. Yip, Sau-Dan Lee, Johnny Sheung-Him Kwan, Jun Zhang, Tengfei Liu, Jimmy Yu-Wai Chan, Dora Lai-Wan Kwong, Victor Ho-Fun Lee, John Malcolm Nicholls, Pierre Busson, Xuefeng Liu, Alan Kwok Shing Chiang, Kwai Fung Hui, Hin Kwok, Siu Tim Cheung, Yuk Chun Cheung, Chi Keung Chan, Bin Li, Annie Lai-Man Cheung, Pok Man Hau, Yuan Zhou, Chi Man Tsang, Jaap Middeldorp, Honglin Chen, Maria Li Lung, Sai Wah Tsao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The lack of appropriate models restricts pre-clinical research for nasopharyngeal carcinoma (NPC). Here the authors report the development and characterization of NPC patient-derived xenografts (PDXs), and EBV positive NPC cell line from patient tumo
Externí odkaz:
https://doaj.org/article/0bf1deca4e9646d1b93328014cc28ef0
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Epstein-Barr virus (EBV) is strongly associated with a spectrum of EBV-associated lymphoproliferative diseases (EBV-LPDs) ranging from post-transplant lymphoproliferative disorder, B cell lymphomas (e.g., endemic Burkitt lymphoma, Hodgkin lymphoma, a
Externí odkaz:
https://doaj.org/article/4d8fb3fe164d4aea879fd4ce19d6db36
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145994 (2015)
Phorbol esters, which are protein kinase C (PKC) activators, and histone deacetylase (HDAC) inhibitors, which cause enhanced acetylation of cellular proteins, are the main classes of chemical inducers of Epstein-Barr virus (EBV) lytic cycle in latent
Externí odkaz:
https://doaj.org/article/bf5d5cd890534242ae53f89f4650b44b
Publikováno v:
Viruses, Vol 9, Iss 11, p 352 (2017)
Epstein-Barr virus (EBV) is closely associated with several lymphomas (endemic Burkitt lymphoma, Hodgkin lymphoma and nasal NK/T-cell lymphoma) and epithelial cancers (nasopharyngeal carcinoma and gastric carcinoma). To maintain its persistence in th
Externí odkaz:
https://doaj.org/article/2139b588379b405ab8b342a89b556938
PDF File - 24K, Legends for Supplementary Figures 1-4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa51cf90306c896fd7647e2b82886d46
https://doi.org/10.1158/1535-7163.22497630.v1
https://doi.org/10.1158/1535-7163.22497630.v1
PDF File - 487K, Effects of bortezomib/SAHA on EBV-negative and EBV-positive NPC cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30388ca63731b4510c0ed6d29b87833c
https://doi.org/10.1158/1535-7163.22497636.v1
https://doi.org/10.1158/1535-7163.22497636.v1
PDF File - 2531K, Effects of bortezomib/SAHA on expression of tumor suppressor genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344982a215880c3e133bcef18eaba960
https://doi.org/10.1158/1535-7163.22497639
https://doi.org/10.1158/1535-7163.22497639
PDF File - 5453K, Effects of bortezomib/SAHA on tumor growth suppression of HONE1 and HA NPC xenografts in nude mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09460af5babc6ae6e18a47c67c063a1a
https://doi.org/10.1158/1535-7163.22497633
https://doi.org/10.1158/1535-7163.22497633
A novel drug combination of a proteasome inhibitor, bortezomib, and a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), was tested in nasopharyngeal carcinoma (NPC), both in vitro and in vivo. Dose-response of different concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3966dbd932f603efa3932ff5205b921b
https://doi.org/10.1158/1535-7163.c.6535674
https://doi.org/10.1158/1535-7163.c.6535674
Publikováno v:
Cancers, Vol 12, Iss 2142, p 2142 (2020)
Cancers
Cancers
Epstein–Barr virus (EBV) lytic induction therapy is an emerging virus-targeted therapeutic approach that exploits the presence of EBV in tumor cells to confer specific killing effects against EBV-associated malignancies. Efforts have been made in t