Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kwahun Lee"'
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 604 (2022)
The elevated intracellular production of or extracellular exposure to reactive oxygen species (ROS) causes oxidative stress to cells, resulting in deleterious irreversible biomolecular reactions (e.g., lipid peroxidation) and disease progression. The
Externí odkaz:
https://doaj.org/article/08b0adb5f538454eb54e6f39dde0c616
Autor:
Ajmeeta Sangtani, Kwahun Lee, Okhil K. Nag, Kimihiro Susumu, R. Joseph Weiblen, Mijin Kim, Igor Vurgaftman, Sz-Chian Liou, James B. Delehanty, Eunkeu Oh
Publikováno v:
Chemistry of Materials. 35:163-176
Autor:
Divita Mathur, Katherine E. Rogers, Sebastián A. Díaz, Megan E. Muroski, William P. Klein, Okhil K. Nag, Kwahun Lee, Lauren D. Field, James B. Delehanty, Igor L. Medintz
Publikováno v:
Nano Letters. 22:5037-5045
Publikováno v:
J Am Chem Soc
This paper reports how the endosomal pathways of nanoparticle (NP) constructs with different surface curvatures are affected by their order of delivery. Sequential incubation of CpG (cytosine-phosphate-guanine)-conjugated spiky and spherical gold NPs
Publikováno v:
Nano Lett
This Letter describes how the endosomal organization of immunostimulatory nanoconstructs can tune the in vitro activation of macrophages. Nanoconstructs composed of gold nanoparticles conjugated with unmethylated cytosine-phosphate-guanine (CpG) olig
Autor:
Kwahun Lee, Yan Yu
Publikováno v:
Soft Matter. 15:2373-2380
In this study, we report the complex effects of charged lipids on the interaction between amphiphilic Janus nanoparticles and lipid bilayers. Janus nanoparticles are cationic on one hemisphere and hydrophobic on the other. We show that the nanopartic
Autor:
Yan Yu, Kwahun Lee
Publikováno v:
Langmuir. 34:12387-12393
Amphiphilic nanoparticles are known to cause defects in lipid bilayers. However, we have shown recently that their disruptive effects are significantly enhanced when surface charges and hydrophobic groups are spatially segregated on opposite hemisphe
Publikováno v:
ACS Nano. 12:3646-3657
The surface coatings of nanoparticles determine their interaction with biomembranes, but studies have been limited almost exclusively to nanoparticles with a uniform surface chemistry. Although nanoparticles are increasingly made with complex surface
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 355:479-486
Luminescent silver nanodots are bright, silver cluster-based emitters with tunable emission windows from the blue to near-IR. Their stability and photophysical properties depend highly on the protection group that forms coordinate bonds with the clus
Publikováno v:
Chemistry of Materials. 29:1448-1460
Janus particles have two distinct surfaces or compartments. This enables novel applications that are impossible with homogeneous particles, ranging from the engineering of active colloidal metastructures to creating multimodal therapeutic materials.