Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kvetoslava Vrankova"'
Autor:
Gerardo G Mackenzie, Lauren E Bartels, Gang Xie, Ioannis Papayannis, Ninche Alston, Kvetoslava Vrankova, Nengtai Ouyang, Basil Rigas
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 10, Pp 1184-1195 (2013)
Pancreatic cancer has one of the poorest prognoses among all cancers partly because of its persistent resistance to chemotherapy. The currently limited treatment options for pancreatic cancer underscore the need for more efficient agents. Because act
Externí odkaz:
https://doaj.org/article/0612c5737e624398b867588793fe633e
Autor:
Gerardo G Mackenzie, Liqun Huang, Ninche Alston, Nengtai Ouyang, Kvetoslava Vrankova, George Mattheolabakis, Panayiotis P Constantinides, Basil Rigas
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e61532 (2013)
New agents are needed to treat pancreatic cancer, one of the most lethal human malignancies. We synthesized phospho-valproic acid, a novel valproic acid derivative, (P-V; MDC-1112) and evaluated its efficacy in the control of pancreatic cancer. P-V i
Externí odkaz:
https://doaj.org/article/5b8c44d22d1845ad9f8891e3cd659fed
Autor:
Basil Rigas, Levy Kopelovich, Despina Komninou, Yu Sun, Liqun Huang, Kvetoslava Vrankova, Gang Xie, Nengtai Ouyang, Gerardo G. Mackenzie
Supplementary Figure 1 from Phospho-Sulindac (OXT-328) Combined with Difluoromethylornithine Prevents Colon Cancer in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680a2785f6d610c779c04ed79a116f4f
https://doi.org/10.1158/1940-6207.22524617.v1
https://doi.org/10.1158/1940-6207.22524617.v1
Autor:
Basil Rigas, Despina Komninou, Kvetoslava Vrankova, Gang Xie, Nengtai Ouyang, Yu Sun, Gerardo G. Mackenzie, Liqun Huang
Nonsteroidal anti-inflammatory drugs (NSAID) exhibit antineoplastic properties, but conventional NSAIDs do not fully meet safety and efficacy criteria for use as anticancer agents. In this study, we evaluated the chemotherapeutic efficacy of 5 novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8c3c24f47a1375ede14dc2f7a31dcf6
https://doi.org/10.1158/0008-5472.c.6503046.v1
https://doi.org/10.1158/0008-5472.c.6503046.v1
Autor:
Basil Rigas, Despina Komninou, Kvetoslava Vrankova, Gang Xie, Nengtai Ouyang, Yu Sun, Gerardo G. Mackenzie, Liqun Huang
PDF file - 254K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b003ffb2517bf510c039cda326a8f7a0
https://doi.org/10.1158/0008-5472.22390773
https://doi.org/10.1158/0008-5472.22390773
Autor:
Kvetoslava Vrankova, Lauren E Bartels, Gang Xie, Ninche Alston, Gerardo G. Mackenzie, Ioannis Papayannis, Basil Rigas, Nengtai Ouyang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 10, Pp 1184-1195 (2013)
Pancreatic cancer has one of the poorest prognoses among all cancers partly because of its persistent resistance to chemotherapy. The currently limited treatment options for pancreatic cancer underscore the need for more efficient agents. Because act
Autor:
Yu Sun, Nengtai Ouyang, Despina Komninou, Gerardo G. Mackenzie, Gang Xie, Basil Rigas, Kvetoslava Vrankova, Liqun Huang
Publikováno v:
Cancer Research. 71:7617-7627
Nonsteroidal anti-inflammatory drugs (NSAID) exhibit antineoplastic properties, but conventional NSAIDs do not fully meet safety and efficacy criteria for use as anticancer agents. In this study, we evaluated the chemotherapeutic efficacy of 5 novel
Autor:
Despina Komninou, Yu Sun, Levy Kopelovich, Gang Xie, Kvetoslava Vrankova, Liqun Huang, Basil Rigas, Gerardo G. Mackenzie, Nengtai Ouyang
Publikováno v:
Cancer Prevention Research. 4:1052-1060
The nonsteroidal anti-inflammatory drug (NSAID) sulindac and the ornithine decarboxylase (ODC) antagonist difluoromethylornithine (DFMO), individually and together, are effective inhibitors of colon carcinogenesis. However, chronic use of sulindac is
Publikováno v:
Tetrahedron. 65:9481-9486
Asymmetric reduction of prochiral ketimines 1a–f with trichlorosilane can be catalyzed by the Lewis-basic formamides (S)-4a,b, derived from N-methyl valine, with ≤91% enantioselectivity and low catalyst loading (≤5 mol %) at room temperature in
Publikováno v:
The Journal of Organic Chemistry. 74:5839-5849
Enantioselective reduction of ketimines 6-10 with trichlorosilane can be catalyzed by the N-methyl valine-derived Lewis-basic formamide (S)-23 (Sigamide) with high enantioselectivity (or = 97% ee) and low catalyst loading (1-5 mol %) at room temperat