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Seven-membered ring nucleobases as inhibitors of human cytidine deaminase and APOBEC3A.

Autor: Kurup HM; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. e.harjes@massey.ac.nz.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand., Kvach MV; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. e.harjes@massey.ac.nz., Harjes S; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. e.harjes@massey.ac.nz., Jameson GB; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. e.harjes@massey.ac.nz.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand., Harjes E; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. e.harjes@massey.ac.nz.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand., Filichev VV; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. e.harjes@massey.ac.nz.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand.

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2023 Jun 21; Vol. 21 (24), pp. 5117-5128. Date of Electronic Publication: 2023 Jun 21.

Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity.

Autor: Barzak FM; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand., Ryan TM; SAXS/WAXS, Australian Synchrotron/ANSTO, 800 Blackburn Road, Clayton, VIC 3168, Australia., Mohammadzadeh N; Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Harjes S; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand., Kvach MV; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand., Kurup HM; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand., Krause KL; Department of Biochemistry, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.; Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand., Chelico L; Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Filichev VV; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand.; Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand., Harjes E; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand.; Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand., Jameson GB; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand.; Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand.

Publikováno v: Viruses [Viruses] 2022 Sep 06; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 06.

Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA.

Autor: Kvach MV; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand., Barzak FM; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand., Harjes S; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand., Schares HAM; Department of Medicinal Chemistry, University of Minnesota, 2231 6th Street SE, Minneapolis, MN, 55455, USA., Kurup HM; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand., Jones KF; Department of Chemistry, University of Minnesota, 207 Pleasant St SE, Minneapolis, MN, 55455, USA., Sutton L; Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, 21st Ave S, Nashville, TN, 37232, USA., Donahue J; Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, 21st Ave S, Nashville, TN, 37232, USA., D'Aquila RT; Division of Infectious Diseases and, Northwestern HIV Translational Research Center, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2330, Chicago, IL, 60611, USA., Jameson GB; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand., Harki DA; Department of Medicinal Chemistry, University of Minnesota, 2231 6th Street SE, Minneapolis, MN, 55455, USA.; Department of Chemistry, University of Minnesota, 207 Pleasant St SE, Minneapolis, MN, 55455, USA., Krause KL; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Biochemistry, University of Otago, P. O. Box 56, Dunedin, 9054, New Zealand., Harjes E; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand., Filichev VV; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2020 Apr 01; Vol. 21 (7), pp. 1028-1035. Date of Electronic Publication: 2019 Dec 19.

Novel homo Yin-Yang probes improve sensitivity in RT-qPCR detection of low copy HIV RNA.

Autor: Farzan VM; Skolkovo Institute of Science and Technology, Skolkovo, Moscow 121205, Russia., Kvach MV; Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, Surganova 13, Minsk 220072, Belarus., Aparin IO; Skolkovo Institute of Science and Technology, Skolkovo, Moscow 121205, Russia; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia., Kireev DE; Central Research Institute of Epidemiology, Novogireevskaya 3a, Moscow 111123, Russia., Prikazchikova TA; Skolkovo Institute of Science and Technology, Skolkovo, Moscow 121205, Russia., Ustinov AV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia., Shmanai VV; Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, Surganova 13, Minsk 220072, Belarus., Shipulin GA; Central Research Institute of Epidemiology, Novogireevskaya 3a, Moscow 111123, Russia; Federal State Budgetary Institution 'Center for Strategic Planning and Management of Biomedical Health Risks' of the Ministry of Health, Pogodinskaya 10b1, Moscow 119121, Russia., Korshun VA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia; Gause Institute of New Antibiotics, Bolshaya Pirogovskaya 11, Moscow 119021, Russia. Electronic address: korshun@ibch.ru., Zatsepin TS; Skolkovo Institute of Science and Technology, Skolkovo, Moscow 121205, Russia; Department of Chemistry, Lomonosov Moscow State University, Leninskie gory 3, Moscow 119992, Russia. Electronic address: t.zatsepin@skoltech.ru.

Publikováno v: Talanta [Talanta] 2019 Mar 01; Vol. 194, pp. 226-232. Date of Electronic Publication: 2018 Oct 16.