Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Kuznik BI"'
Autor:
Kuznik Bi, V. Kh. Khavinson, A. V. Trofimov, E. Magen, V. A. Volchkov, S A Rukavishnikova, T A Akhmedov, O. N. Titova, V V Potemkin, S. V. Trofimova
Publikováno v:
Stem Cell Reviews and Reports
Graphical Abstract The paper presents the results of a standard and complex treatment method using the peptide drug thymus thymalin in patients with COVID-19. One of the mechanisms of the immunomodulatory effect of thymalin is considered to be the ab
Publikováno v:
Молекулярная биология. 53:339-348
Cortexin is a clinically approved cerebral cortex polypeptide complex in calves. The mechanism of cortexin action is not understood well. Two cortexin derivatives, short peptides EDR and DS with neuroprotective activity, were synthesized. According t
Publikováno v:
Molecules
Molecules, Vol 25, Iss 4389, p 4389 (2020)
Molecules, Vol 25, Iss 4389, p 4389 (2020)
There is a vast practice of using antimalarial drugs, RAS inhibitors, serine protease inhibitors, inhibitors of the RNA-dependent RNA polymerase of the virus and immunosuppressants for the treatment of the severe form of COVID-19, which often occurs
Autor:
A Yu Terekhov, D Yu Kormilets, V. Kh. Khavinson, Kuznik Bi, A T Mar'yanovich, Natalia Linkova
Publikováno v:
Bulletin of experimental biology and medicine. 168(5)
Peptide KE exhibits immunoprotective, geroprotective, and oncostatic activities and stimulates functional activity of fibroblasts. The KE motif is present in amino acid sequences of some cytokines and peptide hormones functionally similar to KE pepti
Publikováno v:
Biology Bulletin Reviews. 6:141-148
GDF11 protein, the growth differentiation factor 11, which belongs to the TGF-β superfamily (transforming growth factor β), shows marked geroprotective effects on the cardiovascular and nervous systems. The cardioprotective and myoprotective effect
Publikováno v:
Advances in Gerontology. 5:133-140
Cytokines CCL11 (eotaxin) and HMGB1 (alarmin 1) are molecular markers of ageing and neurological, cardiovascular, and immune diseases. Created at the St. Petersburg Institute of Bioregulation and Gerontology, these short peptides are known to regulat
Publikováno v:
Bulletin of Experimental Biology and Medicine. 160:347-349
Irisin produced by muscles during exercise and promoting fat burning also exhibits geroprotective effect and induces telomere elongation in normal somatic cells. Special attention is paid to studies of the role of peptides Lys-Glu, Glu-Asp-Arg, and A
Publikováno v:
Advances in Gerontology. 4:346-361
This paper reviews the results of long-term studies by the authors on the clinical efficacy of peptide bioregulators (Timalin, Thymogen, Vilon, Epithalamin, Prostatilen, Cortexin, and Retinalamin) for the prevention of diseases and treatment of peopl
Publikováno v:
Advances in Gerontology. 3:243-254
The review contains different aspects indicating the participation of cytokines in aging-associated diseases. Authors reveal the role of short peptides in molecular mechanisms of homeostatic regulation in immune, cardiovascular, haemostatic systems w
Publikováno v:
Advances in Gerontology. 3:225-235
This review summarizes the results of longterm research of authors who studied the mechanisms of aging and the effectiveness of peptide bioregulators in preventing agerelated diseases in laboratory ani� mals. The data on evaluating the peptide effe