Moderate but not severe hypothermia increases intracellular cyclic AMP through preserved production and reduced elimination.

Autor: Kuzmiszyn AK; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT - the Arctic University of Norway, Tromsø, Norway; Norwegian Air Ambulance Foundation, Research and Development Department, Oslo, Norway; Division of Surgical Medicine and Intensive Care, University Hospital of North Norway, Tromsø, Norway., Selli AL; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT - the Arctic University of Norway, Tromsø, Norway., Furuholmen M; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT - the Arctic University of Norway, Tromsø, Norway., Smaglyukova N; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT - the Arctic University of Norway, Tromsø, Norway., Kondratiev T; Anesthesia and Critical Care Research Group, Department of Clinical Medicine, UiT - the Arctic University of Norway, Tromsø, Norway., Fuskevåg OM; Department of Laboratory Medicine, Division of Diagnostic Services, University Hospital of North Norway, Tromsø, Norway., Sager G; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT - the Arctic University of Norway, Tromsø, Norway., Dietrichs ES; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT - the Arctic University of Norway, Tromsø, Norway; Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway. Electronic address: erik.sveberg.dietrichs@uit.no.

Publikováno v: Cryobiology [Cryobiology] 2023 Mar; Vol. 110, pp. 18-23. Date of Electronic Publication: 2023 Jan 14.

Treatment of Cardiovascular Dysfunction with PDE3-Inhibitors in Moderate and Severe Hypothermia-Effects on Cellular Elimination of Cyclic Adenosine Monophosphate and Cyclic Guanosine Monophosphate.

Autor: Kuzmiszyn AK; Norwegian Air Ambulance Foundation, Research and Development Department, Oslo, Norway.; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway.; Division of Surgical Medicine and Intensive Care, University Hospital of North Norway, Tromsø, Norway., Selli AL; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway., Smaglyukova N; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway., Kondratiev T; Anesthesia and Critical Care Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway., Fuskevåg OM; Department of Laboratory Medicine, Division of Diagnostic Services, University Hospital of North Norway, Tromsø, Norway., Lyså RA; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway., Ravna AW; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway., Tveita T; Division of Surgical Medicine and Intensive Care, University Hospital of North Norway, Tromsø, Norway.; Anesthesia and Critical Care Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway., Sager G; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway., Dietrichs ES; Experimental and Clinical Pharmacology, Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway.; Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.

Publikováno v: Frontiers in physiology [Front Physiol] 2022 Jul 13; Vol. 13, pp. 923091. Date of Electronic Publication: 2022 Jul 13 (Print Publication: 2022).