ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome.

Autor: Liiv M; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Vaarmann A; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia. annika.vaarmann@ut.ee., Safiulina D; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Choubey V; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Gupta R; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Kuum M; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Janickova L; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.; Chair of Pharmacology, Faculty of Science and Medicine, University of Fribourg, Ch. du Musée 14, 1700, Fribourg, Switzerland.; Department of Cell Pharmacology and Developmental Toxicology, Institute of Experimental Pharmacology and Toxicology, Dúbravská cesta 9, 84104, Bratislava, Slovakia., Hodurova Z; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.; Department of Cell Pharmacology and Developmental Toxicology, Institute of Experimental Pharmacology and Toxicology, Dúbravská cesta 9, 84104, Bratislava, Slovakia., Cagalinec M; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.; Department of Cellular Cardiology, Institute of Experimental Endocrinology, Biomedical Research Center and Centre of Excellence for Advanced Materials Application, Slovak Academy of Sciences, Dúbravská cesta 9, 84505, Bratislava, Slovakia., Zeb A; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Hickey MA; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Huang YL; Department of Life Sciences, Institute of Genome Sciences and Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, 155 Li-Nong St., Section 2, Peitou, Taipei, 11221, Taiwan., Gogichaishvili N; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Mandel M; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Plaas M; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Vasar E; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia., Loncke J; Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, KU Leuven, O&N1 Herestraat 49, Leuven, Belgium., Vervliet T; Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, KU Leuven, O&N1 Herestraat 49, Leuven, Belgium., Tsai TF; Department of Life Sciences, Institute of Genome Sciences and Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, 155 Li-Nong St., Section 2, Peitou, Taipei, 11221, Taiwan., Bultynck G; Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, KU Leuven, O&N1 Herestraat 49, Leuven, Belgium., Veksler V; Laboratory of Signaling and Cardiovascular Pathophysiology, Université Paris-Saclay, Inserm, UMR-S 1180, 91400, Orsay, France., Kaasik A; Departments of Pharmacology and Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia. allen.kaasik@ut.ee.

Publikováno v: Nature communications [Nat Commun] 2024 Jul 21; Vol. 15 (1), pp. 6143. Date of Electronic Publication: 2024 Jul 21.

Comparison of the Mitophagy and Apoptosis Related Gene Expressions in Waste Embryo Culture Medium of Female Infertility Types.

Autor: Kütük, Duygu^1,2 (AUTHOR) duygukutukk@gmail.com, Öner, Çağrı³ (AUTHOR) cagrioner@klu.edu.tr, Başar, Murat⁴ (AUTHOR), Akcay, Berkay² (AUTHOR), Olcay, İbrahim Orçun² (AUTHOR), Çolak, Ertuğrul⁵ (AUTHOR), Selam, Belgin⁶ (AUTHOR) duygukutukk@gmail.com, Cincik, Mehmet¹ (AUTHOR)

Publikováno v: Life (2075-1729). Nov2024, Vol. 14 Issue 11, p1507. 13p.

A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome.

Autor: Ahuja, K.^1,2,3 (AUTHOR), Vandenabeele, M.^1,2 (AUTHOR), Nami, F.³ (AUTHOR), Lefevere, E.¹ (AUTHOR), Van hoecke, J.¹ (AUTHOR), Bergmans, S.² (AUTHOR), Claes, M.¹ (AUTHOR), Vervliet, T.⁴ (AUTHOR), Neyrinck, K.³ (AUTHOR), Burg, T.^5,6 (AUTHOR), De Herdt, D.¹ (AUTHOR), Bhaskar, P.³ (AUTHOR), Zhu, Y.³ (AUTHOR), Looser, Z. J.⁷ (AUTHOR), Loncke, J.⁴ (AUTHOR), Gsell, W.⁸ (AUTHOR), Plaas, M.⁹ (AUTHOR), Agostinis, P.¹⁰ (AUTHOR), Swinnen, J. V.¹¹ (AUTHOR), Van Den Bosch, L.^5,6 (AUTHOR)

Publikováno v: Acta Neuropathologica Communications. 8/28/2024, Vol. 12 Issue 1, p1-23. 23p.

Mitochondrial transport proteins RHOT1 and RHOT2 serve as docking sites for PRKN-mediated mitophagy.

Autor: Safiulina D; a Department of Pharmacology , University Tartu , Tartu , Estonia., Kuum M; a Department of Pharmacology , University Tartu , Tartu , Estonia., Choubey V; a Department of Pharmacology , University Tartu , Tartu , Estonia., Hickey MA; a Department of Pharmacology , University Tartu , Tartu , Estonia., Kaasik A; a Department of Pharmacology , University Tartu , Tartu , Estonia.

Publikováno v: Autophagy [Autophagy] 2019 May; Vol. 15 (5), pp. 930-931. Date of Electronic Publication: 2019 Mar 04.

P.1.c.009 - Mitochondrial biogenesis is a rate limiting-factor for axonal growth

Autor: Mandel, M., Vaarmann, A., Zeb, A., Wareski, P., Kuum, M., Liiv, M., Choubey, V., Antsov, E.

Publikováno v: In European Neuropsychopharmacology October 2016 26 Supplement 2:S191-S192