Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kuu Ikäheimo"'
Autor:
Kuu, Ikäheimo, Anni, Herranen, Vilma, Iivanainen, Tuuli, Lankinen, Antti A, Aarnisalo, Ville, Sivonen, Kashyap A, Patel, Korcan, Demir, Mart, Saarma, Maria, Lindahl, Ulla, Pirvola
Publikováno v:
Life Science Alliance
The authors show in the mouse how the auditory hair cell structural maintenance is perturbed by the inactivation of Manf and the concomitant ER stress, causing early-onset, progressive hearing loss.
Failure in the structural maintenance of the h
Failure in the structural maintenance of the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a0df97a54dd8d8ac38229f10cc9791f
https://pubmed.ncbi.nlm.nih.gov/34815294
https://pubmed.ncbi.nlm.nih.gov/34815294
Autor:
Mart Saarma, Kuu Ikäheimo, Anni Herranen, Tuuli Lankinen, Bernd Fritzsch, Emmi Pakarinen, Ulla Pirvola, Maria Lindahl
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 2, Pp 1-12 (2020)
Cell Death and Disease, Vol 11, Iss 2, Pp 1-12 (2020)
The non-conventional neurotrophic factor mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-resident protein that promotes ER homeostasis. MANF has a cytoprotective function, shown in the central nervous syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1518ef830c09a892ebf580318e90c6
https://doi.org/10.1038/s41419-020-2286-6
https://doi.org/10.1038/s41419-020-2286-6
Publikováno v:
Journal of the Association for Research in Otolaryngology. 19:637-652
Various stressors, such as loud sounds and the effects of aging, impair the function and viability of the cochlear sensory cells, the hair cells. Stressors trigger pathophysiological changes in the cochlear non-sensory cells as well. We have here stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2c0d14591318b800fc336d171ec600
https://doi.org/10.1007/s10162-018-00691-2
https://doi.org/10.1007/s10162-018-00691-2