Non-haematopoietic Sca-1 ⁺ Cells in the Retina of Adult Mice Express Functional TLR2.

Autor: Flores A; Departamento de Microbiología y Ecología, Universitat de València, Valencia, Spain., Fernández-Sánchez L; Departamento de Óptica, Farmacología y Anatomía, Universidad de Alicante, Alicante, Spain., Kutsyr O; Departamento de Óptica, Farmacología y Anatomía, Universidad de Alicante, Alicante, Spain., Lax P; Departamento de Fisiología, Genética y Microbiología, Universidad de Alicante, Alicante, Spain., Yáñez A; Departamento de Microbiología y Ecología, Universitat de València, Valencia, Spain., Gil ML; Departamento de Microbiología y Ecología, Universitat de València, Valencia, Spain., Gozalbo D; Departamento de Microbiología y Ecología, Universitat de València, Valencia, Spain., Maneu V; Departamento de Óptica, Farmacología y Anatomía, Universidad de Alicante, Alicante, Spain. vmaneu@ua.es.

Publikováno v: Stem cell reviews and reports [Stem Cell Rev Rep] 2024 Apr; Vol. 20 (3), pp. 845-851. Date of Electronic Publication: 2024 Jan 06.

Expression of two major isoforms of MYO7A in the retina: Considerations for gene therapy of Usher syndrome type 1B.

Autor: Gilmore WB; Department of Ophthalmology and Stein Eye Institute, Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Hultgren NW; Department of Ophthalmology and Stein Eye Institute, Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Chadha A; Department of Ophthalmology and Stein Eye Institute, Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Barocio SB; Department of Ophthalmology and Stein Eye Institute, Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Zhang J; Department of Ophthalmology and Stein Eye Institute, Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Kutsyr O; CellSight Ocular Stem Cell and Regeneration Research Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA., Flores-Bellver M; CellSight Ocular Stem Cell and Regeneration Research Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA., Canto-Soler MV; CellSight Ocular Stem Cell and Regeneration Research Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA., Williams DS; Department of Ophthalmology and Stein Eye Institute, Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: dswilliams@ucla.edu.

Publikováno v: Vision research [Vision Res] 2023 Nov; Vol. 212, pp. 108311. Date of Electronic Publication: 2023 Aug 15.

A Slc38a8 Mouse Model of FHONDA Syndrome Faithfully Recapitulates the Visual Deficits of Albinism Without Pigmentation Defects.

Autor: Guardia A; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER-ISCIII), Madrid, Spain., Fernández A; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER-ISCIII), Madrid, Spain., Seruggia D; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER-ISCIII), Madrid, Spain., Chotard V; Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France., Sánchez-Castillo C; Department of Physiology, Genetics and Microbiology, University of Alicante, Alicante, Spain., Kutsyr O; Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain., Sánchez-Sáez X; Department of Physiology, Genetics and Microbiology, University of Alicante, Alicante, Spain., Zurita E; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER-ISCIII), Madrid, Spain., Cantero M; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER-ISCIII), Madrid, Spain., Rebsam A; Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France., Cuenca N; Department of Physiology, Genetics and Microbiology, University of Alicante, Alicante, Spain., Montoliu L; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER-ISCIII), Madrid, Spain.

Publikováno v: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2023 Oct 03; Vol. 64 (13), pp. 32.

Inherited Retinal Dystrophies: Role of Oxidative Stress and Inflammation in Their Physiopathology and Therapeutic Implications

Autor: Pinilla I, Maneu V, Campello L, Fernández-Sánchez L, Martínez-Gil N, Kutsyr O, Sánchez-Sáez X, Sánchez-Castillo C, Lax P, Cuenca N

Publikováno v: Antioxidants
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname

Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically heterogeneous diseases characterized by the progressive degeneration of the retina, ultimately leading to loss of visual function. Oxidative stress and inflammation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::51f62d9f281cc7bec95241bab0eac3cd
https://pubmed.ncbi.nlm.nih.gov/35739983/

Retinitis pigmentosa is associated with shifts in the gut microbiome

Autor: Kutsyr O, Maestre-Carballa L, Lluesma-Gomez M, Martinez-Garcia M, Cuenca N, Lax P

Publikováno v: SCIENTIFIC REPORTS
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname

The gut microbiome is known to influence the pathogenesis and progression of neurodegenerative diseases. However, there has been relatively little focus upon the implications of the gut microbiome in retinal diseases such as retinitis pigmentosa (RP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::b5e856acf359ac448b33b8f1e6c3e51f
https://fundanet.isabial.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=8295