Genome-wide off-target analyses of CRISPR/Cas9-mediated T-cell receptor engineering in primary human T cells.

Autor: Kaeuferle T; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital University Hospital, LMU Munich Munich Germany.; German Center for Infection Research (DZIF) Munich Germany., Stief TA; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital University Hospital, LMU Munich Munich Germany.; German Center for Infection Research (DZIF) Munich Germany., Canzar S; Gene Center Ludwig Maximilians University of Munich Munich Germany., Kutlu NN; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital University Hospital, LMU Munich Munich Germany., Willier S; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital University Hospital, LMU Munich Munich Germany., Stenger D; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital University Hospital, LMU Munich Munich Germany., Ferrada-Ernst P; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital University Hospital, LMU Munich Munich Germany., Habjan N; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital University Hospital, LMU Munich Munich Germany., Peters AE; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital University Hospital, LMU Munich Munich Germany., Busch DH; German Center for Infection Research (DZIF) Munich Germany.; Institute for Medical Microbiology, Immunology and Hygiene Technische Universität München (TUM) Munich Germany., Feuchtinger T; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation Dr. von Hauner Children's Hospital University Hospital, LMU Munich Munich Germany.; German Center for Infection Research (DZIF) Munich Germany.

Publikováno v: Clinical & translational immunology [Clin Transl Immunology] 2022 Jan 23; Vol. 11 (1), pp. e1372. Date of Electronic Publication: 2022 Jan 23 (Print Publication: 2022).