Cellular senescence and metabolic reprogramming model based on bulk/single-cell RNA sequencing reveals PTGER4 as a therapeutic target for ccRCC.

Autor: Zhou, Lijie^1,2 (AUTHOR) zhouxiaozhou29@126.com, Zeng, Youmiao^1,3 (AUTHOR), Liu, Yuanhao^1,2 (AUTHOR), Du, Kaixuan^1,2 (AUTHOR), Luo, Yongbo^1,2 (AUTHOR), Dai, Yiheng^1,3 (AUTHOR), Pan, Wenbang^1,2 (AUTHOR), Zhang, Lailai^1,2 (AUTHOR), Zhang, Lei⁴ (AUTHOR) zhanglei_address@163.com, Tian, Fengyan⁵ (AUTHOR) fccguzh@zzu.edu.cn, Gu, Chaohui^1,2 (AUTHOR) zgwhgch@hotmail.com

Publikováno v: BMC Cancer. 4/11/2024, Vol. 24 Issue 1, p1-23. 23p.

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Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation.

Autor: Zhang Q; College of Life Science, Northeast Forestry University, Harbin, China Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA Present address: Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, MI 48109, USA., Wan M; Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Shi J; College of Life Science, Northeast Forestry University, Harbin, China., Horita DA; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Miller LD; Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Kute TE; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Kridel SJ; Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Kulik G; Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA Life Sciences Program, College of Science & General Studies, Alfaisal University, Riyadh 11533, Saudi Arabia., Sui G; College of Life Science, Northeast Forestry University, Harbin, China Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA gcsui@nefu.edu.cn gsui@wakehealth.edu.

Publikováno v: Journal of molecular cell biology [J Mol Cell Biol] 2016 Jun; Vol. 8 (3), pp. 232-43. Date of Electronic Publication: 2016 Jan 13.