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pro vyhledávání: '"Kutchukian PS"'
Akademický článek
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Autor:
Thomas JR; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Shelton C 4th; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Murphy J; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Brittain S; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Bray MA; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Aspesi P; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Concannon J; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., King FJ; Novartis Biomedical Research, San Diego, California 92121, United States., Ihry RJ; Novartis Biomedical Research, San Diego, California 92121, United States., Ho DJ; Novartis Biomedical Research, San Diego, California 92121, United States., Henault M; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Hadjikyriacou A; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Neri M; Novartis Biomedical Research, Basel 4056, Switzerland., Sigoillot FD; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Pham HT; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Shum M; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Barys L; Novartis Biomedical Research, Basel 4056, Switzerland., Jones MD; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Martin EJ; Novartis Biomedical Research, Emeryville, California 94608, United States., Blechschmidt A; Novartis Biomedical Research, Basel 4056, Switzerland., Rieffel S; Novartis Biomedical Research, Basel 4056, Switzerland., Troxler TJ; Novartis Biomedical Research, Basel 4056, Switzerland., Mapa FA; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Jenkins JL; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Jain RK; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Kutchukian PS; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Schirle M; Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Renner S; Novartis Biomedical Research, Basel 4056, Switzerland.
Publikováno v:
ACS chemical biology [ACS Chem Biol] 2024 Apr 19; Vol. 19 (4), pp. 938-952. Date of Electronic Publication: 2024 Apr 02.
Autor:
Shen L; Novartis Biomedical Research, Cambridge, MA, 02139, USA. lingling.shen@novartis.com., Fang J; Novartis Biomedical Research, Cambridge, MA, 02139, USA., Liu L; Novartis Biomedical Research, Cambridge, MA, 02139, USA., Yang F; Novartis Biomedical Research, Cambridge, MA, 02139, USA., Jenkins JL; Novartis Biomedical Research, Cambridge, MA, 02139, USA., Kutchukian PS; Novartis Biomedical Research, Cambridge, MA, 02139, USA., Wang H; Novartis Biomedical Research, Cambridge, MA, 02139, USA. he.wang@novartis.com.
Publikováno v:
Journal of cheminformatics [J Cheminform] 2024 Mar 21; Vol. 16 (1), pp. 33. Date of Electronic Publication: 2024 Mar 21.
Autor:
Bukhtiyarova M; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Cook EM; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Hancock PJ; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Hruza AW; MRL, Merck & Co., Inc., Kenilworth, New Jersey, 07033, United States., Shaw AW; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Adam GC; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Barnard RJO; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., McKenna PM; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Holloway MK; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Bell IM; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Carroll S; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Cornella-Taracido I; MRL, Merck & Co., Inc., Boston, Massachusetts, 02115, United States., Cox CD; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Kutchukian PS; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Powell DA; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Strickland C; MRL, Merck & Co., Inc., Kenilworth, New Jersey, 07033, United States., Trotter BW; MRL, Merck & Co., Inc., Boston, Massachusetts, 02115, United States., Tudor M; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Wolkenberg S; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Li J; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States., Tellers DM; MRL, Merck & Co., Inc., West Point, Pennsylvania 19486, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 Dec 23; Vol. 12 (1), pp. 99-106. Date of Electronic Publication: 2020 Dec 23 (Print Publication: 2021).
Autor:
Zhang J; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Muise ES; Department of Genetics and Pharmacogenomics, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Han S; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Kutchukian PS; Department of Chemistry, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Costet P; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Zhu Y; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Kan Y; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Zhou H; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Shah V; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Huang Y; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Saigal A; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Akiyama TE; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Shen XL; Department of Safety Assessment and Laboratory Animal Resources, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Cai TQ; Department of Pharmacology, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Shah K; Department of Pharmacology, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Carballo-Jane E; Department of Pharmacology, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Zycband E; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Yi L; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Tian Y; Department of PPDM, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Chen Y; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Imbriglio J; Department of Chemistry, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Smith E; Department of Pharmacology, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Devito K; Department of Pharmacology, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Conway J; Department of Genetics and Pharmacogenomics, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Ma LJ; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Hoek M; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Sebhat IK; Department of Chemistry, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Peier AM; Department of Pharmacology, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Talukdar S; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., McLaren DG; Department of Chemistry, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Previs SF; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Jensen KK; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Pinto S; Department of Cardiometabolic Diseases, MRL, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA.; Kallyope Inc., 430 E 29 Street, New York, NY 10016, USA.
Publikováno v:
Cell reports. Medicine [Cell Rep Med] 2020 Jul 21; Vol. 1 (4), pp. 100056. Date of Electronic Publication: 2020 Jul 21 (Print Publication: 2020).
Autor:
Kutchukian PS; Modeling and Informatics, Merck & Co., Inc., Boston, MA, USA. Electronic address: peter.kutchukian@merck.com., Chang C; Scientific Modeling Platforms, Merck & Co., Inc., Boston, MA, USA., Fox SJ; QuickBase, Inc., Cambridge, MA, USA., Cook E; Lead Discovery and Optimization, Bristol-Myers Squibb, Pennington, NJ, USA., Barnard R; Infectious Disease, Merck & Co., Inc., West Point, PA, USA., Tellers D; Discovery Chemistry, Merck & Co., Inc., West Point, PA, USA., Wang H; Modeling and Informatics, Merck & Co., Inc., Kenilworth, NJ, USA., Pertusi D; Modeling and Informatics, Merck & Co., Inc., West Point, PA, USA., Glick M; Modeling and Informatics, Merck & Co., Inc., Boston, MA, USA., Sheridan RP; Modeling and Informatics, Merck & Co., Rahway, NJ, USA., Wallace IM; Scientific Information Management, Merck & Co., Inc., Boston, MA, USA., Wassermann AM; Modeling and Informatics, Merck & Co., Inc., Boston, MA, USA. Electronic address: anne.wassermann@merck.com.
Publikováno v:
Drug discovery today [Drug Discov Today] 2018 Jan; Vol. 23 (1), pp. 151-160. Date of Electronic Publication: 2017 Sep 14.
Autor:
Santa Maria JP Jr; Modeling & Informatics, Merck Research Laboratories , Boston, Massachusetts, United States., Park Y; National Institute of Allergy and Infectious Diseases , Bethesda, Maryland, United States., Yang L; Department of Chemistry, Merck Sharp & Dohme Corp. , Kenilworth, New Jersey, United States., Murgolo N; Department of Information & Analytics, Merck Sharp & Dohme Corp. , Kenilworth, New Jersey, United States., Altman MD; Modeling & Informatics, Merck Research Laboratories , Boston, Massachusetts, United States., Zuck P; Research Science, Merck Sharp & Dohme Corp. , North Wales, Pennsylvania, United States., Adam G; Department of Pharmacology, Merck Sharp & Dohme Corp. , North Wales, Pennsylvania, United States., Chamberlin C; Department of Pharmacology, Merck Sharp & Dohme Corp. , Boston, Massachusetts, United States., Saradjian P; Department of Pharmacology, Merck Sharp & Dohme Corp. , Boston, Massachusetts, United States., Dandliker P; Department of Pharmacology, Merck Sharp & Dohme Corp. , Boston, Massachusetts, United States., Boshoff HIM; National Institute of Allergy and Infectious Diseases , Bethesda, Maryland, United States., Barry CE 3rd; National Institute of Allergy and Infectious Diseases , Bethesda, Maryland, United States., Garlisi C; Department of Pharmacology, Merck Sharp & Dohme Corp. , Kenilworth, New Jersey, United States., Olsen DB; Neglected Tropical Disease Discovery, Merck Sharp & Dohme Corp. , West Point, Pennsylvania, United States., Young K; Neglected Tropical Disease Discovery, Merck Sharp & Dohme Corp. , West Point, Pennsylvania, United States., Glick M; Modeling & Informatics, Merck Research Laboratories , Boston, Massachusetts, United States., Nickbarg E; Department of Pharmacology, Merck Sharp & Dohme Corp. , Boston, Massachusetts, United States., Kutchukian PS; Modeling & Informatics, Merck Research Laboratories , Boston, Massachusetts, United States.
Publikováno v:
ACS chemical biology [ACS Chem Biol] 2017 Sep 15; Vol. 12 (9), pp. 2448-2456. Date of Electronic Publication: 2017 Aug 29.
Autor:
Pertusi DA; 1 Modeling and Informatics, Merck & Co., Inc., West Point, PA, USA., O'Donnell G; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Homsher MF; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Solly K; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Patel A; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Stahler SL; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Riley D; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Finley MF; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 4 Discovery Sciences, Janssen Research and Development LLC, Spring House, PA, USA., Finger EN; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 5 Discovery & Preclinical Development, GlaxoSmithKline, Collegeville, PA, USA., Adam GC; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 3 Merck & Co., Inc., West Point, PA, USA., Meng J; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA., Bell DJ; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 6 Merck & Co., Inc., North Wales, PA, USA., Zuck PD; 6 Merck & Co., Inc., North Wales, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Hudak EM; 8 Discovery Sample Management, Merck & Co., Inc., North Wales, PA, USA., Weber MJ; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Nothstein JE; 3 Merck & Co., Inc., West Point, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Locco L; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Quinn C; 4 Discovery Sciences, Janssen Research and Development LLC, Spring House, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Amoss A; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Squadroni B; 3 Merck & Co., Inc., West Point, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Hartnett M; 4 Discovery Sciences, Janssen Research and Development LLC, Spring House, PA, USA.; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Heo MR; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 6 Merck & Co., Inc., North Wales, PA, USA., White T; 8 Discovery Sample Management, Merck & Co., Inc., North Wales, PA, USA., May SA; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Boots E; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA., Roberts K; 7 Automation and Engineering, Merck & Co., Inc., North Wales, PA, USA., Cocchiarella P; 8 Discovery Sample Management, Merck & Co., Inc., North Wales, PA, USA., Wolicki A; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA., Kreamer A; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 9 Merck & Co., Inc., Kenilworth, NJ, USA., Kutchukian PS; 10 Modeling and Informatics, Merck & Co., Inc., Boston, MA, USA., Wassermann AM; 10 Modeling and Informatics, Merck & Co., Inc., Boston, MA, USA., Uebele VN; 2 Screening and Protein Sciences, Merck & Co., Inc., North Wales, PA, USA.; 6 Merck & Co., Inc., North Wales, PA, USA., Glick M; 10 Modeling and Informatics, Merck & Co., Inc., Boston, MA, USA., Rusinko A 3rd; 1 Modeling and Informatics, Merck & Co., Inc., West Point, PA, USA., Culberson JC; 1 Modeling and Informatics, Merck & Co., Inc., West Point, PA, USA.
Publikováno v:
SLAS discovery : advancing life sciences R & D [SLAS Discov] 2017 Sep; Vol. 22 (8), pp. 995-1006. Date of Electronic Publication: 2017 Apr 20.
Autor:
Kutchukian PS; Modeling and Informatics, Merck & Co., Inc., MRL , Boston, Massachusetts, United States., Warren L; Neuroscience, Merck & Co., Inc., MRL , West Point, Pennsylvania, United States., Magliaro BC; Pharmacology, Merck & Co., Inc., MRL , West Point, Pennsylvania, United States., Amoss A; Screening and Protein Sciences, Merck & Co., Inc., MRL , North Wales, Pennsylvania, United States., Cassaday JA; Screening and Protein Sciences, Merck & Co., Inc., MRL , North Wales, Pennsylvania, United States., O'Donnell G; Screening and Protein Sciences, Merck & Co., Inc., MRL , North Wales, Pennsylvania, United States., Squadroni B; Screening and Protein Sciences, Merck & Co., Inc., MRL , North Wales, Pennsylvania, United States., Zuck P; Screening and Protein Sciences, Merck & Co., Inc., MRL , North Wales, Pennsylvania, United States., Pascarella D; Pharmacology, Merck & Co., Inc., MRL , West Point, Pennsylvania, United States., Culberson JC; Modeling and Informatics, Merck & Co., Inc., MRL , West Point, Pennsylvania, United States., Cooke AJ; Chemistry, Merck & Co., Inc., MRL , West Point, Pennsylvania, United States., Hurzy D; Chemistry, Merck & Co., Inc., MRL , West Point, Pennsylvania, United States., Schlegel KS; Chemistry, Merck & Co., Inc., MRL , West Point, Pennsylvania, United States., Thomson F; Neuroscience, Merck & Co., Inc., MRL , West Point, Pennsylvania, United States., Johnson EN; Screening and Protein Sciences, Merck & Co., Inc., MRL , North Wales, Pennsylvania, United States., Uebele VN; Screening and Protein Sciences, Merck & Co., Inc., MRL , North Wales, Pennsylvania, United States., Hermes JD; Screening and Protein Sciences, Merck & Co., Inc., MRL , North Wales, Pennsylvania, United States., Parmentier-Batteur S; Neuroscience, Merck & Co., Inc., MRL , West Point, Pennsylvania, United States., Finley M; Screening and Protein Sciences, Merck & Co., Inc., MRL , North Wales, Pennsylvania, United States.
Publikováno v:
ACS chemical biology [ACS Chem Biol] 2017 Feb 17; Vol. 12 (2), pp. 519-527. Date of Electronic Publication: 2017 Jan 06.
Representing high throughput expression profiles via perturbation barcodes reveals compound targets.
Autor:
Filzen TM; Medical Writing, Merck Research Laboratories, Upper Gwynedd, Pennsylvania, United States of America., Kutchukian PS; Informatics, Merck Research Laboratories, Boston, Massachusetts, United States of America., Hermes JD; Screening & Protein Sciences, Merck Research Laboratories, North Wales, Pennsylvania, United States of America., Li J; Screening and Compound Profiling, Merck Research Laboratories, Kenilworth, New Jersey, United States of America., Tudor M; Informatics, Merck Research Laboratories, West Point, Pennsylvania, United States of America.
Publikováno v:
PLoS computational biology [PLoS Comput Biol] 2017 Feb 09; Vol. 13 (2), pp. e1005335. Date of Electronic Publication: 2017 Feb 09 (Print Publication: 2017).