Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer.

Autor: Saunus JM; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia. j.saunus@uq.edu.au.; Mater Research Institute-The University of Queensland, Translational Research Institute, Woolloongabba, QLD, Australia. j.saunus@uq.edu.au., De Luca XM; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Northwood K; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Raghavendra A; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Hasson A; School of Mathematical Sciences, Queensland University of Technology, Brisbane, QLD, Australia., McCart Reed AE; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Lim M; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Lal S; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Vargas AC; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Kutasovic JR; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Dalley AJ; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Miranda M; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Kalaw E; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Kalita-de Croft P; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Gresshoff I; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Al-Ejeh F; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Gee JMW; Breast Cancer Molecular Pharmacology Unit, School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK., Ormandy C; The Kinghorn Cancer Centre, Garvan Institute of Medical Research and St. Vincent's Hospital Clinical School, UNSW Sydney, Darlinghurst, NSW, Australia., Khanna KK; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Beesley J; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Chenevix-Trench G; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Green AR; Nottingham Breast Cancer Research Centre, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham, UK., Rakha EA; Nottingham Breast Cancer Research Centre, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham, UK., Ellis IO; Nottingham Breast Cancer Research Centre, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham, UK., Nicolau DV Jr; School of Mathematical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.; Mathematical Institute, University of Oxford, and Molecular Sense Ltd, Oxford, UK., Simpson PT; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia., Lakhani SR; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, QLD, Australia. s.lakhani@uq.edu.au.; Pathology Queensland, Royal Brisbane Women's Hospital, Herston, QLD, Australia. s.lakhani@uq.edu.au.

Publikováno v: NPJ breast cancer [NPJ Breast Cancer] 2022 May 02; Vol. 8 (1), pp. 57. Date of Electronic Publication: 2022 May 02.

Correction: McCart Reed et al. The Genomic Landscape of Lobular Breast Cancer. Cancers 2021, 13 , 1950.

Autor: McCart Reed AE; Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD 4029, Australia., Foong S; Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD 4029, Australia.; Pathology Queensland, Royal Brisbane and Women's Hospital, Herston, Brisbane, QLD 4029, Australia., Kutasovic JR; Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD 4029, Australia.; QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD 4006, Australia., Nones K; QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD 4006, Australia., Waddell N; QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD 4006, Australia., Lakhani SR; Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD 4029, Australia.; Pathology Queensland, Royal Brisbane and Women's Hospital, Herston, Brisbane, QLD 4029, Australia., Simpson PT; Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD 4029, Australia.

Publikováno v: Cancers [Cancers (Basel)] 2021 Aug 09; Vol. 13 (16). Date of Electronic Publication: 2021 Aug 09.

Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer-insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system.

Autor: Wafai R; Invasion and Metastasis Unit, St. Vincent's Institute, Melbourne, VIC, Australia.; Department of Surgery, The University of Melbourne, St. Vincent's Hospital, Melbourne, VIC, Australia., Williams ED; Invasion and Metastasis Unit, St. Vincent's Institute, Melbourne, VIC, Australia.; Department of Surgery, The University of Melbourne, St. Vincent's Hospital, Melbourne, VIC, Australia.; Queensland University of Technology, Institute of Health and Biomedical Innovation and School of Biomedical Sciences, Brisbane, QLD, Australia.; Translational Research Institute, Brisbane, QLD, Australia.; Australian Prostate Cancer Research Centre-Queensland and Queensland Bladder Cancer Initiative, Brisbane, QLD, Australia., de Souza E; Department of Surgery, The University of Melbourne, St. Vincent's Hospital, Melbourne, VIC, Australia.; The Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK., Simpson PT; Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia., McCart Reed AE; Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia., Kutasovic JR; Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia., Waltham M; Invasion and Metastasis Unit, St. Vincent's Institute, Melbourne, VIC, Australia.; Department of Surgery, The University of Melbourne, St. Vincent's Hospital, Melbourne, VIC, Australia.; Monash University, Melbourne, VIC, Australia., Snell CE; Cancer Pathology Research Group, Mater Research Institute - The University of Queensland, Brisbane, QLD, Australia.; Mater Pathology, Mater Hospital Brisbane, South Brisbane, QLD, Australia., Blick T; Invasion and Metastasis Unit, St. Vincent's Institute, Melbourne, VIC, Australia.; Queensland University of Technology, Institute of Health and Biomedical Innovation and School of Biomedical Sciences, Brisbane, QLD, Australia., Thompson EW; Invasion and Metastasis Unit, St. Vincent's Institute, Melbourne, VIC, Australia.; Department of Surgery, The University of Melbourne, St. Vincent's Hospital, Melbourne, VIC, Australia.; Queensland University of Technology, Institute of Health and Biomedical Innovation and School of Biomedical Sciences, Brisbane, QLD, Australia.; Translational Research Institute, Brisbane, QLD, Australia., Hugo HJ; Invasion and Metastasis Unit, St. Vincent's Institute, Melbourne, VIC, Australia. honor.hugo@qut.edu.au.; Department of Surgery, The University of Melbourne, St. Vincent's Hospital, Melbourne, VIC, Australia. honor.hugo@qut.edu.au.; Queensland University of Technology, Institute of Health and Biomedical Innovation and School of Biomedical Sciences, Brisbane, QLD, Australia. honor.hugo@qut.edu.au.; Translational Research Institute, Brisbane, QLD, Australia. honor.hugo@qut.edu.au.

Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2020 Dec 04; Vol. 22 (1), pp. 136. Date of Electronic Publication: 2020 Dec 04.

Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1.

Autor: Kalaw E; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia., Lim M; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia.; QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia., Kutasovic JR; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia.; QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia., Sokolova A; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia.; Pathology Queensland, The Royal Brisbane & Women's Hospital, Herston, Brisbane, QLD, Australia., Taege L; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia.; Pathology Queensland, The Royal Brisbane & Women's Hospital, Herston, Brisbane, QLD, Australia., Johnstone K; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia.; Pathology Queensland, The Royal Brisbane & Women's Hospital, Herston, Brisbane, QLD, Australia., Bennett J; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia.; Pathology Queensland, The Royal Brisbane & Women's Hospital, Herston, Brisbane, QLD, Australia., Saunus JM; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia.; QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia., Niland C; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia., Ferguson K; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia., Gresshoff I; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia., Bettington M; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia., Pathmanathan N; Westmead Breast Cancer Institute, University of Sydney, Westmead, NSW, Australia., Tse GM; Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, Hong Kong., Papadimos D; Department of Histopathology, Sullivan Nicolaides Pathology, Bowen Hills, QLD, Australia., Pathmanathan R; Jeffrey Cheah School of Medicine & Health Sciences, Monash University Malaysia, 47500, Bandar Sunway, Selangor, Malaysia., Harris G; Canterbury Health Laboratories, Christchurch, New Zealand/Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Yamaguchi R; Department of Pathology and Laboratory Medicine, Kurume University Medical Center, 155-1 Kokubu, Kurume-shi, 839-0863, Japan., Tan PH; Division of Pathology, Singapore General Hospital, Singapore, Singapore., Fox S; Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC, Australia., O'Toole SA; Garvan Institute of Medical Research and the Kinghorn Cancer Centre, 384 Victoria Street, Darlinghurst, NSW, 2010, Australia.; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia., Simpson PT; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia., Lakhani SR; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia. s.lakhani@uq.edu.au.; Pathology Queensland, The Royal Brisbane & Women's Hospital, Herston, Brisbane, QLD, Australia. s.lakhani@uq.edu.au., McCart Reed AE; Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Herston, Brisbane, QLD, Australia. amy.reed@uq.edu.au.; QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia. amy.reed@uq.edu.au.

Publikováno v: British journal of cancer [Br J Cancer] 2020 Nov; Vol. 123 (11), pp. 1665-1672. Date of Electronic Publication: 2020 Sep 17.

Clinicopathologic significance of nuclear HER4 and phospho-YAP(S ¹²⁷ ) in human breast cancers and matching brain metastases.

Autor: Kalita-de Croft P; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Building 71/98 Royal Brisbane and Women's Hospital, Herston, Qld 4006, Australia., Lim M; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, Qld, Australia., Chittoory H; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, Qld, Australia., de Luca XM; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, Qld, Australia., Kutasovic JR; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, Qld, Australia., Day BW; QIMR Berghofer Medical Research Institute, Herston, Qld, Australia., Al-Ejeh F; QIMR Berghofer Medical Research Institute, Herston, Qld, Australia., Simpson PT; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, Qld, Australia., McCart Reed AE; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, Qld, Australia., Lakhani SR; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, Qld, Australia., Saunus JM; The University of Queensland Faculty of Medicine, UQ Centre for Clinical Research, Herston, Qld, Australia.

Publikováno v: Therapeutic advances in medical oncology [Ther Adv Med Oncol] 2020 Jul 31; Vol. 12, pp. 1758835920946259. Date of Electronic Publication: 2020 Jul 31 (Print Publication: 2020).