Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kusum P. Lele"'
Autor:
Shu-Yun Li, Michael S. Krawczun, Kusum P. Lele, Sandra L. Stark‐Houck, Hong Gu, Edmund C. Jenkins, Charlotte J. Duncan, Marilyn Genovese
Publikováno v:
American Journal of Medical Genetics. 43:136-141
Cell cultures from 760 whole blood, amniotic fluid, chorionic villus sample, and peripheral umbilical blood sample specimens were exposed to multiple fra(X)(q27.3) induction systems (none had aphidicolin). Fifty-three exhibited the rare fragile site,
Autor:
Victor E. Reuter, Ethan Dmitrovsky, Suresh C. Jhanwar, Felipe Samaniego, R. S. K. Chaganti, Quanguang Chen, Kusum P. Lele, Jane Houldsworth, Nancy L. Geller, George J. Bosl, Eduardo Rodriguez, Marc Ladanyi, Vundavalli V. Murty
Publikováno v:
Genes, Chromosomes and Cancer. 1:289-300
We report karyotypic analysis of 24 male germ cell tumors (GCTs) with clonally abnormal karyotypes biopsied from testicular and extragonadal lesions from 20 patients belonging to the histologic categories seminoma, teratoma, embryonal carcinoma, chor
Autor:
Michael S. Krawczun, Carol Schwartz-Richstein, Maureen M. Sanz, Hong Gu, Mary Lee Salandi, Charlotte J. Duncan, Kusum P. Lele, Edmund C. Jenkins, Marilyn Genovese
Publikováno v:
Pathobiology. 58:236-240
We have been attempting to develop a consistently reliable internal control to assure the effectiveness of the 5-fluorodeoxyuridine (FUdR) fragile-X [fra(X)] induction system. We carried out a systematic study of whole-blood specimens cultured from 5
Autor:
Edmund C. Jenkins, Eugene A. Sersen, Kusum P. Lele, Michael S. Krawczun, Henryk M. Wisniewski
Publikováno v:
Alzheimer disease and associated disorders. 4(4)
Numerous intraneuronal neurofibrillary tangles and senile (neuritic) plaques are the two characteristic lesions in Alzheimer disease (AD) and adult Down syndrome (DS). Evidence indicates that microtubule assembly is impaired in AD. We studied spindle
Autor:
Edmund C. Jenkins, Michael S. Krawczun, W. Ted Brown, James F. Reynolds, Kusum P. Lele, John M. Opitz
Publikováno v:
American Journal of Medical Genetics. 23:467-473
The effect of cell density on expression of fra(X) was studied. A lymphoblast cell line from one fra(X) individual and whole blood from another individual was tested at various cell densities using RPMI-1640 with FUdR (0.1 microM) 24 hrs before harve
Autor:
Mitchell S. Golbus, W. Ted Brown, Charlotte J. Duncan, Suphat Kunaporn, Edmund C. Jenkins, Kusum P. Lele, Steven A. Schonberg, Wayne Silverman, Gurbax S. Sekhon, Sandra Stark, Eduardo S. Cantú, Michael S. Krawczun
Publikováno v:
American Journal of Medical Genetics. 30:329-336
At least 35 cases of prenatal fra(X) diagnosis have been confirmed and reported. Amniotic fluid, fetal blood and chorion -ic villus samples have exhibited fra(X) (q27.3) in cultures from 26 males and 9 females. Here we have detected fra(X) in female
Autor:
M. D'a. Crawfurd, Kusum P. Lele
Publikováno v:
Annals of Human Genetics. 29:199-205
Publikováno v:
British Journal of Cancer
The sensitivity of lymphocytes to chlorambucil has been assessed by a simple in-vitro test which has been applied to the cells of normal controls and of patients with chronic lymphocytic leukaemia. The degree of sensitivity varied amongst the normal
Publikováno v:
Nature. 205:477-479
Relationship of Barr Bodies, Nuclear Size and Deoxyribonucleic Acid Value in Cultured Human Cells
Publikováno v:
Cancer genetics and cytogenetics. 4(4)
Mononuclear cells from peripheral blood and spleen of four patients with hairy cell leukemia (HCL) were cultured for 1 to 10 days with and without phytohemagglutinin (PHA) stimulation. Blastogenesis and mitoses were not observed in the unstimulated c