Ligand Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies of Asymmetrical Hexahydro-2H-Indazole Analogs of Curcumin (AIACs) to Discover Novel Estrogen Receptors Alpha (ERα) Inhibitor

Autor: Kusmadi Kurmardi, Arry Yanuar, Hayun Hayun, Hariyanti Hariyanti

Publikováno v: Indonesian Journal of Chemistry; Vol 21, No 1 (2021); 137-147
Indonesian Journal of Chemistry, Vol 21, Iss 1, Pp 137-147 (2020)

The estrogen receptor alpha (ERα) plays an important role in breast development and pro-proliferation signal activation in the normal and cancerous breast. The ERα inhibitors were potentially active as cytotoxic agents against breast cancer. This s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d3559c6f0f9ae2edd4acb68c7cb6a4
https://journal.ugm.ac.id/ijc/article/view/54745