Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Kusma Pyakurel"'
Autor:
Mohamed A. Ghonim, Jihang Ju, Kusma Pyakurel, Salome V. Ibba, Mai M. Abouzeid, Hamada F. Rady, Shigemi Matsuyama, Luis Del Valle, A. Hamid Boulares
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background The DNA-dependent protein kinase (DNA-PK) complex comprises a catalytic (PRKDC) and two requisite DNA-binding (Ku70/Ku80) subunits. The role of the complex in repairing double-stranded DNA breaks (DSBs) is established, but its rol
Externí odkaz:
https://doaj.org/article/ab21f508a8dd4a0da29878d32d70148d
Autor:
Mohamed A. Ghonim, Jeffrey Wang, Salome V. Ibba, Hanh H. Luu, Kusma Pyakurel, Ilyes Benslimane, Shaker Mousa, A. Hamid Boulares
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background The efficacy of heparins and low-MW-heparins (LMWH) against human asthma has been known for decades. However, the clinical utility of these compounds has been hampered by their anticoagulant properties. Much effort has been put in
Externí odkaz:
https://doaj.org/article/9f367d95146e4c9fafcc7be9fc3fbb45
Autor:
Salome’ V. Ibba, Mohamed A. Ghonim, Kusma Pyakurel, Matthew R. Lammi, Anil Mishra, A. Hamid Boulares
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Although expression of inducible NO synthase (iNOS) in the lungs of asthmatics and associated nitrosative damage are established, iNOS failed as a therapeutic target for blocking airway hyperresponsiveness (AHR) and inflammation in asthmatics. This d
Externí odkaz:
https://doaj.org/article/989c7b6ab1eb435ca527f623bebc0b2e
Autor:
Matthew R. Lammi, Saito Saito, Samuel C. Okpechi, Natalie N. Bauer, Mohamed A. Ghonim, A. Hamid Boulares, Bennett P. deBoisblanc, Lesley Ann Saketkoo, Dorota Wyczechowska, Kusma Pyakurel
Publikováno v:
Respirology. 24:675-683
BACKGROUND AND OBJECTIVE: Endothelial microparticles (EMP) are submicron vesicles released from endothelial cells. We aimed to determine the utility of EMP as bio-markers of pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) patients a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6438c5c3e1a5fc97d1b63d758ee21749
https://doi.org/10.1111/resp.13500
https://doi.org/10.1111/resp.13500
Autor:
A. Hamid Boulares, Samuel C. Okpechi, Judd E. Shellito, Matthew R. Lammi, Connie Romaine, John B. Zamjahn, Hahn H. Luu, Bennett P. deBoisblanc, Jessica L. Johnson, Mohamed A. Ghonim, Andy Pellett, Johnny D'Aquin, Kusma Pyakurel
Publikováno v:
Respir Med
Background and objective We tested whether the prostacyclin analog inhaled iloprost modulates dead space, dynamic hyperinflation (DH), and systemic inflammation/oxidative stress during maximal exercise in subjects with chronic obstructive pulmonary d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a5910459f64fdac6c8b21e3673673b
https://pubmed.ncbi.nlm.nih.gov/33721696
https://pubmed.ncbi.nlm.nih.gov/33721696
Autor:
Ilyes Benslimane, Mohamed A. Ghonim, A. Hamid Boulares, Hanh H Luu, Shaker A. Mousa, Jeffrey Wang, Salome V. Ibba, Kusma Pyakurel
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Journal of Translational Medicine
Journal of Translational Medicine
Background The efficacy of heparins and low-MW-heparins (LMWH) against human asthma has been known for decades. However, the clinical utility of these compounds has been hampered by their anticoagulant properties. Much effort has been put into harnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf48aa3f6f1e50b94a2e0f4ac001136
http://link.springer.com/article/10.1186/s12967-018-1621-5
http://link.springer.com/article/10.1186/s12967-018-1621-5
Autor:
Jeffrey C. Wang, Mohamed A. Ghonim, Salome V. Ibba, Matthew R. Lammi, Hamid Boulares, Kusma Pyakurel
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e2b10b67732a9b064ae8f4162761464
https://doi.org/10.1096/fasebj.2018.32.1_supplement.686.16
https://doi.org/10.1096/fasebj.2018.32.1_supplement.686.16
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::560c1279c16318976a2cf5f453ff5fe6
https://doi.org/10.1096/fasebj.2018.32.1_supplement.570.2
https://doi.org/10.1096/fasebj.2018.32.1_supplement.570.2
Autor:
Moselhy S Mansy, Christian Davis, Mohamed A. Ghonim, Kusma Pyakurel, Paulo C. Rodriguez, A. Hamid Boulares, Matthew R. Lammi, Amarjit S. Naura, Mohammad Q. Abughazleh, Jihang Ju
Publikováno v:
Journal of Allergy and Clinical Immunology. 135:425-440
Background We reported that DNA-dependent protein kinase (DNA-PK) is critical for the expression of nuclear factor κB–dependent genes in TNF-α–treated glioblastoma cells, suggesting an involvement in inflammatory diseases. Objective We sought t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4918a539f38c843e9f74118093d52726
https://doi.org/10.1016/j.jaci.2014.09.005
https://doi.org/10.1016/j.jaci.2014.09.005
Autor:
Augusto C. Ochoa, Liqin Zheng, L. Del Valle, Maria Dulfary Sanchez-Pino, Amir A. Al-Khami, Jone Garay, Samuel C. Okpechi, A. H. Boulares, Salome V. Ibba, Paulo C. Rodriguez, Dorota Wyczechowska, Mohamed A. Ghonim, Kusma Pyakurel
Background Increasing evidence has shown the close link between energy metabolism and the differentiation, function, and longevity of immune cells. Chronic inflammatory conditions such as parasitic infections and cancer trigger a metabolic reprogramm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6214e6c0a6feda2ea0a0394f62173b
https://europepmc.org/articles/PMC5578913/
https://europepmc.org/articles/PMC5578913/
