Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kushtrim Kryeziu"'
Autor:
Anita Sveen, Bjarne Johannessen, Ina A. Eilertsen, Bård I. Røsok, Marie Gulla, Peter W. Eide, Jarle Bruun, Kushtrim Kryeziu, Leonardo A. Meza-Zepeda, Ola Myklebost, Bjørn A. Bjørnbeth, Rolf I. Skotheim, Arild Nesbakken, Ragnhild A. Lothe
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract Background Colorectal cancer is the 2nd leading cause of cancer-related deaths with few patients benefiting from biomarker-guided therapy. Mutation expression is essential for accurate interpretation of mutations as biomarkers, but surprisin
Externí odkaz:
https://doaj.org/article/b34b58a9f5234132b5b1362c2f2bb886
Autor:
Kushtrim Kryeziu, Seyed H. Moosavi, Christian H. Bergsland, Marianne G. Guren, Peter W. Eide, Max Z. Totland, Kristoffer Lassen, Andreas Abildgaard, Arild Nesbakken, Anita Sveen, Ragnhild A. Lothe
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Tumor heterogeneity is a primary cause of treatment failure. However, changes in drug sensitivity over time are not well mapped in cancer. Patient-derived organoids (PDOs) may predict clinical drug responses ex vivo and offer an opportunity
Externí odkaz:
https://doaj.org/article/ae8e4589a2914bc0acf2c8d31711cf45
Autor:
Jørgen Smeby, Kushtrim Kryeziu, Kaja C.G. Berg, Ina A. Eilertsen, Peter W. Eide, Bjarne Johannessen, Marianne G. Guren, Arild Nesbakken, Jarle Bruun, Ragnhild A. Lothe, Anita Sveen
Publikováno v:
EBioMedicine, Vol 59, Iss , Pp 102923- (2020)
Background: PARP inhibitors are active in various tumour types beyond BRCA-mutant cancers, but their activity and molecular correlates in colorectal cancer (CRC) are not well studied. Methods: Mutations and genome-wide mutational patterns associated
Externí odkaz:
https://doaj.org/article/aa799509497e47aca84342bd1349c228
Autor:
Walter Berger, Balazs Hegedüs, Michael Grusch, Balazs Döme, Walter Klepetko, Judit Ozsvar, Anita Rozsas, Viktoria Laszlo, Thomas Klikovits, Sushilla van Schoonhoven, Kushtrim Kryeziu, Petra Heffeter, Karin Schelch, Yawen Dong, Christine Pirker, Mir A. Hoda
Supplementary Figure S1: Sensitivity of pleural mesothelioma cell models to trabectedin and impact of the histological origin Supplementary Figure S2: Impact of trabectedin on the migratory potential of pleural mesothelioma cell models Supplementary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94caab1f76b3f8eb6ba5fadcf8311df
https://doi.org/10.1158/1535-7163.22504230.v1
https://doi.org/10.1158/1535-7163.22504230.v1
Autor:
Petra Heffeter, Walter Berger, Christian R. Kowol, Claudia Karnthaler-Benbakka, Siegfried Knasmüller, Franziska Ferk, Mir Alireza Hoda, Ute Jungwirth, Kushtrim Kryeziu
PDF File - 512K, Solid cancer cell lines and their genetic characteristics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a5ccc368ce561c2be90e6c3902fc2b
https://doi.org/10.1158/1535-7163.22500231
https://doi.org/10.1158/1535-7163.22500231
Autor:
Walter Berger, Balazs Hegedüs, Michael Grusch, Balazs Döme, Walter Klepetko, Judit Ozsvar, Anita Rozsas, Viktoria Laszlo, Thomas Klikovits, Sushilla van Schoonhoven, Kushtrim Kryeziu, Petra Heffeter, Karin Schelch, Yawen Dong, Christine Pirker, Mir A. Hoda
Supplementary Table S1: Source, background, histology of the tumor and sensitivity towards trabectedin and cisplatin of all mesothelial and mesothelioma cell models used Supplementary Table S2: Cell death-related genes most differently expressed betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a91be2084472e9525e0b201853efdb
https://doi.org/10.1158/1535-7163.22504227.v1
https://doi.org/10.1158/1535-7163.22504227.v1
Autor:
Petra Heffeter, Walter Berger, Christian R. Kowol, Claudia Karnthaler-Benbakka, Siegfried Knasmüller, Franziska Ferk, Mir Alireza Hoda, Ute Jungwirth, Kushtrim Kryeziu
Arsenic trioxide (ATO), one of the oldest remedies used in traditional medicine, was recently rediscovered as an anticancer drug and approved for treatment of relapsed acute promyelocytic leukemia. However, its activity against nonhematologic cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921d3a6d55fd7557f0544ebc590eafa9
https://doi.org/10.1158/1535-7163.c.6536400.v1
https://doi.org/10.1158/1535-7163.c.6536400.v1
Autor:
Walter Berger, Balazs Hegedüs, Michael Grusch, Balazs Döme, Walter Klepetko, Judit Ozsvar, Anita Rozsas, Viktoria Laszlo, Thomas Klikovits, Sushilla van Schoonhoven, Kushtrim Kryeziu, Petra Heffeter, Karin Schelch, Yawen Dong, Christine Pirker, Mir A. Hoda
Trabectedin synergizes with the bcl-2 inhibitor obatoclax in a pleural mesothelioma cell model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58af23d12bd25d099689059d11f5849
https://doi.org/10.1158/1535-7163.22504224.v1
https://doi.org/10.1158/1535-7163.22504224.v1
Autor:
Ragnhild A. Lothe, Anita Sveen, Bjørn Atle Bjørnbeth, Arild Nesbakken, Marianne G. Guren, Rodrigo Dienstmann, Tormod Guren, Kristoffer W. Brudvik, Hector G. Palmer, Christian H. Bergsland, Jani Saarela, Teijo Pellinen, Tuva H. Brunsell, Max Z. Totland, Bård Røsok, Jonas Langerud, Ina A. Eilertsen, Seyed H. Moosavi, Peter W. Eide, Kushtrim Kryeziu, Jarle Bruun
Purpose:Molecular tumor heterogeneity may have important implications for the efficacy of targeted therapies in metastatic cancers. Inter-metastatic heterogeneity of sensitivity to anticancer agents has not been well explored in colorectal cancer.Exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c638067b84c7e740fe78cc2152fa3e5
https://doi.org/10.1158/1078-0432.c.6529418.v1
https://doi.org/10.1158/1078-0432.c.6529418.v1
Autor:
Ragnhild A. Lothe, Rodrigo Dienstmann, Olli Kallioniemi, Arild Nesbakken, Hector G. Palmer, Justin Guinney, Josep Tabernero, Elena Elez, Kushtrim Kryeziu, Stine A. Danielsen, Mariliina Arjama, Astrid Murumägi, Lorena Ramirez, Ina A. Eilertsen, Peter W. Eide, Jarle Bruun, Anita Sveen
This file contains Supplementary Text, Supplementary Figures S1-S13 and Supplementary Tables S1, S3-S5, S9-S10, S14-S15, S18-S19. Supplementary Fig. S1. Validation of prognostic associations and biological properties of the CMS groups in primary CRCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bf8ad6d43f2581b4030510cc4eccf8
https://doi.org/10.1158/1078-0432.22464177
https://doi.org/10.1158/1078-0432.22464177