Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kushari Burns"'
Autor:
Nuy Chau, Kushari Burns, John O. Miners, Ross A. McKinnon, Kathleen M. Knights, Andrew Rowland, Geoffrey T. Tucker, Peter I. Mackenzie, Ganessan Kichenadasse
Publikováno v:
Biochemical Pharmacology. 129:85-95
Kinase inhibitors (KIs) are a rapidly expanding class of drugs used primarily for the treatment of cancer. Data relating to the inhibition of UDP-glucuronosyltransferase (UGT) enzymes by KIs is sparse. However, lapatinib (LAP), pazopanib (PAZ), regor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e959039998f63e56349d6ee9b92dc7
https://doi.org/10.1016/j.bcp.2017.01.002
https://doi.org/10.1016/j.bcp.2017.01.002
Autor:
Kushari Burns, Sandra L. Peake, John O. Miners, John L. Moran, Andrew Rowland, Patricia Williams, S. J. Kelly
Publikováno v:
Anaesthesia. 71(10)
Summary Paracetamol is a commonly used drug in the intensive care unit. There have been reports in the literature of an association with significant hypotension, a potentially important interaction for labile critically ill patients. Route of adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9903e850f940bf5c97705e73702b5436
https://pubmed.ncbi.nlm.nih.gov/27988955
https://pubmed.ncbi.nlm.nih.gov/27988955
Autor:
Kathleen M. Knights, Peter I. Mackenzie, John O. Miners, Andrew Rowland, Pramod C. Nair, Kushari Burns
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 43(12)
Drugs and other chemicals frequently bind nonspecifically to the constituents of an in vitro incubation mixture, particularly the enzyme source [e.g., human liver microsomes (HLM)]. Correction for nonspecific binding (NSB) is essential for the accura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4aa0b9a3ded48326d42b5248cf9aea
https://pubmed.ncbi.nlm.nih.gov/26443648
https://pubmed.ncbi.nlm.nih.gov/26443648
Autor:
Peter I. Mackenzie, Nuy Chau, John O. Miners, Kushari Burns, Porntipa Korprasertthaworn, Andrew Rowland, Kathleen M. Knights
Publikováno v:
Drug Metabolism and Pharmacokinetics. 32:S53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a6553b4340fc250c0bdf2eb6cd83fc
https://doi.org/10.1016/j.dmpk.2016.10.220
https://doi.org/10.1016/j.dmpk.2016.10.220
Autor:
Kushari Burns, Benjamin C. Lewis, David J. Elliot, John O. Miners, Nuy Chau, Peter I. Mackenzie, Martin R. Johnston
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 349(1)
Morphine 3-β-D-glucuronide (M3G) and morphine 6-β-D-glucuronide (M6G) are the major metabolites of morphine in humans. More recently, morphine-3-β-d-glucoside (M-3-glucoside) was identified in the urine of patients treated with morphine. Kinetic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec39dc7e3b8e8742dac8fbed0045885
https://pubmed.ncbi.nlm.nih.gov/24459244
https://pubmed.ncbi.nlm.nih.gov/24459244