Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kushal Garima"'
Autor:
Naresh Kumar Sharma, Nisha Rathor, Rajesh Sinha, Shraddha Gupta, Gaurav Tyagi, Kushal Garima, Rakesh Pathak, Pooja Singh, Ashima Jain, Mridula Bose, Mandira Varma-Basil
Publikováno v:
International Journal of Mycobacteriology, Vol 8, Iss 3, Pp 237-243 (2019)
Background: Extrapulmonary tuberculosis (EPTB), accounting for 10%–20% of all cases of tuberculosis (TB), is known to be determined by host immunity. However, the contribution of bacterial factors to the development of EPTB has not been studied ext
Externí odkaz:
https://doaj.org/article/eeae0baa87f44a78b4d461198235319f
Publikováno v:
International Journal of Mycobacteriology, Vol 6, Iss 2, Pp 177-183 (2017)
Background: Isoniazid (INH) resistance in Mycobacterium tuberculosis has been mainly attributed to mutations in katG (64%) and inhA (19%). However, 20%–30% resistance to INH cannot be explained by mutations alone. Hence, other mechanisms besides mu
Externí odkaz:
https://doaj.org/article/f347d26031634bfa80df21bd9b4968cd
Autor:
Anshika Narang, Kushal Garima, Shraddha Porwal, Archana Bhandekar, Kamal Shrivastava, Astha Giri, Naresh Kumar Sharma, Mridula Bose, Mandira Varma-Basil
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0223163 (2019)
Despite the consideration of chromosomal mutations as the major cause of rifampicin (RIF) resistance in M. tuberculosis, the role of other mechanisms such as efflux pumps cannot be ruled out. We evaluated the role of four efflux pumps viz., MmpL2 (Rv
Externí odkaz:
https://doaj.org/article/c6686f431a4f44e8ad4585f0dd83e8f6
Autor:
Nisha Rathor, Kushal Garima, Naresh Kumar Sharma, Anshika Narang, Mandira Varma-Basil, Mridula Bose
Publikováno v:
International Journal of Mycobacteriology, Vol 5, Iss 3, Pp 328-332 (2016)
Background: The mce4 operon is one of the four mce operons with eight genes ( yrbE4A , yrbE4B , mce4A, mce4B, mce4C, mce4D, mce4E and mce4F) of Mycobacterium tuberculosis. It expresses in the later phase of infection and imports cholesterol for long
Externí odkaz:
https://doaj.org/article/bfcdec7d97a940cb93b45f13d569e731
Autor:
Kushal Garima, Mandira Varma-Basil, Rakesh Pathak, Sujeet Kumar, Anshika Narang, Khushal Singh Rawat, Anil Chaudhry, Deepthi Nair, V G Ramachandran, Mridula Bose
Publikováno v:
International Journal of Mycobacteriology, Vol 1, Iss 4, Pp 207-211 (2012)
A large number of potentially pathogenic non-tuberculous mycobacteria (NTM) encountered in the clinical laboratory makes it necessary to identify their species to ensure appropriate treatment. However, labor-intensive conventional methods of speciati
Externí odkaz:
https://doaj.org/article/4b4b42557e8b460082a33c5f25495b72
Autor:
Ashima Jain, Naresh Kumar Sharma, Mandira Varma-Basil, Nisha Rathor, Shraddha Gupta, Pooja Singh, Kushal Garima, Rakesh Pathak, Rajesh Sinha, Mridula Bose, Gaurav Tyagi
Publikováno v:
International Journal of Mycobacteriology, Vol 8, Iss 3, Pp 237-243 (2019)
Background: Extrapulmonary tuberculosis (EPTB), accounting for 10%–20% of all cases of tuberculosis (TB), is known to be determined by host immunity. However, the contribution of bacterial factors to the development of EPTB has not been studied ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5934b8286f8a7073dc5df95b855c3e
http://www.ijmyco.org/article.asp?issn=2212-5531
http://www.ijmyco.org/article.asp?issn=2212-5531
Autor:
Roshan Kumar Singh, Rajendra Prasad, Kamal Shrivastava, Anshika Narang, Mandira Varma-Basil, Anil Chaudhry, Ekta Vishnoi, Kushal Garima, K K Bhattacharyya, Mridula Bose
Publikováno v:
Journal of Medical Microbiology. 66:371-376
Purpose. We explored the efficiency of Rv1458c, the gene encoding a putative ABC drug transporter specific for the Mycobacterium tuberculosis complex (MTBC), as a diagnostic marker. Methodology. A 190 bp region of Rv1458c and a 300 bp region of hsp65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8679a55933cc8e2a3237f071478a5fb
https://doi.org/10.1099/jmm.0.000440
https://doi.org/10.1099/jmm.0.000440
Autor:
Rakesh Pathak, Naresh Kumar Sharma, Kushal Garima, Nisha Rathor, Mandira Varma-Basil, Pooja Singh, Mridula Bose
Publikováno v:
Gene. 560:57-62
Lipoprotein signal peptidase, lspA (Rv1539), is the only known gene in mycobacterial genome for cleaving the signal sequence from prolipoprotein to form mature lipoprotein. It has been implicated in maintaining the virulence of Mycobacterium tubercul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12abe430857186e8b418da3d0d0a3763
https://doi.org/10.1016/j.gene.2015.01.061
https://doi.org/10.1016/j.gene.2015.01.061
Autor:
Neeraj K. Saini, Mridula Bose, Ashok K. Prasad, Pooja Singh, Rakesh Pathak, Ajit Kumar, Hanumantharao G. Raj, Amita Chandolia, Rajesh Sinha, Kushal Garima, Madhu Chopra, Gaurav Tyagi
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 109
Cholesterol, an essential cellular component in macrophages, is exploited for entry and long-term survival of Mycobacterium inside the host. Cholesterol-deficient macrophages can restrict the cholesterol-dependent entry of Mycobacterium. Rv3499c prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e6eb1ae098794323bc96d57ffa4d39
https://pubmed.ncbi.nlm.nih.gov/29559121
https://pubmed.ncbi.nlm.nih.gov/29559121
Autor:
Kushal Garima, Shraddha Porwal, Archana Bhandekar, Kamal Shrivastava, Anshika Narang, Mridula Bose, Astha Giri, Naresh Kumar Sharma, Mandira Varma-Basil
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0223163 (2019)
PLoS ONE
PLoS ONE
Despite the consideration of chromosomal mutations as the major cause of rifampicin (RIF) resistance in M. tuberculosis, the role of other mechanisms such as efflux pumps cannot be ruled out. We evaluated the role of four efflux pumps viz., MmpL2 (Rv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70965f32befd09209d87527ee3b0f925
https://doi.org/10.1371/journal.pone.0223163
https://doi.org/10.1371/journal.pone.0223163