Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kush, Ruparelia"'
Autor:
William McCabe, Kush Ruparelia, Howard Thomas, M. Ali, Quentin M. Anstee, Susanne Knapp, Andrew McQuillin, Michael J. Way, Marsha Y. Morgan
Publikováno v:
Psychiatric Genetics. 27:110-115
Associations between the γ-aminobutyric acid type-A receptors (GABAA) and alcohol dependence risk have been reported, although the receptor subunit driving the association is unclear. Recent work in mice has highlighted a possible role for variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ac100c244c71e64df6532950600228
https://doi.org/10.1097/ypg.0000000000000169
https://doi.org/10.1097/ypg.0000000000000169
Autor:
Shamir Patel, Sameer Jauhar, Irene Guerrini, Sally I. Sharp, Michael J. Way, David Curtis, Marsha Y. Morgan, Sherhzad Yameen Qureshi, Iain Smith, Gerry Reynolds, Radhika Kandaswamy, Karim Dar, Audrey Hillman, Girija Kottalgi, Harish Rao, David Ball, Aideen O’Kane, Alex Dedman, Gregory J Lydall, Ewen Douglas, Hugh Gurling, Allan D. Thomson, Raquin Cherian, Andrew McQuillin, Giorgia Quadri, Jit Saini, Kush Ruparelia, Priyanthi Gunwardena, Katherine Kasiakogia-Worlley
Publikováno v:
Addiction Biology. 20:594-604
Certain single nucleotide polymorphisms (SNPs) in genes encoding alcohol dehydrogenase (ADH) enzymes confer a significant protective effect against alcohol dependence syndrome (ADS) in East Asian populations. Recently, attention has focused on the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32e4fc933876b16fad71cf8fee9f1084
https://doi.org/10.1111/adb.12141
https://doi.org/10.1111/adb.12141
Autor:
Michael, Way, Andrew, McQuillin, Jit, Saini, Kush, Ruparelia, Gregory J, Lydall, Irene, Guerrini, David, Ball, Iain, Smith, Giorgia, Quadri, Allan D, Thomson, Katherine, Kasiakogia-Worlley, Raquin, Cherian, Priyanthi, Gunwardena, Harish, Rao, Girija, Kottalgi, Shamir, Patel, Audrey, Hillman, Ewen, Douglas, Sherhzad Y, Qureshi, Gerry, Reynolds, Sameer, Jauhar, Aideen, O'Kane, Alex, Dedman, Sally, Sharp, Radhika, Kandaswamy, Karim, Dar, David, Curtis, Marsha Y, Morgan, Hugh M D, Gurling
Publikováno v:
Addiction biology. 20(3)
Certain single nucleotide polymorphisms (SNPs) in genes encoding alcohol dehydrogenase (ADH) enzymes confer a significant protective effect against alcohol dependence syndrome (ADS) in East Asian populations. Recently, attention has focused on the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1de76341317aca840ca80773ee0e551d
https://pubmed.ncbi.nlm.nih.gov/24735490
https://pubmed.ncbi.nlm.nih.gov/24735490
Autor:
Sophie E. Walker, Jeremy J. Lambert, Alastair M. Hosie, Steve D.M. Brown, Delia Belelli, Quentin M. Anstee, Irene Guerrini, Jimmy D. Bell, Edward P. Maguire, Yu-Ting Kuo, Sara Montagnese, Elizabeth M. C. Fisher, Amy H. Herlihy, Kush Ruparelia, Marsha Y. Morgan, Susanne Knapp, Philip Thomas, Trevor G. Smart, Claire I. Dixon, Howard C. Thomas, Martin Mortensen, Iain C. A. F. Robinson, Mark A. Ungless, Alonso Martínez, Rohan Bhome, Hugh Gurling, Andrew McQuillin, David N. Stephens
Publikováno v:
Nature communications
Alcohol dependence is a common, complex and debilitating disorder with genetic and environmental influences. Here we show that alcohol consumption increases following mutations to the γ-aminobutyric acidA receptor (GABAAR) β1 subunit gene (Gabrb1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fdf694b5cc08c71741615ead291012
http://ora.ox.ac.uk/objects/uuid:41b33393-0658-45d9-b3b6-c00cf26028b2
http://ora.ox.ac.uk/objects/uuid:41b33393-0658-45d9-b3b6-c00cf26028b2
Autor:
Sara Montagnese, Irene Guerrini, Kush Ruparelia, Gerry Reynolds, Hugh Gurling, Andrew McQuillin, Marsha Y. Morgan, Iain Smith, Jit Saini, Allan D. Thomson, Gregory J Lydall, H. Rao, David Ball
The gamma aminobutyric acid (GABA) system has been implicated in the susceptibility to develop alcohol dependence and in determining electroencephalogram (EEG) beta activity. The role of the GABA receptor alpha-2 gene (GABRA2) in human alcohol depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff0f475475ef42580dc0a93ddbbe839
http://hdl.handle.net/11577/2503570
http://hdl.handle.net/11577/2503570
Autor:
Girija Kottalgi, Michael J. Way, Katherine Kasiakogia-Worlley, Irene Guerrini, Aideen O’Kane, Sherzhad Y. Qureshi, Kush Ruparelia, David Curtis, Hugh Gurling, Radhika Kandaswamy, Marsha Y. Morgan, Sameer Jauhar, Sally I. Sharp, Andrew McQuillin, Iain Smith, Allan D. Thomson, Raquin Cherian, Audrey Hillman, David Ball, Karim Dar, Ewen Douglas, Gerry Reynolds, Harish Rao, Giorgia Quadri, Jit Saini, G. Lydall, Shamir Patel, Priyanthi Gunawardena
Publikováno v:
Psychiatric Genetics
The risk for developing the alcohol dependence syndrome (ADS) has a substantial genetic component. The human thiamine transporter protein 2 (hTHTR2) is encoded by the SLC19A3 gene, which is on chromosome 2q37. hTHTR2 is responsible for the cellular u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ceef15db2c665a3e4a75a113d2fea24
https://doi.org/10.1097/ypg.0000000000000025
https://doi.org/10.1097/ypg.0000000000000025