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pro vyhledávání: '"Kusano-Kitazume A"'
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Autor:
Takako Watanabe, Mina Nakagawa, Satoshi Otani, Mamoru Watanabe, Fumio Goto, Miki Taniguchi, Fukiko Kawai-Kitahata, Sayuri Nitta, Naoya Sakamoto, Yuki Nishimura-Sakurai, Sei Kakinuma, Yasuhiro Asahina, Akiko Kusano-Kitazume, Miyako Murakawa, Yasuhiro Itsui, Seishin Azuma
Publikováno v:
Journal of Gastroenterology and Hepatology. 30:1075-1084
Background and Aim Interferon (IFN) λ plays an important role in innate immunity to protect against hepatitis C viral (HCV) infection. Single nucleotide polymorphisms (SNPs) near IL28B (IFNλ3) are strongly associated with treatment response to IFN
Autor:
Hiromitsu Nakauchi, Naoya Sakamoto, Hiromichi Shimizu, Sei Kakinuma, Naoki Tanimizu, Mamoru Watanabe, Ryuichi Okamoto, Akira Kikuchi, Hideto Yamanaka, Mina Nakagawa, Yasuhiro Asahina, Kouhei Yoshino, Akiko Kusano-Kitazume, Junko Fujiki, Seishin Azuma, Akihide Kamiya, Sayuri Nitta, Kei Kiyohashi, Miyako Murakawa
Publikováno v:
Hepatology. 57:2502-2513
The molecular mechanisms regulating differentiation of fetal hepatic stem/progenitor cells, called hepatoblasts, which play pivotal roles in liver development, remain obscure. Wnt signaling pathways regulate the development and differentiation of ste
Autor:
Mamoru Watanabe, Megumi Tasaka-Fujita, Kako Mishima, Naoya Sakamoto, Miyako Murakawa, Yasuhiro Asahina, Mina Nakagawa, Takashi Fujita, Sayuri Nitta, Sei Kakinuma, Mitsutoshi Yoneyama, Yuki Nishimura-Sakurai, Seishin Azuma, Kei Kiyohashi, Akiko Kusano-Kitazume
Publikováno v:
Hepatology. 57:46-58
Hepatitis C virus (HCV) infection blocks cellular interferon (IFN)-mediated antiviral signaling through cleavage of Cardif by HCV-NS3/4A serine protease. Like NS3/4A, NS4B protein strongly blocks IFN-β production signaling mediated by retinoic acid
Autor:
Izumi Onozuka, Mamoru Watanabe, Seishin Azuma, Takako Watanabe, Yuki Nishimura-Sakurai, Miyako Murakawa, Sei Kakinuma, Kei Kiyohashi, Masashi Mizokami, Sayuri Nitta, Yasuhito Tanaka, Akiko Kusano-Kitazume, Kohei Yoshino, Naoya Sakamoto, Yasuhiro Itsui, Mina Nakagawa
Publikováno v:
Hepatology International. 7:153-161
Genetic variation leading to inosine triphosphatase (ITPA) deficiency protects chronic hepatitis C patients receiving ribavirin against hemolytic anemia. The relationship between ITPA gene variation and serum ribavirin concentration was analyzed in a
Autor:
Akiko, Kusano-Kitazume, Katsunori, Ami, Takeshi, Nagahama, Mayumi, Kondo, Eiko, Okamoto, Atsushi, Tamura, Kentaro, Takagi, Junnosuke, Hayasaka, Ayako, Watanabe, Yosuke, Kawai, Keiichi, Fujiya, Hidetoshi, Amagasa, Hideaki, Ganno, Kenichiro, Imai, Akira, Fukuda, Masayuki, Ando, Kuniyoshi, Arai, Takao, Shibayama
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 41(12)
Use of a standard open stent or self-expanding metal stent for patients with malignant dysphagia is associated with a risk of gastroesophageal reflux especially when placed across the esophagogastric junction. We report 3 cases of malignant esophagea
Autor:
Eiko, Okamoto, Jun, Sato, Manabu, Sema, Junnosuke, Hayasaka, Ayako, Watanabe, Kentaro, Takagi, Akiko, Kusano-Kitazume, Atsushi, Tamura, Mayumi, Kondo, Haruyasu, Sakuranaka, Junichi, Ochi, Satoko, Hanada, Michiko, Tanaka, Hidetaka, Akita, Shikofumi, Tei, Masahiko, Ichioka, Takao, Shibayama
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 41(12)
A 78-year-old man presented to our hospital with lung abnormality on his chest radiograph. Computed tomography (CT) showed a mass and obstructive pneumonia in the right upper lobe of the lung. The mass was diagnosed as a pulmonary adenocarcinoma with
Autor:
Kentaro, Takagi, Atsushi, Tamura, Junnosuke, Hayasaka, Ayako, Watanabe, Eiko, Okamoto, Akiko, Kusano-Kitazume, Mayumi, Kondo, Takao, Shibayama, Yutaka, Suenobu, Yoshiko, Ohtaka, Hidetaka, Akita, Shikofumi, Tei
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 41(12)
A standard treatment for primary peritoneal carcinoma has not been established to date. We describe a case in which this cancer was successfully treated by use of paclitaxel and carboplatin chemotherapy.An 80-year-old woman who presented with abdomin
Autor:
Miyako, Murakawa, Yasuhiro, Asahina, Mina, Nakagawa, Naoya, Sakamoto, Sayuri, Nitta, Akiko, Kusano-Kitazume, Takako, Watanabe, Fukiko, Kawai-Kitahata, Satoshi, Otani, Miki, Taniguchi, Fumio, Goto, Yuki, Nishimura-Sakurai, Yasuhiro, Itsui, Seishin, Azuma, Sei, Kakinuma, Mamoru, Watanabe
Publikováno v:
Journal of gastroenterology and hepatology. 30(6)
Interferon (IFN) λ plays an important role in innate immunity to protect against hepatitis C viral (HCV) infection. Single nucleotide polymorphisms (SNPs) near IL28B (IFNλ3) are strongly associated with treatment response to IFNα therapy in chroni
Autor:
Naoya Sakamoto, Miyako Murakawa, Akiko Kusano-Kitazume, Yuko Sekine-Osajima, Sei Kakinuma, Sayuri Nitta, Yuki Nishimura-Sakurai, Mina Nakagawa, Mamoru Watanabe, Seishin Azuma, Yukiko Okuno, Masatoshi Hagiwara, Kei Kiyohashi
Publikováno v:
Antimicrobial agents and chemotherapy. 56(3)
To identify novel compounds that possess antiviral activity against hepatitis C virus (HCV), we screened a library of small molecules with various amounts of structural diversity using an HCV replicon-expressing cell line and performed additional val