Asparagine synthetase activity in paediatric acute leukaemias:AML-M5 subtype shows lowest activity

Autor: Dübbers, A., Würthwein, G., Müller, H. J., Schulze-Westhoff, P., Winkelhorst, M., Kurzknabe, E., Lanvers, C., Pieters, R., Kaspers, G. J.L., Creutzig, U., Ritter, J., Boos, J.

Publikováno v: Dübbers, A, Würthwein, G, Müller, H J, Schulze-Westhoff, P, Winkelhorst, M, Kurzknabe, E, Lanvers, C, Pieters, R, Kaspers, G J L, Creutzig, U, Ritter, J & Boos, J 2000, ' Asparagine synthetase activity in paediatric acute leukaemias : AML-M5 subtype shows lowest activity ', British Journal of Haematology, vol. 109, no. 2, pp. 427-429 . https://doi.org/10.1046/j.1365-2141.2000.02015.x
British Journal of Haematology, 109(2), 427-429. Wiley-Blackwell

Lack of sufficient cellular activity of asparagine synthetase (AS) in blast cells compared with normal tissue is thought to be the basis of the antileukaemic effect of L-asparaginase in acute lymphoblastic leukaemia (ALL). Although L-asparaginase is

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A novel type IIb L-asparaginase from Latilactobacillus sakei LK-145: characterization and application.

Autor: Kato S; Faculty of Agriculture, Kagawa University, 2393 Ikenobe, Miki, Kagawa, 761-0795, Japan., Tamura K; Department of Life Science and Biotechnology, Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 Yamate-cho, Suita, Osaka-fu, 564-8680, Japan., Masuda Y; Department of Microbiological Chemistry, Kobe Pharmaceutical University, 4-9-1 Motoyamakita-machi, Higashinada-ku, Kobe, Hyougo, 658-8558, Japan., Konishi M; Department of Microbiological Chemistry, Kobe Pharmaceutical University, 4-9-1 Motoyamakita-machi, Higashinada-ku, Kobe, Hyougo, 658-8558, Japan., Yamanaka K; Department of Life Science and Biotechnology, Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 Yamate-cho, Suita, Osaka-fu, 564-8680, Japan., Oikawa T; Department of Life Science and Biotechnology, Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 Yamate-cho, Suita, Osaka-fu, 564-8680, Japan. oikawa@kansai-u.ac.jp.

Publikováno v: Archives of microbiology [Arch Microbiol] 2024 May 18; Vol. 206 (6), pp. 266. Date of Electronic Publication: 2024 May 18.

Improved pharmacokinetic and pharmacodynamic profile of a novel PEGylated native Erwinia chrysanthemi L-Asparaginase.

Autor: Modi, Tapasvi, Gervais, David

Publikováno v: Investigational New Drugs; Feb2022, Vol. 40 Issue 1, p21-29, 9p

Novel Insights on the Use of L-Asparaginase as an Efficient and Safe Anti-Cancer Therapy.

Autor: Van Trimpont, Maaike^1,2,3 (AUTHOR) maaike.vantrimpont@ugent.be, Peeters, Evelien^1,3,4 (AUTHOR) evelien.peeters@ugent.be, De Visser, Yanti^1,2,5 (AUTHOR) yanti.devisser@kuleuven.be, Schalk, Amanda M.⁶ (AUTHOR) aschalk@uic.edu, Mondelaers, Veerle⁷ (AUTHOR) veerle.mondelaers@uzgent.be, De Moerloose, Barbara^1,7,8 (AUTHOR) barbara.demoerloose@uzgent.be, Lavie, Arnon^6,9 (AUTHOR) lavie@uic.edu, Lammens, Tim^1,7,8 (AUTHOR) tim.lammens@ugent.be, Goossens, Steven^1,3 (AUTHOR) steven.goossens@ugent.be, Van Vlierberghe, Pieter^1,2 (AUTHOR) pieter.vanvlierberghe@ugent.be

Publikováno v: Cancers. Feb2022, Vol. 14 Issue 4, p902. 1p.