Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Kurt W. Fisher"'
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Nonalcoholic fatty liver disease affects about 24% of the world’s population and may progress to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma (HCC). While more common in those that are obese, NASH
Externí odkaz:
https://doaj.org/article/3b96f23dce634ed9b4ad93f8c5d87f5c
Publikováno v:
PLoS ONE, Vol 17, Iss 8 (2022)
Background Non-alcoholic fatty liver disease (NAFLD) ranks first among liver diseases in Western countries. NAFLD is typically associated with obesity and diabetes, however it also develops in lean individuals without metabolic syndrome. The prevalen
Externí odkaz:
https://doaj.org/article/940dd71f871c4fa9a330a52289934cd0
Autor:
Danielle E. Frodyma, Thomas C. Troia, Chaitra Rao, Robert A. Svoboda, Jordan A. Berg, Dhananjay D. Shinde, Vinai C. Thomas, Robert E. Lewis, Kurt W. Fisher
Publikováno v:
Cancers, Vol 14, Iss 19, p 4879 (2022)
Background: Previous studies have shown that Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 Beta (PGC-1β) and Estrogen-Related Receptor Alpha (ERRα) are over-expressed in colorectal cancer and promote tumor survival. Methods: In th
Externí odkaz:
https://doaj.org/article/f97cbc59fc9241f5b8226676d42e6ca0
Autor:
Beth K. Neilsen, Binita Chakraborty, Jamie L. McCall, Danielle E. Frodyma, Richard L. Sleightholm, Kurt W. Fisher, Robert E. Lewis
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background KMT2/MLL proteins are commonly overexpressed or mutated in cancer and have been shown to support cancer maintenance. These proteins are responsible for methylating histone 3 at lysine 4 and promoting transcription and DNA synthesi
Externí odkaz:
https://doaj.org/article/771d20c48057472cbc341e4bbb5bf0ab
Autor:
Chaitra Rao, Dianna H. Huisman, Heidi M. Vieira, Danielle E. Frodyma, Beth K. Neilsen, Binita Chakraborty, Suzie K. Hight, Michael A. White, Kurt W. Fisher, Robert E. Lewis
Publikováno v:
Cancers, Vol 12, Iss 11, p 3143 (2020)
Genome-wide, loss-of-function screening can be used to identify novel vulnerabilities upon which specific tumor cells depend for survival. Functional Signature Ontology (FUSION) is a gene expression-based high-throughput screening (GE-HTS) method tha
Externí odkaz:
https://doaj.org/article/eeb7c3c2153f4bf692228d9922603001
Autor:
Laura L. Ulmer, Ian Cormier, Lokesh K. Jha, Shailender Singh, Kurt W. Fisher, Alexander T. Hewlett
Publikováno v:
Case Reports in Gastrointestinal Medicine, Vol 2018 (2018)
A 55-year-old woman presented with persistent nausea, vomiting, and weight loss previously attributed to Ménétrier’s disease. On further workup, she was found to have metastatic lobular breast carcinoma causing gastric outlet obstruction, diagnos
Externí odkaz:
https://doaj.org/article/c0ea828bf9734003b08cdc9242f10b6e
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 23:e125-e129
Autor:
Nicholas T. Woods, Michael A. Hollingsworth, Fang Yu, Kurt W. Fisher, Leah M. Cook, Paul M. Grandgenett, Dominick J. DiMaio, Jean L. Grem, Thomas C. Caffrey, Diane Costanzo-Garvey, Kimiko L. Krieger, Zachary S. Wagner, Fangfang Qiao, Emalie J. Clement, Dragana Lagundžin, Henry C.-H. Law
Purpose:Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease that can be separated into distinct subtypes based on molecular signatures. Identifying PDAC subtype-specific therapeutic vulnerabilities is necessary to develop precision
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18245fe79d990d12c750b74042382343
https://doi.org/10.1158/1078-0432.c.6528738
https://doi.org/10.1158/1078-0432.c.6528738
Autor:
Nicholas T. Woods, Michael A. Hollingsworth, Fang Yu, Kurt W. Fisher, Leah M. Cook, Paul M. Grandgenett, Dominick J. DiMaio, Jean L. Grem, Thomas C. Caffrey, Diane Costanzo-Garvey, Kimiko L. Krieger, Zachary S. Wagner, Fangfang Qiao, Emalie J. Clement, Dragana Lagundžin, Henry C.-H. Law
Figure S6: Protein expression and gene ontology analysis related to PDAC subtypes. Figure S7: The characterization of Protein Cluster 1. Figure S8: The characterization of Protein Cluster 2. Figure S9: The characterization of Protein Cluster 3. Figur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c4e36883853066f2ebb6d12db1554b
https://doi.org/10.1158/1078-0432.22474263.v1
https://doi.org/10.1158/1078-0432.22474263.v1
Autor:
Nicholas T. Woods, Michael A. Hollingsworth, Fang Yu, Kurt W. Fisher, Leah M. Cook, Paul M. Grandgenett, Dominick J. DiMaio, Jean L. Grem, Thomas C. Caffrey, Diane Costanzo-Garvey, Kimiko L. Krieger, Zachary S. Wagner, Fangfang Qiao, Emalie J. Clement, Dragana Lagundžin, Henry C.-H. Law
Table S1: The demographics of the patients involved in the study, classified by stage at diagnosis. Table S2: The TMT labelling scheme of all 8 batches of samples. Table S3: The total list of proteins identified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e527f073649c983cb5619180d5d470
https://doi.org/10.1158/1078-0432.22474254
https://doi.org/10.1158/1078-0432.22474254