Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Kurt W. Evans"'
Autor:
Turcin Saridogan, Argun Akcakanat, Ming Zhao, Kurt W. Evans, Erkan Yuca, Stephen Scott, Bryce P. Kirby, Xiaofeng Zheng, Min Jin Ha, Huiqin Chen, Patrick K. S. Ng, Timothy P. DiPeri, Gordon B. Mills, Jordi Rodon Ahnert, Senthil Damodaran, Funda Meric-Bernstam
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Several alterations in fibroblast growth factor receptor (FGFR) genes have been found in breast cancer; however, they have not been well characterized as therapeutic targets. Futibatinib (TAS-120; Taiho) is a novel, selective, pan-FGFR inhib
Externí odkaz:
https://doaj.org/article/54d8ba5ed19745f68237d1d74ca99a08
Autor:
Ming Zhao, Timothy P. DiPeri, Maria Gabriela Raso, Xiaofeng Zheng, Yasmeen Qamar Rizvi, Kurt W. Evans, Fei Yang, Argun Akcakanat, Marco Roberto Estecio, Debu Tripathy, Ecaterina E. Dumbrava, Senthil Damodaran, Funda Meric-Bernstam
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract TROP2 antibody drug conjugates (ADCs) are under active development. We seek to determine whether we can enhance activity of TROP2 ADCs by increasing TROP2 expression. In metaplastic breast cancers (MpBC), there is limited expression of TROP2
Externí odkaz:
https://doaj.org/article/153c2e942072429c8da59c33c6ea4273
Autor:
Seyed Pairawan, Argun Akcakanat, Scott Kopetz, Coya Tapia, Xiaofeng Zheng, Huiqin Chen, Min Jin Ha, Yasmeen Rizvi, Vijaykumar Holla, Jing Wang, Kurt W. Evans, Ming Zhao, Naifa Busaidy, Bingliang Fang, Jack A. Roth, Ecaterina Ileana Dumbrava, Funda Meric-Bernstam
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Most tumors with activating MAPK (mitogen-activated protein kinase) pathway alterations respond poorly to MEK inhibitors alone. Here, we evaluated combination therapy with MEK inhibitor selumetinib and MDM2 inhibitor KRT-232 in TP53 wild-typ
Externí odkaz:
https://doaj.org/article/51b40b75a51c478a93d56c2bf88693c8
Autor:
Rozita Bagheri-Yarmand, Naifa L. Busaidy, Elena McBeath, Brian P. Danysh, Kurt W. Evans, Tyler J. Moss, Argun Akcakanat, Patrick K. S. Ng, Christina M. Knippler, Jalyn A. Golden, Michelle D. Williams, Asha S. Multani, Maria E. Cabanillas, Kenna R. Shaw, Funda Meric-Bernstam, Manisha H. Shah, Matthew D. Ringel, Marie Claude Hofmann
Publikováno v:
Cancers, Vol 13, Iss 19, p 4950 (2021)
BRAF-activating mutations are the most frequent driver mutations in papillary thyroid cancer (PTC). Targeted inhibitors such as dabrafenib have been used in advanced BRAF-mutated PTC; however, acquired resistance to the drug is common and little is k
Externí odkaz:
https://doaj.org/article/9dc7cfc458d04b738ddeef3983415062
Autor:
Natalia Paez Arango, Erkan Yuca, Ming Zhao, Kurt W. Evans, Stephen Scott, Charissa Kim, Ana Maria Gonzalez-Angulo, Filip Janku, Naoto T. Ueno, Debu Tripathy, Argun Akcakanat, Aung Naing, Funda Meric-Bernstam
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-10 (2017)
Abstract Background Selinexor (KPT-330) is an oral agent that has been shown to inhibit the nuclear exporter XPO1. Given the pressing need for novel therapies for triple-negative breast cancer (TNBC), we sought to determine the antitumor effects of s
Externí odkaz:
https://doaj.org/article/aa1049178cee4907862f726c8c7667ec
Autor:
Funda Meric-Bernstam, Joseph R. Marszalek, Timothy P. Heffernan, Philip Jones, Giulio F. Draetta, Maria Emilia Di Francesco, Timothy A. Yap, Debu Tripathy, Bora Lim, Argun Akcakanat, Ken Chen, Coya Tapia, Xiaoping Su, Ana Maria Gonzalez-Angulo, Xiaofeng Zheng, Christopher P. Vellano, Christopher A. Bristow, Caleb A. Class, Maryam Shariati, Turcin Saridogan, Christian X. Cruz Pico, Natalia Paez Arango, Ming Zhao, Stephen S. Scott, Erkan Yuca, Kurt W. Evans
Table S1, Table S2, Table S3, Table S4, Figure S1 - S21, Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5def8ca555081d185395876e2b2ea8
https://doi.org/10.1158/0008-5472.22535180.v1
https://doi.org/10.1158/0008-5472.22535180.v1
Autor:
Funda Meric-Bernstam, Joseph R. Marszalek, Timothy P. Heffernan, Philip Jones, Giulio F. Draetta, Maria Emilia Di Francesco, Timothy A. Yap, Debu Tripathy, Bora Lim, Argun Akcakanat, Ken Chen, Coya Tapia, Xiaoping Su, Ana Maria Gonzalez-Angulo, Xiaofeng Zheng, Christopher P. Vellano, Christopher A. Bristow, Caleb A. Class, Maryam Shariati, Turcin Saridogan, Christian X. Cruz Pico, Natalia Paez Arango, Ming Zhao, Stephen S. Scott, Erkan Yuca, Kurt W. Evans
Oxidative phosphorylation (OXPHOS) is an active metabolic pathway in many cancers. RNA from pretreatment biopsies from patients with triple-negative breast cancer (TNBC) who received neoadjuvant chemotherapy demonstrated that the top canonical pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4de9512af0202eae249e70c5f911d8cd
https://doi.org/10.1158/0008-5472.c.6547778.v1
https://doi.org/10.1158/0008-5472.c.6547778.v1
Autor:
Funda Meric-Bernstam, Gordon B. Mills, Debu Tripathy, Timothy A. Yap, Jennifer K. Litton, Dalliah M. Black, Agda K. Eterovic, Emily Tarco, Coya Tapia, Ken Chen, Xiaofeng Zheng, Natalia Paez Arango, Stephen M. Scott, Argun Akcakanat, Erkan Yuca, Kurt W. Evans
HER2 FISH BCX.017
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f37d21beddd4ecb1cef5f145d78aaf
https://doi.org/10.1158/1078-0432.22469058
https://doi.org/10.1158/1078-0432.22469058
Autor:
Khandan Keyomarsi, Kelly K. Hunt, Funda Meric-Bernstam, Siqing Fu, Ian O. Ellis, Kwok-Leung Cheung, D. Christian Ellis, Min Yi, Kurt W. Evans, Smruthi Vijayaraghavan, Tuyen N. Bui, Jason P.W. Carey, Kenneth R. Hess, Cansu Karakas, Yufeng Jiang, Angela Alexander, Kwang-Huei Low, Xian Chen
supplementary figure 7-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4f3dbb50a1ca1da5b5986a20e0da0f
https://doi.org/10.1158/1078-0432.22469804
https://doi.org/10.1158/1078-0432.22469804
Autor:
Funda Meric-Bernstam, Gordon B. Mills, Debu Tripathy, Timothy A. Yap, Jennifer K. Litton, Dalliah M. Black, Agda K. Eterovic, Emily Tarco, Coya Tapia, Ken Chen, Xiaofeng Zheng, Natalia Paez Arango, Stephen M. Scott, Argun Akcakanat, Erkan Yuca, Kurt W. Evans
Correlations to TNBCtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3eb1b646a969546756f8668d6f6cd4
https://doi.org/10.1158/1078-0432.22469037
https://doi.org/10.1158/1078-0432.22469037