Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kurt Stahl"'
Autor:
Hua Li, Ezio Bonvini, Paul Moore, Francine Chen, Alexey Berezhnoy, Kalpana Shah, Daorong Liu, Peter Lung, Vatana Long, Kurt Stahl, Douglas Smith, Jonathan Li, Ralph Alderson, Valentina Ciccarone, James Tamura, Gundo Diedrich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/54b2afd02e014c6a86541895f622190c
Autor:
Kurt Stahl, Ralph Alderson, Kalpana Shah, Francine Chen, Valentina Ciccarone, Gundo Diedrich, Hua Li, Jonathan Yu-Meng Li, Vatana Long, Paul Moore, Daorong Liu, Douglas H. Smith, Alexey Berezhnoy, Ezio Bonvini, Peter Lung, James Tamura
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Interleukin-10 (IL-10) is a multifunctional cytokine that can mediate immune suppression or activation depending on the immunological context. Mouse studies have demonstrated that blockade of IL-10 enhances immune response against tumors a
Autor:
Kurt Stahl, Gregory M. Cote, Anushka De Costa, Kalpana Shah, Daorong Liu, Johanna C. Bendell, Sanjeev Kaul, Alexey Berezhnoy, Hua Li, Su-Shin Hao, Ezio Bonvini, Manish R. Sharma, Francine Chen, Jason J. Luke, Rachel E. Sanborn, Jonathan C. Li, Paul A. Moore, Bradley James Sumrow, Gundo Diedrich
Publikováno v:
Cell Reports Medicine
Summary Combination immunotherapy with antibodies directed against PD-1 and CTLA-4 shows improved clinical benefit across cancer indications compared to single agents, albeit with increased toxicity. Leveraging the observation that PD-1 and CTLA-4 ar
Autor:
Liqin Liu, Syd Johnson, Chia-Ying Kao Lam, Ralph Alderson, Thomas Kaufman, Hua Li, Sharad K. Sharma, Jennifer Brown, Paul Moore, Kurt Stahl, Ross La Motte-Mohs, James Tamura, Ezio Bonvini, Ling Huang
Publikováno v:
Blood. 132:5230-5230
Background: CD3-engaging DART molecules direct T cells to tumor-expressed antigens. Flotetuzumab, a CD123 x CD3 bispecific DART molecule that targets the differential expression of the IL-3 receptor alpha chain (CD123) on acute myeloid leukemia (AML)
Autor:
Kalpana Shah, Hua Li, Gurunadh Reddy Chichili, Sergey Gorlatov, Jennifer R. Brown, Valentina Ciccarone, Jim Tamura, Kurt Stahl, Leilei He, Ralph Alderson, Alex Berezhnoy, Christine Shoemaker, Paul A. Moore, Jessica Hill, Ross La Motte-Mohs, Daorong Liu, Jonathan Yu-Meng Li, Syd Johnson, Ezio Bonvini
Publikováno v:
Cancer Research. 77:3637-3637
Introduction: Immunotherapy with the combination of monoclonal antibodies (mAbs) that block PD-1 (nivolumab) and CTLA-4 (ipilimumab) has shown clinical benefit beyond that observed with either mAb alone. We have developed PD-1 x CTLA-4 bispecific pro
Publikováno v:
SAGE Open Medical Case Reports, Vol 10 (2022)
Congenital peritoneal encapsulation is a rare entity characterized by an accessory peritoneal membrane that forms during embryonic development. Congenital peritoneal encapsulation is generally asymptomatic but can cause intermittent, colicky abdomina
Externí odkaz:
https://doaj.org/article/546f50fbff244ca3bd9192f403d77843