Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kurt Scudder"'
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 8:499-512
Dissolution of organic compounds in DMSO in HTS plate or tube format is a difficult problem as users move to higher compression plate formats. Precipitation of compounds from DMSO screening stocks is a recognized problem in the HTS materials manageme
Publikováno v:
Analytical Chemistry. 65:3566-3570
A new flow cell design for spectroscopic measurements of suspensions, the jet ring cell, is introduced. This cell exploits radial flow through a narrow ring-shaped gap to retain suspended particles within the detection region. This ring constitutes a
Autor:
Kurt Scudder, Per Arkhammar, Morten Praestegaard, Morten Heide, Viggo Linde, Ivan Mikkelsen, Søren Møller, Frosty Loechel, Robert Terry, Betina Kerstin Lundholt, Søren Jensby Nielsen, Hans-Christian Pedersen, Sara Petersen Bjørn
Publikováno v:
Journal of biomolecular screening. 10(1)
The PI3-kinase/Akt pathway is an important cell survival pathway that is deregulated in the majority of human cancers. Despite the apparent druggability of several kinases in the pathway, no specific catalytic inhibitors have been reported in the lit
Publikováno v:
Cellular signalling. 16(8)
We report on a novel method to monitor changes in intracellular cAMP concentration ([cAMP] i ) within intact living cells using a chimeric fusion of the catalytic subunit of cAMP-dependent protein kinase to green fluorescent protein (PKAcat-GFP). In
Publikováno v:
Analytical chemistry. 64(21)
Publikováno v:
The Analyst. 121:945
Studying responses of live cells to agonists, antagonists and other physical stimuli offers insight into their complex membrane and internal biochemistry. An experimental technique has been developed in which responses of living cells in an inverted
Autor:
Betina Kerstin Lundholt, Viggo Linde, Frosty Loechel, Hans-Christian Pedersen, Sren Mller, Morten Prstegaard, Ivan Mikkelsen, Kurt Scudder, Sara Petersen Bjrn, Morten Heide, Per O. G. Arkhammar, Robert Terry, Sren Jensby Nielsen
Publikováno v:
Journal of Biomolecular Screening; Feb2005, Vol. 10 Issue 1, p20-29, 10p