Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kurt Schaudt"'
Autor:
Hilke Friccius, Elke Schlotz, David M. Sansom, Petra Siegels-Hübenthal, Heike Pohla, Kurt Schaudt, Graham Pawelec, Arnika Rehbein, Martina Boshell
Publikováno v:
Cellular Immunology. 162:8-15
A condition of hyporesponsiveness can be induced in certain mature human αβ (TCR2) cells relatively easily by their stimulation in the absence of costimulatory signals (signal 1 alone). This state of "anergy" has been implicated in tolerance to sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4715e9ed097fdfd556b0dec801a3ffbb
https://doi.org/10.1006/cimm.1995.1045
https://doi.org/10.1006/cimm.1995.1045
Autor:
Petra Siegels-Hübenthal, Kurt Schaudt, Medi Adibzadeh, Graham Pawelec, Hans-Jörg Bühring, Heike Pohla, Martin Owsianowsky, Arnika Rehbein, Andrea Schenk, Elke Schlotz, Thomas Deikeler
Publikováno v:
Developmental Immunology
In order to study extrathymic differentiationin vitro, CD7+CD3-lymphocytes were sorted from normal human bone marrow and cultured under conditions of limiting dilution together with irradiated pooled allogeneic peripheral blood mononuclear cells (PBM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdf27f0ff5a3237cb95e769aa79e365
http://europepmc.org/articles/PMC2275928
http://europepmc.org/articles/PMC2275928
Publikováno v:
Immunology Today. 16:420-422
Suboptimal function of an aged immune system may contribute significantly to morbidity and mortality in the elderly. At present, little is known of the biochemistry and molecular genetics of immunosenescence in humans. A recent meeting 1 1The 2nd Int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe231619868b53f9c59a63504da01251
https://doi.org/10.1016/0167-5699(95)80017-4
https://doi.org/10.1016/0167-5699(95)80017-4
Autor:
Arnika Rehbein, Heike Pohla, Kurt Schaudt, Elke Schlotz, Hilke Friccius, Graham Pawelec, Andreas Hambrecht
Publikováno v:
Cytokine. 7(4)
Although interleukin (IL)-10 inhibited lymphocyte proliferation in mixed lymphocyte cultures (MLC) and blocked stimulation of alloreactive T cell clones (TCC) by peripheral blood mononuclear cells (PBMC), the cells surviving culture with IL-10 showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6470995e62846ccd64aecb36017c69
https://pubmed.ncbi.nlm.nih.gov/8589266
https://pubmed.ncbi.nlm.nih.gov/8589266
Autor:
Medi Adibzadeh, Graham Pawelec, Elke Schlotz, Thomas Daikeler, Kurt Schaudt, Petra Siegels-Hübenthal, Arnika Rehbein, Heike Pohla, Bühring Hj, A. Schenk, M. Owsianowsky
Publikováno v:
Cellular immunology. 154(1)
To enrich low-density human bone marrow (BM) cells for putative progenitors of T-lymphocytes, CD7+ CD3- cells were sorted (purity was estimated at > 99.9%) and cultured under limiting dilution conditions with irradiated allogeneic stimulator cells, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857802d3f0e706b370178278dc0a75ed
https://pubmed.ncbi.nlm.nih.gov/8118889
https://pubmed.ncbi.nlm.nih.gov/8118889
Publikováno v:
International journal of immunopharmacology. 13(2-3)
Four antifungal agents have been screened in vitro for their immunosuppressive effects on proliferative responses in human mixed lymphocyte cultures (MLC). A hierarchy of inhibitory activity was observed, where itraconazole was greater than ketoconaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8ccce20578636f9d15174e3c74a405
https://pubmed.ncbi.nlm.nih.gov/1649144
https://pubmed.ncbi.nlm.nih.gov/1649144
Publikováno v:
Transplantation. 49(3)
The effects of exogenous cytokines on the generation of alloindifferent, MHC-unrestricted suppressive activity early on in mixed lymphocyte culture interactions have been investigated. Interleukin 4 strongly blocked the generation of suppression, whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa584dbd4b00146ae08fb203d88648f
https://pubmed.ncbi.nlm.nih.gov/1690473
https://pubmed.ncbi.nlm.nih.gov/1690473
Autor:
Bühring Hj, H.J. Lenz, G. Ehninger, E. Schneider, U. Schwuléra, G. Pawelec, Kurt Schaudt, H. Schlag
Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS ISBN: 9783540522812
Experience of the use of interleukin-2 (IL-2) to treat cancer patients has been almost exclusively based on trials with recombinant (nonglycosylated) lymphokine. Cell line (JURKAT)-derived IL-2 has been used clinically in a limited way, without drama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c69a4c3e45ff97cea8a37f42da0bb12
https://doi.org/10.1007/978-3-642-75510-1_94
https://doi.org/10.1007/978-3-642-75510-1_94
Publikováno v:
Transplantation. 51:917
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4a3cc6c4595d6aa0d356b120f976c0
https://doi.org/10.1097/00007890-199104000-00039
https://doi.org/10.1097/00007890-199104000-00039
Publikováno v:
European journal of immunology. 19(1)
Tumor necrosis factor-alpha (TNF-alpha) is a pleiotropic lymphokine which may have important regulatory effects on immune responses. It is shown here that eight alloreactive CD4+ T cell clones (TCC) secreted significant amounts of TNF-alpha after sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c910ed618cd36dbee8d0552adc28f4
https://pubmed.ncbi.nlm.nih.gov/2522047
https://pubmed.ncbi.nlm.nih.gov/2522047