Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kurt R.H. Repke"'
Autor:
Kurt R.H. Repke
Publikováno v:
Drug Discovery Today. 2:110-116
Increased incidence and prevalence of congestive heart failure make the discovery of novel positive inotropes (i.e. agents that increase the peak force of contraction of the heart muscle) a priority. Cardiac glycosides currently in use are inadequate
Publikováno v:
Journal of Chromatography A. 154:197-202
The paper probes 13 diol reagents known to interact with the cis -1,2,- and/or -1,3-diol groups of carbohydrates and other compounds, as to their influence on the relative mobilities of 16-acetylgitoxin and acetylgitoxin-α as representative for cis
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 770:183-194
The present study aimed to clarify the existence of a Na+/Ca2+ antiport device in kidney tubular epithelial cells discussed in the literature to represent the predominant mechanistic device for Ca2+ reabsorption in the kidney. (1) Inside-out oriented
Autor:
Kurt R.H. Repke, Werner Schönfeld
Publikováno v:
Trends in Pharmacological Sciences. 5:393-397
The cardiac glycosides are used extensively in the treatment of heart failure yet have a very low therapeutic index. It is generally believed that digitalis action on cardiac muscle is mediated via binding to a specific receptor site present on the m
Autor:
Frank Dittrich, Kurt R.H. Repke
Publikováno v:
Trends in Pharmacological Sciences. 1:398-402
Publikováno v:
Journal of Chromatography A. 155:169-177
On the influence of phenylboronic and diphenylborinic acid on the paper chromatographic mobilities of cardenolides and bufadienolides Phenylboronic acid and diphenylborinic acid were studied as to their influence on the paper chromatographic mobiliti
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 601:34-46
Spin-labelled ATP [3'-O-(1-oxyl-2,2,5,5-tetramethyl-3-carbonyl pyrrolidine)-adenosine 5'-triphosphate], abbreviated SL-ATP, is used to study firstly the occurrence of an associative phosphorane mechanism for the phosphoryl transfer from ATP to the tr
Publikováno v:
Journal of Labelled Compounds. 5:230-240
Cassaidin-7α-T und Cassaidinsaure-7α- T (spezifische Aktivitat jeweils 20 mC/mMol) werden dargestellt durch Reduktion der Ketogruppe an C-7 von Cassain mit Natriumborhydrid-T (spezifische Aktivitat 80 mC/mMol), gegebenenfalls gefolgt von saurer Hyd
Publikováno v:
Biochimica et biophysica acta. 550(3)
The controlling effect of ATP, K+ and Na+ on the rate of (Na+ + K+)-ATPase inactivation by 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole (NBD-C1) is used for the mathematical modelling of the interaction of the effectors with the enzyme under equilibrium c
Publikováno v:
Biochemical and biophysical research communications. 119(1)
Cibacron Blue F3GA (Cb) effectively and reversibly inhibits the activity of (Na,K)-ATPase. Its inhibitory effect does not occur through occupation of the ouabain binding site, but presumably results from Cb-occupation of one catalytic site not compet