Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Kurt R. Zinn"'
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract Introduction Nose‐to‐brain (N2B) insulin delivery has potential for Alzheimer's disease (AD) therapy. However, clinical implementation has been challenging without methods to follow N2B delivery non‐invasively. Positron emission tomogr
Externí odkaz:
https://doaj.org/article/758386ebb24e43f3a7ed219cbdce7b96
Autor:
Abdullah Metebi, Nathan Kauffman, Lu Xu, Satyendra Kumar Singh, Chelsea Nayback, Jinda Fan, Nathan Johnson, John Diemer, Terry Grimm, Mike Zamiara, Kurt R. Zinn
Publikováno v:
Frontiers in Chemistry, Vol 11 (2024)
Introduction: Better treatments for ovarian cancer are needed to eliminate residual peritoneal disease after initial debulking surgery. The present study evaluated Trastuzumab to deliver Pb-214/Bi-214 for targeted alpha therapy (TAT) for HER2-positiv
Externí odkaz:
https://doaj.org/article/9a1917e1381940c4b5301d4ad5ba6f68
Publikováno v:
Science and Technology of Advanced Materials, Vol 24, Iss 1 (2023)
ABSTRACTIn biomedical imaging, it is desirable that custom-made accessories for restraint, anesthesia, and monitoring can be easily cleaned and not interfere with the imaging quality or analyses. With the rise of 3D printing as a form of rapid protot
Externí odkaz:
https://doaj.org/article/dacfd5b7630448ca9043f698e837706c
Autor:
Chima V. Maduka, Mohammed Alhaj, Evran Ural, Oluwatosin M. Habeeb, Maxwell M. Kuhnert, Kylie Smith, Ashley V. Makela, Hunter Pope, Shoue Chen, Jeremy M. Hix, Christiane L. Mallett, Seock‐Jin Chung, Maxwell Hakun, Anthony Tundo, Kurt R. Zinn, Kurt D. Hankenson, Stuart B. Goodman, Ramani Narayan, Christopher H. Contag
Publikováno v:
Advanced Science, Vol 10, Iss 31, Pp n/a-n/a (2023)
Abstract Polylactide (PLA) is the most widely utilized biopolymer in medicine. However, chronic inflammation and excessive fibrosis resulting from its degradation remain significant obstacles to extended clinical use. Immune cell activation has been
Externí odkaz:
https://doaj.org/article/408418a830b44e06a5ab13ddc43a573a
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Intravascularly administered radiation therapy using beta (β-)-emitting radioisotopes has relied on either intravenously injected radiolabeled peptides that target cancer or radiolabeled microspheres that are trapped in the tumor following intra-art
Externí odkaz:
https://doaj.org/article/07066aaacbc340d9b7b433ff0297e14f
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1138 (2023)
A paradigm shift is underway in cancer diagnosis and therapy using radioactivity-based agents called radiopharmaceuticals. In the new strategy, diagnostic imaging measures the tumor uptake of radioactive agent “X” in a patient’s specific cancer
Externí odkaz:
https://doaj.org/article/28ba350ce5f94308b636b3f1bf9ace7b
Autor:
Kairong Li, Ashley N. Turner, Min Chen, Stephanie N. Brosius, Trenton R. Schoeb, Ludwine M. Messiaen, David M. Bedwell, Kurt R. Zinn, Corina Anastasaki, David H. Gutmann, Bruce R. Korf, Robert A. Kesterson
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 7, Pp 759-767 (2016)
Neurofibromatosis type 1 (NF1) is a common genetic disorder characterized by the occurrence of nerve sheath tumors and considerable clinical heterogeneity. Some translational studies have been limited by the lack of animal models available for assess
Externí odkaz:
https://doaj.org/article/0316d1cb159646e299039a5e2abac96f
Autor:
Hyunki Kim, Karri D. Folks, Lingling Guo, Jeffery C. Sellers, Naomi S. Fineberg, Cecil R. Stockard, William E. Grizzle, Donald J. Buchsbaum, Desiree E. Morgan, James F. George, Kurt R. Zinn
Publikováno v:
Molecular Imaging, Vol 10 (2011)
Early pancreatic cancer response following cetuximab and/or irinotecan therapies was measured by serial dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) before and during therapy. Groups 1 to 4 ( n = 6/group) of SCID mice bearing orthot
Externí odkaz:
https://doaj.org/article/a1eb7222d69b43a3aaa0faae80ea31c1
Autor:
Anton V. Borovjagin, Lacey R. McNally, Minghui Wang, David T. Curiel, Mary J. MacDougall, Kurt R. Zinn
Publikováno v:
Molecular Imaging, Vol 9 (2010)
Genetic capsid labeling of conditionally replicative adenoviruses (CRAds) with fluorescent tags offers a potentially more accurate monitoring of those virotherapy agents in vivo. The capsid of an infectivity-enhanced CRAd, Ad5/3, delta 24, was geneti
Externí odkaz:
https://doaj.org/article/d68600564ca843b080415f4477bfea04
Autor:
Kristopher J. Kimball, Angel A. Rivera, Kurt R. Zinn, Mert Icyuz, Vaibhav Saini, Jing Li, Zeng B. Zhu, Gene P. Siegal, Joanne T. Douglas, David T. Curiel, Ronald D. Alvarez, Anton V. Borovjagin
Publikováno v:
Molecular Imaging, Vol 8 (2009)
We sought to develop a cancer-targeted, infectivity-enhanced oncolytic adenovirus that embodies a capsid-labeling fusion for non-invasive dual-modality imaging of ovarian cancer virotherapy. A functional fusion protein composed of fluorescent and nuc
Externí odkaz:
https://doaj.org/article/80e945348aad45c5b929bba0299c9446