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Autor:
Sophia G. Robinson, JoAnn K. Girel, Karla Arias, Matt Hartzell, Stephanie S. Lyngaas, Kurt Liechti, Sanjay S. Cherala, Lihua Jin, Stacey Mei, Andreas Kuemmell, Azra Vilic, Joseph Lawrence Zielinski, John S. Vrettos
Publikováno v:
Inorganica Chimica Acta. 441:181-191
Tetracycline (TC), minocycline (MIN) and tigecycline (TIG) share a divalent metal ion binding site essential for mediating their antibiotic function. Isothermal titration calorimetry (ITC) and UV–Vis absorbance measurements combined with the Job’