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pro vyhledávání: '"Kurt J. Mynett"'
Autor:
Allen P. Yates, Rhoderick H Elder, Kurt J. Mynett, Geoffrey P. Margison, John Cardinal, Donald P. Cameron
Publikováno v:
Molecular and Cellular Biology. 21:5605-5613
Type 1 diabetes is thought to occur as a result of the loss of insulin-producing pancreatic beta cells by an environmentally triggered autoimmune reaction. In rodent models of diabetes, streptozotocin (STZ), a genotoxic methylating agent that is targ
Autor:
Rhoderick H Elder, Kurt J. Mynett, Susan W.P. Wijnhoven, Mark Andrew Willington, John A. Bailey, Bryan Deans, Albert A. van Zeeland, Mel C. Heeran, Jacob G. Jansen, Donald P. Cooper, Amanda J. Watson, Joseph A Rafferty, Robert J. Weeks, Geoffrey P. Margison
Publikováno v:
Molecular and cellular biology. 18(10)
Alkylpurine-DNA-N-glycosylase (APNG) null mice have been generated by homologous recombination in embryonic stem cells. The null status of the animals was confirmed at the mRNA level by reverse transcription-PCR and by the inability of cell extracts