Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kurt Altman"'
Publikováno v:
Endocrinology. 94:325-329
In vitro incubation of 7α-3H-testosterone with crushed mandibular bone of castrated male rats shows that the steroid is converted to both androgenic and estrogenicmetabolites. The metabolism to androgens is characterized by formation of Sa-and 5β-r
Publikováno v:
Journal of Dental Research. 57:511-519
Rat oral mucosa microsomal Δ 4-3-ketosteroid-5α-A-ring reductase enzyme system, reducing testosterone and 4-androstenedione, was found to be inducible by systemic administration of medroxyprogesterone acetate (MPA). MPA, when used in a mixture with
Publikováno v:
Journal of Autoimmunity. 2:833-842
In vivo immune clearance of immunoglobulin G sensitized autologous erythrocytes (rbc) was studied in nine patients who fulfilled American Rheumatism Association (ARA) criteria for systemic lupus erythematosus (SLE). Opsonized rbc were radiolabelled w
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 30:449-456
Oral administration of medroxyprogesterone acetate to 4 normal male and 3 normal female subjects was found to produce a significant increase in the metabolic clearance rate of testosterone in 6 of the 7 subjects. The plasma levels and production rate
Autor:
Mark S. Tobin, Kurt Altman
Publikováno v:
Experimental Biology and Medicine. 115:225-228
SummaryRabbits treated with D-L penicillamine for 28 days prior to intravenous injection of I131 labeled human serum albumin showed accelerated elimination of the antigen and correspondingly earlier appearance of free antibody, as compared with contr
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 32:457-461
Testosterone A-ring reductase activity was measured in human liver obtained from 6 normal volunteers by aspiration liver biopsy. The base line enzyme activity varied between 62 and 132 nmoles of testosterone metabolized per hr per mg liver protein. A
Publikováno v:
Proceedings of the National Academy of Sciences. 69:3567-3569
Within 3 hr after the intraperitoneal administration of hydrocortisone to female rats, a new leucine-accepting tRNA and a new leucyl-tRNA synthetase activity appear in the liver cytosol. The new isoaccepting tRNA can be acylated only with the synthet
Publikováno v:
Science (New York, N.Y.). 191(4227)
Male alcoholics often suffer from features of hypogonadism related to abnormal metabolism of sex steroids. Since the activity of testosterone reductases is rate limiting for testosterone metabolism in the liver, the effect of prolonged ethanol consum
Publikováno v:
The New England journal of medicine. 295(15)
To determine whether ethanol per se affects testosterone metabolism, alcohol was administered to normal male volunteers for periods up to four weeks, resulting in an initial dampening of the episodic bursts of testosterone secretion followed by decre