Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Kurt A. Johnson"'
Autor:
Xu Zhang, Vesselina M. Pearsall, Chase M. Carver, Elizabeth J. Atkinson, Benjamin D. S. Clarkson, Ethan M. Grund, Michelle Baez-Faria, Kevin D. Pavelko, Jennifer M. Kachergus, Thomas A. White, Renee K. Johnson, Courtney S. Malo, Alan M. Gonzalez-Suarez, Katayoun Ayasoufi, Kurt O. Johnson, Zachariah P. Tritz, Cori E. Fain, Roman H. Khadka, Mikolaj Ogrodnik, Diana Jurk, Yi Zhu, Tamara Tchkonia, Alexander Revzin, James L. Kirkland, Aaron J. Johnson, Charles L. Howe, E. Aubrey Thompson, Nathan K. LeBrasseur, Marissa J. Schafer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The authors discovered that proinflammatory senescent myeloid cells may recruit peripheral immune cells in the aged mouse brain. Their findings implicate senescent cell clearance as a strategy to counter aged brain inflammation and cognitive decline.
Externí odkaz:
https://doaj.org/article/563782268a174f9491ef229d9fd5e5e9
Publikováno v:
Human Immunology. 84:286-289
Autor:
Allen W. Heinemann, Kurt L. Johnson, Pamela Palmentera, Miriam R. Rafferty, Laura Stoff, Pamela Capraro, Ivorie Stanley
Publikováno v:
Journal of Occupational Rehabilitation. 31:275-284
Purpose People with Parkinson’s disease (PwP) exit the workforce on average 5 years earlier than people without Parkinson’s due to motor, cognitive, communicative, and affective symptoms. Decreased employment results in significant individual and
Publikováno v:
Patient Related Outcome Measures, Vol 2010, Iss default, Pp 65-71 (2010)
Karon F Cook1, Seung W Choi2, Kurt L Johnson1, Dagmar Amtmann11Department of Rehabilitation Medicine, University of Washington, Seattle, WA; 2Northwestern University Feinberg School of Medicine, Chicago, IL, USAAbstract: There are clinical and resear
Externí odkaz:
https://doaj.org/article/dff500633b694341902635af2ccc7087
Publikováno v:
Clinical Epidemiology, Vol 2010, Iss default, Pp 99-106 (2010)
Alyssa M Bamer, Kurt L Johnson, Dagmar A Amtmann, George H KraftDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, USABackground: Recent research indicates that sleep disturbances are common in persons with multiple scleros
Externí odkaz:
https://doaj.org/article/718050909fb044e291c59bb1d7031af4
Autor:
Ming Xu, Allyson K Palmer, Husheng Ding, Megan M Weivoda, Tamar Pirtskhalava, Thomas A White, Anna Sepe, Kurt O Johnson, Michael B Stout, Nino Giorgadze, Michael D Jensen, Nathan K LeBrasseur, Tamar Tchkonia, James L Kirkland
Publikováno v:
eLife, Vol 4 (2015)
Senescent cells accumulate in fat with aging. We previously found genetic clearance of senescent cells from progeroid INK-ATTAC mice prevents lipodystrophy. Here we show that primary human senescent fat progenitors secrete activin A and directly inhi
Externí odkaz:
https://doaj.org/article/ec852c46c83c4207854436df1e2e57e8
Autor:
Xu Zhang, Vesselina M. Pearsall, Chase M. Carver, Elizabeth J. Atkinson, Benjamin D. S. Clarkson, Ethan M. Grund, Michelle Baez-Faria, Kevin D. Pavelko, Jennifer M. Kachergus, Thomas A. White, Renee K. Johnson, Courtney S. Malo, Alan M. Gonzalez-Suarez, Katayoun Ayasoufi, Kurt O. Johnson, Zachariah P. Tritz, Cori E. Fain, Roman H. Khadka, Mikolaj Ogrodnik, Diana Jurk, Yi Zhu, Tamara Tchkonia, Alexander Revzin, James L. Kirkland, Aaron J. Johnson, Charles L. Howe, E. Aubrey Thompson, Nathan K. LeBrasseur, Marissa J. Schafer
Publikováno v:
Nature communications. 13(1)
Cellular senescence is a plausible mediator of inflammation-related tissue dysfunction. In the aged brain, senescent cell identities and the mechanisms by which they exert adverse influence are unclear. Here we used high-dimensional molecular profili
Autor:
Kurt L. Johnson, Mark Harniss
Publikováno v:
Manual of Traumatic Brain Injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae20fc1056c7d7229bafba632b6754cf
https://doi.org/10.1891/9780826147684.0039
https://doi.org/10.1891/9780826147684.0039
Autor:
Utkarsh Tripathi, Mark Pierson, Paul D. Robbins, Nino Giorgadze, James L. Kirkland, David B. Allison, Tamara Tchkonia, Stephen C. Jameson, Sara E. Hamilton, Larissa G.P. Langhi Prata, Christina L. Inman, Stephanie H. Cholensky, Lei Zhang, Elizabeth J. Atkinson, Ming Li, Yi Zhu, Christina D. Camell, Jair Machado Espindola-Netto, Laura J. Niedernhofer, Tamar Pirtskhalava, Matthew A. Huggins, Alexander Meves, Matthew J. Yousefzadeh, Sundeep Khosla, Keisuke Ejima, Sergio E. Chiarella, Y. S. Prakash, M. Gerard O'Sullivan, Ryan D. O’Kelly, Nathan K. LeBrasseur, Timothy W. Carlson, Pengcheng Xun, Kurt O. Johnson, Ailing Xue
Publikováno v:
Science (New York, N.Y.)
INTRODUCTION: The COVID-19 pandemic revealed enhanced vulnerability of the elderly and chronically ill to adverse outcomes upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Senescence is a cell fate elicited by cellular str
Autor:
Yi Zhu, João F. Passos, Kurt O. Johnson, Marissa J. Schafer, Diana Jurk, Edward Fielder, Christine Inman, Bettina M. Weigand, James L. Kirkland, Mikolaj Ogrodnik, Tamar Pirtskhalava, Shane A. Evans, Nicola Neretti, Ayush D. Patel, Thomas von Zglinicki, David B. Allison, Hanna Salmonowicz, Stella Victorelli, Nathan K. LeBrasseur, Tamar Tchkonia, Patrick Krüger, Azucena Rocha, Stephanie L. Dickinson
Publikováno v:
Aging Cell
Cellular senescence is characterized by an irreversible cell cycle arrest and a pro‐inflammatory senescence‐associated secretory phenotype (SASP), which is a major contributor to aging and age‐related diseases. Clearance of senescent cells has