Zobrazeno 1 - 10
of 371
pro vyhledávání: '"Kurt, Zatloukal"'
Autor:
Eleni M. Loizidou, Maria Kyratzi, Maria A. Tsiarli, Andrea C. Kakouri, Georgia Charalambidou, Stella Antoniou, Stylianos Pieri, Panagiota Veloudi, Michaela Th. Mayrhofer, Andrea Wutte, Lukasz Kozera, Jens Habermann, Heimo Muller, Kurt Zatloukal, Karine Sargsyan, Alexandros Michaelides, Maria Papaioannou, Christos Schizas, Apostolos Malatras, Gregory Papagregoriou, Constantinos Deltas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The Cyprus Biobank collects biosamples, medical and lifestyle information with the aim of reaching 16,500 Cypriots aged ≥ 18-years, by year 2027, as part of a multitasked EU funded project. Volunteers are both from the general population a
Externí odkaz:
https://doaj.org/article/e5470b8ee75847978735edb46beac09c
Autor:
Nic G. Reitsam, Bianca Grosser, David F. Steiner, Veselin Grozdanov, Ellery Wulczyn, Vincenzo L’Imperio, Markus Plass, Heimo Müller, Kurt Zatloukal, Hannah S. Muti, Jakob N. Kather, Bruno Märkl
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background Tumor-Adipose-Feature (TAF) as well as SARIFA (Stroma AReactive Invasion Front Areas) are two histologic features/biomarkers linking tumor-associated adipocytes to poor outcomes in colorectal cancer (CRC) patients. Whereas TAF was
Externí odkaz:
https://doaj.org/article/b0fe529a371d4beb95642cb9bd704ab1
Autor:
Julia Höhn, Eva Krieghoff-Henning, Christoph Wies, Lennard Kiehl, Martin J. Hetz, Tabea-Clara Bucher, Jitendra Jonnagaddala, Kurt Zatloukal, Heimo Müller, Markus Plass, Emilian Jungwirth, Timo Gaiser, Matthias Steeg, Tim Holland-Letz, Hermann Brenner, Michael Hoffmeister, Titus J. Brinker
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-12 (2023)
Abstract Studies have shown that colorectal cancer prognosis can be predicted by deep learning-based analysis of histological tissue sections of the primary tumor. So far, this has been achieved using a binary prediction. Survival curves might contai
Externí odkaz:
https://doaj.org/article/e094c1a7b01c4b7bb8979efab082563b
Autor:
Petr Holub, Heimo Müller, Tomáš Bíl, Luca Pireddu, Markus Plass, Fabian Prasser, Irene Schlünder, Kurt Zatloukal, Rudolf Nenutil, Tomáš Brázdil
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Access to large volumes of so-called whole-slide images—high-resolution scans of complete pathological slides—has become a cornerstone of the development of novel artificial intelligence methods in pathology for diagnostic use, education
Externí odkaz:
https://doaj.org/article/9c9ee166c04045f5a114176b5087ddd5
Autor:
Rudolf Wittner, Petr Holub, Cecilia Mascia, Francesca Frexia, Heimo Müller, Markus Plass, Clare Allocca, Fay Betsou, Tony Burdett, Ibon Cancio, Adriane Chapman, Martin Chapman, Mélanie Courtot, Vasa Curcin, Johann Eder, Mark Elliot, Katrina Exter, Carole Goble, Martin Golebiewski, Bron Kisler, Andreas Kremer, Simone Leo, Sheng Lin‐Gibson, Anna Marsano, Marco Mattavelli, Josh Moore, Hiroki Nakae, Isabelle Perseil, Ayat Salman, James Sluka, Stian Soiland‐Reyes, Caterina Strambio‐De‐Castillia, Michael Sussman, Jason R. Swedlow, Kurt Zatloukal, Jörg Geiger
Publikováno v:
Learning Health Systems, Vol 8, Iss 1, Pp n/a-n/a (2024)
Abstract Open and practical exchange, dissemination, and reuse of specimens and data have become a fundamental requirement for life sciences research. The quality of the data obtained and thus the findings and knowledge derived is thus significantly
Externí odkaz:
https://doaj.org/article/b93ad8533a86445b9fd50163b1ed76f6
Autor:
Justin D. Krogue, Shekoofeh Azizi, Fraser Tan, Isabelle Flament-Auvigne, Trissia Brown, Markus Plass, Robert Reihs, Heimo Müller, Kurt Zatloukal, Pema Richeson, Greg S. Corrado, Lily H. Peng, Craig H. Mermel, Yun Liu, Po-Hsuan Cameron Chen, Saurabh Gombar, Thomas Montine, Jeanne Shen, David F. Steiner, Ellery Wulczyn
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-9 (2023)
Abstract Background Presence of lymph node metastasis (LNM) influences prognosis and clinical decision-making in colorectal cancer. However, detection of LNM is variable and depends on a number of external factors. Deep learning has shown success in
Externí odkaz:
https://doaj.org/article/05e3699f48ec4fbbbf46c7ae3d19fa89
Autor:
Hui Qian, Xiaojuan Chao, Shaogui Wang, Yuan Li, Xiaoxiao Jiang, Zhaoli Sun, Thomas Rülicke, Kurt Zatloukal, Hong-Min Ni, Wen-Xing Ding
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 5, Pp 1027-1049 (2023)
Background: Alcohol-associated liver disease (ALD) is a worldwide health problem, of which the effective treatment is still lacking. Both detrimental and protective roles of adipose tissue have been implicated in ALD. Although alcohol increases adipo
Externí odkaz:
https://doaj.org/article/5da95cf1d2e54448a0f201e209fe9f08
Autor:
Katharina Köchl, Tobias Schopper, Vedat Durmaz, Lena Parigger, Amit Singh, Andreas Krassnigg, Marco Cespugli, Wei Wu, Xiaoli Yang, Yanchong Zhang, Welson Wen-Shang Wang, Crystal Selluski, Tiehan Zhao, Xin Zhang, Caihong Bai, Leon Lin, Yuxiang Hu, Zhiwei Xie, Zaihui Zhang, Jun Yan, Kurt Zatloukal, Karl Gruber, Georg Steinkellner, Christian C. Gruber
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Treatment of COVID-19 with a soluble version of ACE2 that binds to SARS-CoV-2 virions before they enter host cells is a promising approach, however it needs to be optimized and adapted to emerging viral variants. The computational workflow p
Externí odkaz:
https://doaj.org/article/09584ce721704992ad8d2da8bc68bc58
Autor:
Somanath Kallolimath, Roman Palt, Esther Föderl-Höbenreich, Lin Sun, Qiang Chen, Florian Pruckner, Lukas Eidenberger, Richard Strasser, Kurt Zatloukal, Herta Steinkellner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immunoglobulin M (IgM) is the largest antibody isotype with unique features like extensive glycosylation and oligomerization. Major hurdles in characterizing its properties are difficulties in the production of well-defined multimers. Here we report
Externí odkaz:
https://doaj.org/article/bcf70f19ab6f46cdba5a20edadf0c5d4
Autor:
Shiva Izadi, Ulrike Vavra, Stanislav Melnik, Clemens Grünwald-Gruber, Esther Föderl-Höbenreich, Markus Sack, Kurt Zatloukal, Josef Glössl, Eva Stöger, Lukas Mach, Alexandra Castilho, Richard Strasser
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
SARS-CoV-2 infects human cells via binding of the viral spike glycoprotein to its main cellular receptor, angiotensin-converting enzyme 2 (ACE2). The spike protein-ACE2 receptor interaction is therefore a major target for the development of therapeut
Externí odkaz:
https://doaj.org/article/b00aae2617684bc2bb46c3d926f815b9