Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Kurt, Vermeire"'
Autor:
Marijke Verhaegen, Kurt Vermeire
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-17 (2024)
Abstract Dengue virus (DENV) is the most prevalent arthropod-borne flavivirus and imposes a significant healthcare threat worldwide. At present no FDA-approved specific antiviral treatment is available, and the safety of a vaccine against DENV is sti
Externí odkaz:
https://doaj.org/article/8fc1494ddf5e41508b424e868fe54565
Autor:
Jan Van Slambrouck, Mona Khan, Erik Verbeken, Sumin Choi, Vincent Geudens, Cedric Vanluyten, Simon Feys, Emiel Vanhulle, Elke Wollants, Kurt Vermeire, Charlotte De Fays, Lucia Aversa, Janne Kaes, Dirk Van Raemdonck, Robin Vos, Bart Vanaudenaerde, Gert De Hertogh, Els Wauters, Joost Wauters, Laurens J. Ceulemans, Peter Mombaerts
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104608- (2023)
Summary: Background: SARS-CoV-2 is a single-stranded positive-sense RNA virus. Several negative-sense SARS-CoV-2 RNA species, both full-length genomic and subgenomic, are produced transiently during viral replication. Methodologies for rigorously cha
Externí odkaz:
https://doaj.org/article/c85f4c4df7ae425baf4fafbe7ce363ec
Publikováno v:
BioTechniques, Vol 72, Iss 6, Pp 245-254 (2022)
Basic and antiviral research on SARS-CoV-2 rely on cellular assays of virus replication in vitro. In addition, accurate detection of virus-infected cells and released virus particles is needed to study virus replication and to profile new candidate a
Externí odkaz:
https://doaj.org/article/d818019b274b4772a5986da5d93e90ca
Autor:
Belén Martinez-Gualda, Mirthe Graus, Anita Camps, Emiel Vanhulle, Sirle Saul, Siavash Azari, Do Hoang Nhu Tran, Laura Vangeel, Winston Chiu, Johan Neyts, Dominique Schols, Shirit Einav, Kurt Vermeire, Steven De Jonghe
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
RNA viral infections, including those caused by respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and Venezuelan Equine encephalitis virus (VEEV), pose a major global health challenge. Here, we report th
Externí odkaz:
https://doaj.org/article/b71621893a6241afbd7e65cfc4b5b2f3
Autor:
Emiel Vanhulle, Thomas D’huys, Becky Provinciael, Joren Stroobants, Anita Camps, Sam Noppen, Dominique Schols, Els J. M. Van Damme, Piet Maes, Annelies Stevaert, Kurt Vermeire
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Urtica dioica agglutinin (UDA) is a carbohydrate-binding small monomeric protein isolated from stinging nettle rhizomes. It inhibits replication of a broad range of viruses, including coronaviruses, in multiple cell types, with appealing selectivity.
Externí odkaz:
https://doaj.org/article/b8bea83cab5e4494bd4d230d23e683a9
Autor:
Birger Tielemans, Lander De Herdt, Emilie Pollenus, Emiel Vanhulle, Laura Seldeslachts, Fopke Marain, Flore Belmans, Kaveh Ahookhosh, Jeroen Vanoirbeek, Kurt Vermeire, Philippe E. Van den Steen, Greetje Vande Velde
Publikováno v:
Viruses, Vol 15, Iss 4, p 993 (2023)
Individuals with Down syndrome (DS) are more prone to develop severe respiratory tract infections. Although a RSV infection has a high clinical impact and severe outcome in individuals with DS, no vaccine nor effective therapeutics are available. Any
Externí odkaz:
https://doaj.org/article/1995685f9dc7468fba56ddeb73c0012e
Autor:
Elisa Claeys, Eva Pauwels, Stephanie Humblet-Baron, Becky Provinciael, Dominique Schols, Mark Waer, Ben Sprangers, Kurt Vermeire
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The small molecule cyclotriazadisulfonamide (CADA) down-modulates the human CD4 receptor, an important factor in T cell activation. Here, we addressed the immunosuppressive potential of CADA using different activation models. CADA inhibited lymphocyt
Externí odkaz:
https://doaj.org/article/4e52bcb39c314f059ca28d159532c3dd
Autor:
Bram Vrancken, Tony Wawina-Bokalanga, Bert Vanmechelen, Joan Martí-Carreras, Miles W Carroll, Justus Nsio, Jimmy Kapetshi, Sheila Makiala-Mandanda, Jean-Jacques Muyembe-Tamfum, Guy Baele, Kurt Vermeire, Valentijn Vergote, Steve Ahuka-Mundeke, Piet Maes
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0008117 (2020)
Ebolaviruses pose a substantial threat to wildlife populations and to public health in Africa. Evolutionary analyses of virus genome sequences can contribute significantly to elucidate the origin of new outbreaks, which can help guide surveillance ef
Externí odkaz:
https://doaj.org/article/ae228f0095a9452aa63eb3c0abeaeb01
Autor:
Jan Van Slambrouck, Mona Khan, Erik Verbeken, Sumin Choi, Vincent Geudens, Cedric Vanluyten, Simon Feys, Emiel Vanhulle, Elke Wollants, Kurt Vermeire, Charlotte De Fays, Lucia Aversa, Janne Kaes, Dirk Van Raemdonck, Robin Vos, Bart Vanaudenaerde, Gert De Hertogh, Els Wauters, Joost Wauters, Laurens J. Ceulemans, Peter Mombaerts
Background SARS-CoV-2 is a single-stranded positive-sense RNA virus. Several negative-sense SARS-CoV-2 RNA species, both full-length genomic and subgenomic, are produced transiently during viral replication. Methodologies for rigorously characterisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2229c168a0cdbd827389c3ca031b5fcd
https://lirias.kuleuven.be/handle/20.500.12942/719912
https://lirias.kuleuven.be/handle/20.500.12942/719912
Publikováno v:
Journal of Heterocyclic Chemistry. 59:1604-1615