Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kurt, Nikander"'
Publikováno v:
Journal of Dental Sleep Medicine. 8
Publikováno v:
Expert Opinion on Drug Delivery. 14:621-630
The mouth, the pharynx and the larynx are potential sites of aerosol deposition in the upper airway during inhalation of aerosolized drugs. The right angle bend of the lumen at the back of the mouth, the position of the tongue, the variable size and
Autor:
Kirby Tong Minh, Dirk von Hollen, Annemieke J. von Königslöw, Kurt Nikander, Hettie M. Janssens
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery, 27, S55-S62. Mary Ann Liebert Inc.
Pressurized metered dose inhalers (pMDIs), combined with a valved holding chamber (VHC) and facemask, are often used for young asthmatic children. When using a VHC with facemask, a tight seal between the facemask and the patient's face is crucial for
Autor:
Kurt Nikander
Publikováno v:
Expert Opinion on Drug Delivery. 7:1235-1238
Recent reviews conclude that there is a need to improve the management of respiratory diseases treated with inhaled drugs, mainly asthma and chronic obstructive pulmonary disease (COPD). Healthcare professionals - mainly in primary care - seem to lac
Autor:
John Pritchard, Mark Elphick, Dirk von Hollen, Ross Hatley, Lucy E. A. Hardaker, Kurt Nikander
Publikováno v:
Expert opinion on drug delivery. 12(8)
Nebulizers are a common device choice for use when developing a new drug product, but the range of nebulizer devices available can make it difficult to select the right device. Increasingly, companies are only able to promote a drug with the device t
Publikováno v:
Expert Opinion on Drug Delivery. 1:165-176
Jet nebulisers have, since the 1920s, been used for delivery of inhaled drugs for the treatment of asthma, chronic-obstructive pulmonary disease and pulmonary infections. During the last two decades, recognition of the shortcomings of conventional ne
Publikováno v:
Annals of Allergy, Asthma & Immunology. 90:226-232
Background Budesonide is an inhaled corticosteroid widely used in the treatment of asthma. The local and systemic availability of budesonide has been determined in adults via pressurized metered-dose inhaler and dry-powder inhaler. Objectives To esti
Publikováno v:
Thorax. 67:100-102
The clinical efficacy of inhaled corticosteroids (ICSs) in asthma has been demonstrated in long-term intervention studies,1 2 and ICSs are recommended first-line treatment of persistent asthma, even in children.3 The long-term benefits of early inter
Autor:
Dirk von Hollen, Christina Roller, Kurt Nikander, Sunalene G. Devadason, William Ditcham, Guicheng Zhang, Jasminka Murdzoska
Publikováno v:
Journal of aerosol medicine and pulmonary drug delivery. 27
Research on the use of a pressurized metered dose inhaler (pMDI) with spacer (pMDI/spacer) in children has indicated oral inhalation via the spacer mouthpiece is more efficient than the combination of oral and nasal inhalation that occurs when a pMDI
Publikováno v:
Journal of Aerosol Medicine. 13:139-146
The use of breathing simulators for the in vitro determination of the inhaled mass of drug from nebulizers has become widely accepted. Their use is, however, based on the assumption that there is a correlation between the in vitro and in vivo inhaled