Zobrazeno 1 - 10
of 524
pro vyhledávání: '"Kurppa P"'
Autor:
Majid Momeny, Mari Tienhaara, Mukund Sharma, Deepankar Chakroborty, Roosa Varjus, Iina Takala, Joni Merisaari, Artur Padzik, Andreas Vogt, Ilkka Paatero, Klaus Elenius, Teemu D Laajala, Kari J Kurppa, Jukka Westermarck
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1603-1629 (2024)
Abstract Despite clinical benefits of tyrosine kinase inhibitors (TKIs) in cancer, most tumors can reactivate proliferation under TKI therapy. Here we present transcriptional profiling of HER2+ breast cancer cells transitioning from dormant drug tole
Externí odkaz:
https://doaj.org/article/709f9a596c0c46e4951cbcebf8781895
Autor:
Jan Mueller, Roman R Schimmer, Christian Koch, Florin Schneiter, Jonas Fullin, Veronika Lysenko, Christian Pellegrino, Nancy Klemm, Norman Russkamp, Renier Myburgh, Laura Volta, Alexandre PA Theocharides, Kari J Kurppa, Benjamin L Ebert, Timm Schroeder, Markus G Manz, Steffen Boettcher
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 445-474 (2024)
Abstract TP53-mutant acute myeloid leukemia (AML) and myelodysplastic neoplasms (MDS) are characterized by chemotherapy resistance and represent an unmet clinical need. Chimeric antigen receptor (CAR) T-cells might be a promising therapeutic option f
Externí odkaz:
https://doaj.org/article/3995291a6c424aeaadea031a81b64f56
Autor:
Iida Ahonen, Pilvi Laurikka, Sara Koskimaa, Heini Huhtala, Katri Lindfors, Katri Kaukinen, Kalle Kurppa, Laura Kivelä
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Vomiting and nausea seem to be relatively specific symptoms related to gluten ingestion in treated celiac disease. However, the overall prevalence and associated factors of these symptoms after chronic gluten exposure at celiac di
Externí odkaz:
https://doaj.org/article/94269f493fe549e5aacea47e07924360
Publikováno v:
Atmospheric Chemistry and Physics, Vol 23, Pp 9347-9364 (2023)
Large-eddy simulation (LES) is an optimal tool to examine aerosol particle concentrations in detail within urban neighbourhoods. The concentrations are a complex result of local emissions, meteorology, aerosol processes and local mixing conditions du
Externí odkaz:
https://doaj.org/article/d836bca40b1044c39ef6d89df426aa8c
Akademický článek
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Autor:
C. Yan, Y. Shen, D. Stolzenburg, L. Dada, X. Qi, S. Hakala, A.-M. Sundström, Y. Guo, A. Lipponen, T. V. Kokkonen, J. Kontkanen, R. Cai, J. Cai, T. Chan, L. Chen, B. Chu, C. Deng, W. Du, X. Fan, X.-C. He, J. Kangasluoma, J. Kujansuu, M. Kurppa, C. Li, Y. Li, Z. Lin, Y. Liu, Y. Lu, W. Nie, J. Pulliainen, X. Qiao, Y. Wang, Y. Wen, Y. Wu, G. Yang, L. Yao, R. Yin, G. Zhang, S. Zhang, F. Zheng, Y. Zhou, A. Arola, J. Tamminen, P. Paasonen, Y. Sun, L. Wang, N. M. Donahue, F. Bianchi, K. R. Daellenbach, D. R. Worsnop, V.-M. Kerminen, T. Petäjä, A. Ding, J. Jiang, M. Kulmala
Publikováno v:
Atmospheric Chemistry and Physics, Vol 22, Pp 12207-12220 (2022)
During the COVID-19 lockdown, the dramatic reduction of anthropogenic emissions provided a unique opportunity to investigate the effects of reduced anthropogenic activity and primary emissions on atmospheric chemical processes and the consequent form
Externí odkaz:
https://doaj.org/article/e2efd964ae7d498395e5364e024f0b54
Autor:
Yoshihisa Kobayashi, Geoffrey R. Oxnard, Elizabeth F. Cohen, Navin R. Mahadevan, Joao V. Alessi, Yin P. Hung, Arrien A. Bertram, David E. Heppner, Mauricio F. Ribeiro, Karina P. Sacardo, Rodrigo Saddi, Mariana P. Macedo, Rafael B. Blasco, Jiaqi Li, Kari J. Kurppa, Tom Nguyen, Emma Voligny, Guruprasad Ananda, Roberto Chiarle, Artur Katz, Michael Y. Tolstorukov, Lynette M. Sholl, Pasi A. Jänne
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Fusion genes have been proposed as a potential mechanism of resistance to EGFR tyrosine kinase inhibitors (TKIs) in lung cancer. Here, the authors identify gene fusions that are associated with resistance to EGFR TKIs in non-small cell lung cancers,
Externí odkaz:
https://doaj.org/article/0ceddd06c4bb4ffa905cd1128f416204
Autor:
B. Foreback, L. Dada, K. R. Daellenbach, C. Yan, L. Wang, B. Chu, Y. Zhou, T. V. Kokkonen, M. Kurppa, R. E. Pileci, Y. Wang, T. Chan, J. Kangasluoma, L. Zhuohui, Y. Guo, C. Li, R. Baalbaki, J. Kujansuu, X. Fan, Z. Feng, P. Rantala, S. Gani, F. Bianchi, V.-M. Kerminen, T. Petäjä, M. Kulmala, Y. Liu, P. Paasonen
Publikováno v:
Atmospheric Chemistry and Physics, Vol 22, Pp 11089-11104 (2022)
This study investigates the influence of the Chinese New Year (CNY) celebrations on local air quality in Beijing from 2013 through 2019. CNY celebrations include burning of fireworks and firecrackers, which consequently has a significant short-term i
Externí odkaz:
https://doaj.org/article/6ac6e1bfefe44ff1b20d05cfb8c33c8b
Akademický článek
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