HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth

Autor: Kurosh Ameri, Arman Jahangiri, Anthony M. Rajah, Kathryn V. Tormos, Ravi Nagarajan, Melike Pekmezci, Vien Nguyen, Matthew L. Wheeler, Michael P. Murphy, Timothy A. Sanders, Stefanie S. Jeffrey, Yerem Yeghiazarians, Paolo F. Rinaudo, Joseph F. Costello, Manish K. Aghi, Emin Maltepe

Publikováno v: Cell Reports, Vol 10, Iss 6, Pp 891-899 (2015)

Hypoxia-inducible gene domain family member 1A (HIGD1A) is a survival factor induced by hypoxia-inducible factor 1 (HIF-1). HIF-1 regulates many responses to oxygen deprivation, but viable cells within hypoxic perinecrotic solid tumor regions frequen

Externí odkaz: https://doaj.org/article/073f933d7346420aa940bda4e626e3d6

Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress.

Autor: Kurosh Ameri, Anthony M Rajah, Vien Nguyen, Timothy A Sanders, Arman Jahangiri, Michael Delay, Matthew Donne, Hwa J Choi, Kathryn V Tormos, Yerem Yeghiazarians, Stefanie S Jeffrey, Paolo F Rinaudo, David H Rowitch, Manish Aghi, Emin Maltepe

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e62758 (2013)

Cellular stress responses are frequently governed by the subcellular localization of critical effector proteins. Apoptosis-inducing Factor (AIF) or Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH), for example, can translocate from mitochondria to th

Externí odkaz: https://doaj.org/article/ee0a4dac18304b76af59386115339541

Administration of Interleukin-15 Peptide Improves Cardiac Function in a Mouse Model of Myocardial Infarction

Autor: Raffi Samurkashian, Maxwell Fredkin, Yerem Yeghiazarians, Kurosh Ameri, Dulguun Bayardorj, Vien Nguyen, Eric Fuh

Publikováno v: Journal of cardiovascular pharmacology, vol 75, iss 1
Journal of Cardiovascular Pharmacology

Interleukin-15 is a pleotropic factor, capable of modulating metabolism, survival, proliferation, and differentiation in many different cell types. The rationale behind this study relates to previous work demonstrating that IL-15 is a major factor pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc51fdef370bee6f54a3718727b2e04
https://doi.org/10.1097/fjc.0000000000000764

Tgf-β1/cd105 signaling controls vascular network formation within growth factor sequestering hyaluronic acid hydrogels

Autor: Sivan G. Marcus, Kevin E. Healy, Amit K. Jha, Yerem Yeghiazarians, Shane Browne, Kurosh Ameri

Publikováno v: Browne, Shane; Jha, Amit K; Ameri, Kurosh; Marcus, Sivan G; Yeghiazarians, Yerem; & Healy, Kevin E. (2018). TGF-β1/CD105 signaling controls vascular network formation within growth factor sequestering hyaluronic acid hydrogels. PLOS ONE, 13(3), e0194679. doi: 10.1371/journal.pone.0194679. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/1v02m28f
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194679 (2018)

Cell-based strategies for the treatment of ischemic diseases are at the forefront of tissue engineering and regenerative medicine. Cell therapies purportedly can play a key role in the neovascularization of ischemic tissue; however, low survival and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c9cce1d7a988f5ce02381e2dd591a6
http://hdl.handle.net/10379/10564

Anoxia

Autor: Yerem Yeghiazarians, Adrian L Harris, Kurosh Ameri

Publikováno v: Encyclopedia of Cancer ISBN: 9783642278419

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20fbc85d3bcb261c5d5dba6cceb76738
https://doi.org/10.1007/978-3-642-27841-9_292-2