A toolkit for a modern gynecologic oncology tissue bank.

Autor: Graham O; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Rodriguez J; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Abbott R; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Lomonosova E; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Fashemi B; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Drexler R; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Grither W; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Rodriguez K; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Compadre A; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Loeb M; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Sanders B; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Kuroki L; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Hagemann AR; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., McCourt C; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Thaker PH; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Fuh K; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California San Francisco, CA, United States of America., Powell MA; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Hagemann IS; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States of America., Mutch DG; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Khabele D; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America., Mullen MM; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, and Alvin J. Siteman Cancer Center, St. Louis, MO, United States of America. Electronic address: marymullen@wustl.edu.

Publikováno v: Gynecologic oncology [Gynecol Oncol] 2024 Oct; Vol. 189, pp. 1-8. Date of Electronic Publication: 2024 Jul 05.

RAD51 Foci as a Biomarker Predictive of Platinum Chemotherapy Response in Ovarian Cancer

Autor: Amanda J. Compadre, Lillian N. van Biljon, Mark C. Valentine, Alba Llop-Guevara, Emily Graham, Bisiayo Fashemi, Andrea Herencia-Ropero, Emilee N. Kotnik, Isaac Cooper, Shariska P. Harrington, Lindsay M. Kuroki L, Carolyn K. McCourt, Andrea R. Hagemann, Premal H. Thaker, David G. Mutch, Matthew A. Powell, Lulu Sun, Nima Mosammaparast, Violeta Serra, Peinan Zhao, Elena Lomonosova, Dineo Khabele, Mary M. Mullen

Publikováno v: Clinical Cancer Research. :OF1-OF14

Purpose: To determine the ability of RAD51 foci to predict platinum chemotherapy response in high-grade serous ovarian cancer (HGSOC) patient-derived samples. Experimental Design: RAD51 and γH2AX nuclear foci were evaluated by immunofluorescence in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9bc518f2478ef3623a5d6c775725491
https://doi.org/10.1158/1078-0432.ccr-22-3335

Supplementary Figure S3 from RAD51 Foci as a Biomarker Predictive of Platinum Chemotherapy Response in Ovarian Cancer

Autor: Mary M. Mullen, Dineo Khabele, Elena Lomonosova, Peinan Zhao, Violeta Serra, Nima Mosammaparast, Lulu Sun, Matthew A. Powell, David G. Mutch, Premal H. Thaker, Andrea R. Hagemann, Carolyn K. McCourt, Lindsay M. Kuroki L, Shariska P. Harrington, Isaac Cooper, Emilee N. Kotnik, Andrea Herencia-Ropero, Bisiayo Fashemi, Emily Graham, Alba Llop-Guevara, Mark C. Valentine, Lillian N. van Biljon, Amanda J. Compadre

RAD51 expression and platinum chemotherapy response in vitro and in patient tumors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6034c3b5e3f3ed56a5a8fb8074bcdbc0
https://doi.org/10.1158/1078-0432.22841360

Supplementary Table 4 from RAD51 Foci as a Biomarker Predictive of Platinum Chemotherapy Response in Ovarian Cancer

Autor: Mary M. Mullen, Dineo Khabele, Elena Lomonosova, Peinan Zhao, Violeta Serra, Nima Mosammaparast, Lulu Sun, Matthew A. Powell, David G. Mutch, Premal H. Thaker, Andrea R. Hagemann, Carolyn K. McCourt, Lindsay M. Kuroki L, Shariska P. Harrington, Isaac Cooper, Emilee N. Kotnik, Andrea Herencia-Ropero, Bisiayo Fashemi, Emily Graham, Alba Llop-Guevara, Mark C. Valentine, Lillian N. van Biljon, Amanda J. Compadre

Patient characteristics of FFPE discovery cohort

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fc165dba95eab1776bc1b6b51ad303
https://doi.org/10.1158/1078-0432.22841339.v1

Data from RAD51 Foci as a Biomarker Predictive of Platinum Chemotherapy Response in Ovarian Cancer

Autor: Mary M. Mullen, Dineo Khabele, Elena Lomonosova, Peinan Zhao, Violeta Serra, Nima Mosammaparast, Lulu Sun, Matthew A. Powell, David G. Mutch, Premal H. Thaker, Andrea R. Hagemann, Carolyn K. McCourt, Lindsay M. Kuroki L, Shariska P. Harrington, Isaac Cooper, Emilee N. Kotnik, Andrea Herencia-Ropero, Bisiayo Fashemi, Emily Graham, Alba Llop-Guevara, Mark C. Valentine, Lillian N. van Biljon, Amanda J. Compadre

Purpose:To determine the ability of RAD51 foci to predict platinum chemotherapy response in high-grade serous ovarian cancer (HGSOC) patient-derived samples.Experimental Design:RAD51 and γH2AX nuclear foci were evaluated by immunofluorescence in HGS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a93711202a80d4796c48648f0a5eaf3
https://doi.org/10.1158/1078-0432.c.6649139.v1