Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma.

Autor: Usta SZ; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita 565-0871, Osaka, Japan., Uchihashi T; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita 565-0871, Osaka, Japan., Kodama S; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita 565-0871, Osaka, Japan., Kurioka K; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita 565-0871, Osaka, Japan., Inubushi T; Department of Orthodontics & Dentofacial Orthopedics, Graduate School of Dentistry, Osaka University, Suita 565-0871, Osaka, Japan., Shimooka T; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita 565-0871, Osaka, Japan., Sugauchi A; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita 565-0871, Osaka, Japan.; Unit of Dentistry, Osaka University Hospital, 2-15, Yamadaoka, Suita 565-0871, Osaka, Japan., Seki S; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita 565-0871, Osaka, Japan., Tanaka S; Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita 565-0871, Osaka, Japan.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 08; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 08.

TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-3.

Autor: Takahashi K; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo 113-8549, Japan., Podyma-Inoue KA; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo 113-8549, Japan., Saito M; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo 113-8549, Japan., Sakakitani S; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo 113-8549, Japan; Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo 113-8549, Japan., Sugauchi A; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565-0871, Japan., Iida K; Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan., Iwabuchi S; Department of Molecular Pathophysiology, Wakayama Medical University, Wakayama 641-8509, Japan., Koinuma D; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan., Kurioka K; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565-0871, Japan., Konishi T; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan., Tanaka S; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565-0871, Japan., Kaida A; Department of Oral Radiation Oncology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo 113-8549, Japan., Miura M; Department of Oral Radiation Oncology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo 113-8549, Japan., Hashimoto S; Department of Molecular Pathophysiology, Wakayama Medical University, Wakayama 641-8509, Japan., Okada M; Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan., Uchihashi T; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565-0871, Japan; Unit of Dentistry, Osaka University Hospital, Suita, Osaka 565-0871, Japan., Miyazono K; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan., Watabe T; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo 113-8549, Japan. Electronic address: t-watabe.bch@tmd.ac.jp.

Publikováno v: Cell reports [Cell Rep] 2022 Sep 27; Vol. 40 (13), pp. 111411.

Progression of melanoma is suppressed by targeting all transforming growth factor‑β isoforms with an Fc chimeric receptor.

Autor: Kodama S; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565‑0871, Japan., Podyma-Inoue KΑ; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo, Tokyo 113‑8549, Japan., Uchihashi T; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565‑0871, Japan., Kurioka K; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565‑0871, Japan., Takahashi H; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo, Tokyo 113‑8549, Japan., Sugauchi A; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565‑0871, Japan., Takahashi K; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo, Tokyo 113‑8549, Japan., Inubushi T; Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Osaka University, Suita, Osaka 565‑0871, Japan., Kogo M; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565‑0871, Japan., Tanaka S; The First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita, Osaka 565‑0871, Japan., Watabe T; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Bunkyo, Tokyo 113‑8549, Japan.

Publikováno v: Oncology reports [Oncol Rep] 2021 Sep; Vol. 46 (3). Date of Electronic Publication: 2021 Jul 23.

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Isolation of cancer cells with augmented spheroid-forming capability using a novel tool equipped with removable filter.

Autor: Fujibayashi E; First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita 565-0871, Osaka, Japan., Yabuta N; Department of Molecular Genetics, Research Institute for Microbial Diseases, Osaka University, Suita 565-0871, Osaka, Japan., Nishikawa Y; Department of Molecular Genetics, Research Institute for Microbial Diseases, Osaka University, Suita 565-0871, Osaka, Japan., Uchihashi T; First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita 565-0871, Osaka, Japan., Miura D; Department of Pharmacy, Hyogo University of Health Sciences, Kobe 650-8530, Japan., Kurioka K; First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita 565-0871, Osaka, Japan., Tanaka S; First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita 565-0871, Osaka, Japan., Kogo M; First Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University, Suita 565-0871, Osaka, Japan., Nojima H; Department of Molecular Genetics, Research Institute for Microbial Diseases, Osaka University, Suita 565-0871, Osaka, Japan.

Publikováno v: Oncotarget [Oncotarget] 2018 Sep 21; Vol. 9 (74), pp. 33931-33946. Date of Electronic Publication: 2018 Sep 21 (Print Publication: 2018).